Abstract: The present disclosure relates to a series of tricyclic compounds, their tautomers, polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of treating conditions and diseases that are mediated by adenosine receptor (AR) activity. The disclosure also relates to process of preparation of these tricyclic compounds of Formula I. These compounds are useful in the treatment, prevention or suppression of diseases and disorders that may be susceptible to improvement by antagonism of the adenosine receptor. The disclosure also relates to the process of preparation of the tricyclic compounds, and to pharmaceutical compositions containing them.

Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: Embodiments are for generating a digital signature of a query execution plan using similarity hashing. A technique includes generating a node digital signature for nodes in a query and generating an edge digital signature for edges in the query, the edges connecting the nodes. The technique includes selecting at least one previously executed query based on the node digital signature and the edge digital signature for the query and causing the query to be processed according to an assignment associated with the at least one previously executed query.

Abstract: An infant care apparatus cooler facilitates the cooling of components with elevated temperatures such as a convective heater in an infant care apparatus. The infant care apparatus includes an energy storage device and a fan. In the presence of an external source of power, the fan operates to circulate air to be heated by the heating coil and in the absence of external power, the fan is operable with energization from the energy storage device to circulate air past the heating coil, cooling the heating coil.

Abstract: A method and video capture device is provided having a front camera for capturing images of a front scene initially having an object of interest for the user of the device. A rear camera is also included and configured to capture images of the head of a user of the device. The rear camera also includes a processing circuit to estimate the eye movement of the user and the displacement of the object of interest in the front scene captured from the estimated eye movement of the user. The rear camera further includes a decision making circuit to determine, from the estimated displacement of the object of interest, if the object of interest leaves the captured front scene and, when that is the case triggers an action.

Abstract: An infant care apparatus cooler facilitates the cooling of components with elevated temperatures such as a convective heater in an infant care apparatus. The infant care apparatus includes an energy storage device and a fan. In the presence of an external source of power, the fan operates to circulate air to be heated by the heating coil and in the absence of external power, the fan is operable with energization from the energy storage device to circulate air past the heating coil, cooling the heating coil.

Abstract: A technique for improving the performance of image classification systems is proposed which consists of learning an adaptation architecture on top of the input features jointly with linear classifiers, e.g., SVM. This adaptation method is agnostic to the type of input feature and applies either to features built using aggregators, e.g., BoW, FV, or to features obtained from the activations or outputs from DCNN layers. The adaptation architecture may be single (shallow) or multi-layered (deep). This technique achieves a higher performance compared to current state of the art classification systems.

Abstract: A method for processing in an encoder, the method comprising receiving, by the encoder, a set of local descriptors derived from an image, obtaining, by the encoder, K code words, wherein K>1; and determining, by the encoder, a first element of a bag-of-words image feature vector by using a differentiable function having a difference between each of the local descriptors and one of the K code words as a first parameter, wherein each of the K code words is used in the differentiable function for determining a different element of the bag-of-words image feature vector.

Abstract: The present invention discloses a software solution for localization/globalization of software applications. Localization refers to a language specific version of globalized software. The invention can generate externalized language specific files that are decoupled from source code, while alleviating many mistakes and problems inherent in legacy localization methodologies. That is, the invention provides an end-to-end framework that automatically replaces source code strings with placeholders, which are linked to national language (NL) specific strings of a target language. During build time, an executable can be generated that is customized for the target language. The original source code remains unchanged, which makes the globalization process described transparent to software developers. Further, the placeholders are automatically generated for each build, which resolves many problems with manually specifying keys that replace text, such as orphaned keys, duplicate keys, and the like.

Abstract: The present invention includes compositions and methods for the treatment of animals that are immunosuppressed by preparing a topical composition supplemented with one or more compounds selected from the group consisting of nucleotides, nucleosides, nucleobases and mixtures thereof in an amount effective for promoting wound healing and contacting the wound of the immunosuppressed mammal with the topical composition.

Abstract: Thermal, acoustic, and/or power data is collected about a platform, in its runtime environment. A component of the platform is selected, and predetermined data traffic is forced through the component while collecting the data. Characterization data for the platform is derived, from the collected data, and stored for access by a driver for the platform. Other embodiments are also described and claimed.