Patents by Inventor Anil Kumar Gupta
Anil Kumar Gupta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11708348Abstract: Provided herein are compounds of Formula (I), their pharmaceutically acceptable salts, and their pharmaceutical compositions: wherein R1, R2, R3a, R3b, R4, R5, and A are defined in the present disclosure. The compounds are potent inhibitors of the main protease (Mpro) of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), and they are useful in treating or preventing COVID-19 in a subject.Type: GrantFiled: June 10, 2022Date of Patent: July 25, 2023Assignee: The Scripps Research InstituteInventors: Arnab K. Chatterjee, Jian Jeffrey Chen, Elshan Nakath, Alireza Rahimi, Anil Kumar Gupta, Gennadii Grabovyi, Katy Wilson, Sourav Ghorai, Armen Nazarian, James Pedroarena, Wrickban Mazumdar, Frank Weiss, Lirui Song, Malina A. Bakowski, Laura Riva, Karen Wolff, Case W. McNamara, Thomas F. Rogers, Jacqueline Malvin, Shuangwei Li, Sean Joseph, Ashley Woods, Yuyin Liu, Neechi Okwor
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Publication number: 20230111793Abstract: Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria.Type: ApplicationFiled: October 27, 2022Publication date: April 13, 2023Inventors: WIL JOSEPH ANDAHAZY, ARNAB K. CHATTERJEE, CASE W. MCNAMARA, FEDERICO C. BEASLEY, ANDERS MIKAL ELIASEN, HANK MICHAEL JAMES PETRASSI, JASON T. ROLAND, TIMOTHY WELLS, OLGA VLADIMIROVNA ZATOLOCHNAYA, FEI ZHOU, PETER G. SCHULTZ, ANIL KUMAR GUPTA
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Publication number: 20230033285Abstract: Provided herein are compounds of Formula (I), their pharmaceutically acceptable salts, and their pharmaceutical compositions: wherein R1, R2, R3a, R3b, R4, R5, and A are defined in the present disclosure. The compounds are potent inhibitors of the main protease (Mpro) of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), and they are useful in treating or preventing COVID-19 in a subject.Type: ApplicationFiled: June 16, 2022Publication date: February 2, 2023Inventors: Arnab K. Chatterjee, Jian Jeffrey Chen, Elshan Nakath, Alireza Rahimi, Anil Kumar Gupta, Gennadii Grabovyi, Katy Wilson, Sourav Ghorai, Armen Nazarian, James Pedroarena, Wrickban Mazumdar, Frank Weiss, Lirui Song, Malina A. Bakowski, Laura Riva, Karen Wolff, Case W. McNamara, Thomas F. Rogers, Jacqueline Malvin, Shuangwei Li, Sean Joseph, Ashley Woods, Yuyin Liu, Neechi Okwor
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Publication number: 20230024012Abstract: Provided herein are compounds of Formula (I), their pharmaceutically acceptable salts, and their pharmaceutical compositions: wherein R1, R2, R3a, R3b, R4, R5, and A are defined in the present disclosure. The compounds are potent inhibitors of the main protease (Mpro) of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), and they are useful in treating or preventing COVID-19 in a subject.Type: ApplicationFiled: June 10, 2022Publication date: January 26, 2023Inventors: Arnab K. Chatterjee, Jian Jeffrey Chen, Elshan Nakath, Alireza Rahimi, Anil Kumar Gupta, Gennadii Grabovyi, Katy Wilson, Sourav Ghorai, Armen Nazarian, James Pedroarena, Wrickban Mazumdar, Frank Weiss, Lirui Song, Malina A. Bakowski, Laura Riva, Karen Wolff, Case W. McNamara, Thomas F. Rogers, Jacqueline Malvin, Shuangwei Li, Sean Joseph, Ashley Woods, Yuyin Liu, Neechi Okwor
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Patent number: 11485697Abstract: Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria.Type: GrantFiled: February 17, 2021Date of Patent: November 1, 2022Assignee: THE SCRIPPS RESEARCH INSTITUTEInventors: Wil Joseph Andahazy, Arnab K. Chatterjee, Case W. Mcnamara, Federico C. Beasley, Anders Mikal Eliasen, Hank Michael James Petrassi, Jason T. Roland, Timothy Wells, Olga Vladimirovna Zatolochnaya, Fei Zhou, Peter G. Schultz, Anil Kumar Gupta
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Publication number: 20210179524Abstract: Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria.Type: ApplicationFiled: February 17, 2021Publication date: June 17, 2021Inventors: WIL JOSEPH ANDAHAZY, ARNAB K. CHATTERJEE, CASE W. MCNAMARA, FEDERICO C. BEASLEY, ANDERS MIKAL ELIASEN, HANK MICHAEL JAMES PETRASSI, JASON T. ROLAND, TIMOTHY WELLS, OLGA VLADIMIROVNA ZATOLOCHNAYA, FEI ZHOU, PETER G. SCHULTZ, ANIL KUMAR GUPTA
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Patent number: 10947176Abstract: Provided herein are compounds, compositions and method of using thereof to treat or prevent malaria.Type: GrantFiled: June 19, 2017Date of Patent: March 16, 2021Assignee: THE SCRIPPS RESEARCH INSTITUTEInventors: Wil Joseph Andahazy, Arnab K. Chatterjee, Case W. McNamara, Federico C. Beasley, Anders Mikal Eliasen, Hank Michael James Petrassi, Jason T. Roland, Timothy Wells, Olga Vladimirovna Zatolochnaya, Fei Zhou, Peter G. Schultz, Anil Kumar Gupta
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Patent number: 9909100Abstract: This invention relates to a culture medium for cultivation of Leishmania promastigotes, comprising inorganic salts, organic constituents and peptone/hydrolystate and at least one plant extract.Type: GrantFiled: April 25, 2014Date of Patent: March 6, 2018Assignee: Indian Council of Medical ResearchInventors: Pradeep Das, Anil Kumar Gupta
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Publication number: 20170004543Abstract: A social networking system receives an advertisement from a user for posting on the system. The system verifies that the advertisement meets a first set of criteria, and in response to verifying that the advertisement meets the first set of criteria, the system receives a submission of the advertisement from the user for further processing. The system then verifies that the advertisement meets a second set of criteria, and in response to verifying that the advertisement meets the second set of criteria, the system immediately approves the advertisement for display on the system.Type: ApplicationFiled: June 30, 2015Publication date: January 5, 2017Inventors: Venkata S.J.R. Bhamidipati, Anil Kumar Gupta, Zhifeng Deng
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Publication number: 20160010053Abstract: This invention relates to a culture medium for cultivation of Leishmania promastigotes, comprising inorganic salts, organic constituents and peptone/hydrolystate and at least one plant extract.Type: ApplicationFiled: April 25, 2014Publication date: January 14, 2016Applicant: Indian Council of Medical ResearchInventors: Pradeep Das, Anil Kumar Gupta
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Publication number: 20150254589Abstract: System(s) and method(s) to provide inventory optimization in a multi-echelon supply chain network are disclosed. An input data comprising one or more product supply parameters along with an uncertainty factor associated with the product supply parameters are received through a configurable user interface. The input data is used to create a multi-echelon supply chain network. Supplier nodes are selected based on optimizing parameters and are allocated with respect to demand nodes. A lead time demand and a safety stock parameter are calculated. An optimal inventory plan is generated for each supply chain member associated with the supply chain network along with the safety stock parameter by minimizing the uncertainty factor thereby providing the inventory optimization. The optimal inventory plan is displayed in one or more parameters over the configurable user interface.Type: ApplicationFiled: June 23, 2014Publication date: September 10, 2015Inventors: Avneet Saxena, Anil Kumar Gupta
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Patent number: 9018226Abstract: The present invention relates to bioactive extracts its fractions and isolation of compound from Rauwolfia tetraphylla. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D2, Cholinergic (muscarinic) and Serotonergic (5HT2A) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-demethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and ?-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkaloids of formula 1 and 2 from the leaves of Rauwolfia tetraphylla. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions of R.Type: GrantFiled: March 31, 2010Date of Patent: April 28, 2015Assignee: Council of Scientific & Industrial ResearchInventors: Santosh Kumar Srivastava, Ashok Kumar Agrawal, Subhash Chandra Singh, Vinay Kumar Khanna, Janardan Singh, Chandeshwar Nath, Madan Mohan Gupta, Shikha Gupta, Ram Kishor Verma, Anirban Pal, Dnyaneshwar Umrao Bawankule, Dharmendra Saikia, Anil Kumar Gupta, Anupam Maurya, Suman Preet Singh Khanuja
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Patent number: 8620885Abstract: Many public utilities companies employ meter data management systems (MDMSs) to manage the millions and sometimes billions of daily and interval meter read values that they collect during a single billing period. One problem with some MDMSs estimate missing daily reads based on average daily usage and these estimates do not match daily usage values determined from interval read data, causing sum check exceptions. Such exceptions are undesirable because they can lead to billing errors and lost consumer confidence in the utility, among other things. To address this, the present inventors devised an exemplary system that uses good and estimated interval read data to more accurately estimate the missing daily reads and thereby reduce occurrences of sum check exceptions. The exemplary system also estimates missing time of use and demand data based on interval read data.Type: GrantFiled: February 16, 2010Date of Patent: December 31, 2013Assignee: Ecologic Analytics, LLCInventors: Anil Kumar Gupta, David James Hubbard, Jerome Frank Winzig
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Publication number: 20130203711Abstract: The invention relates to a herbal oil, for controlling blood sugar without risk of hypoglycemia, comprising of the step of (i) fractional distillation of essential oils comprising of turpentine oil, jasmine oil, rose oil, eucalyptus oil, sandal wood oil and water green oil to obtain hydroxyl compounds #-terpinol, linalool, Gereneol, Citroneoll, #-Santalol, Methyl salicylate and other alcoholic terpenoils and (ii) dilution with fat oil so as to have approximate weight percentage of #-terpinol 50%, linalool 6%, Gereneol 4%, Citroneoll 3.5%, #-Santalol 2.7%, Methyl salicylate 2%, other alcoholic terpenoils and fat oil 31.8%.Type: ApplicationFiled: October 4, 2011Publication date: August 8, 2013Inventor: Anil Kumar Gupta
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Publication number: 20120184576Abstract: The present invention relates to bioactive extracts its fractions and isolation of compound from Rauwolfia tetraphylla. The extracts and fractions are useful for the treatment of psychosis based on in-vivo validation on animal model and proportional binding affinities for dopaminergic-D2, Cholinergic (muscarinic) and Serotonergic (5HT2A) receptors for antipsychotic activity. The present invention relates to novel antipsychotic activity in the leaf alkaloids of Formula 1 and 2 named tetrahydroalstonine, 10-methoxytetrahydroalstonine, isoreserpiline, 10-der?ethoxyreserpiline, 11-demethoxyreserpiline, reserpiline and ?-yohimbine. The present invention also relates to processes for obtaining antipsychotic extracts as well as for the isolation of alkabids of formula 1 and 2 from the leaves of Rauwolfia tetraphylla. The present invention particularly relates to significant antipsychotic activity in the MeOH extract, ethylacetate and chloroform fractions of R.Type: ApplicationFiled: March 31, 2010Publication date: July 19, 2012Inventors: Santosh Kumar Srivastava, Ashok Kumar Agrawal, Subhash Chandra Singh, Vinay Kumar Khanna, Janardan Singh, Chandeshwar Nath, Madan Mohan Gupta, Shikha Gupta, Ram Kishor Verma, Anirban Pal, Duyaneshwar Umrao Bawankule, Dharmendra Saikia, Anil Kumar Gupta, Anupam Maurya, Suman Preet Singh Khanuja
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Patent number: 7955663Abstract: Processes for the simultaneous and selective growth of single walled and multiwalled carbon nanotubes in a single set of experiments are disclosed. The processes may include preparing a graphite electrode rod containing catalyst selected from Fe, Co, Ni, and a mixture thereof, acting as an anode. The process may include preparing another graphite electrode rod, each electrode having a distal and a proximal end. The process may include placing the above said two electrodes parallel to each other and their axis being substantially aligned in a chamber. The process may further include creating a DC-arc discharge inside the chamber by applying a DC-current voltage. The process may further include an cooling assembly having a cooling coil that surrounds the two electrodes. The cooling assembly may be used to maintain a temperature gradient that permits the depositing of single walled and multiwalled carbon nanotubes simultaneously in one experiment.Type: GrantFiled: November 5, 2007Date of Patent: June 7, 2011Assignee: Council of Scientific and Industrial ResearchInventors: Rakesh Behari Mathur, Chhotey Lal Nil, Tersem Lal Dhami, Bhanu Pratap Singh, Anil Kumar Gupta, Jagdish Ghawana
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Publication number: 20110092585Abstract: The present invention provides a novel pharmaceutical composition consisting of a combination of three coumarinolignoids of formula 1, 2 and 3 isolated from the seeds of the plant Cleome viscosa along with a pharmaceutically acceptable carrier useful as a immunomodulator. The invention also describes the ability of the compounds to modulate humorral and cell mediated immune response. It further provides a process for the preparation of a novel pharmaceutical composition of the said three coumarinolignoids in an optimized ratio to modulate humorral and cell mediated immune response.Type: ApplicationFiled: September 1, 2010Publication date: April 21, 2011Applicants: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Suman Preet Singh Khanuja, Anirban Pal, Sunil Kumar Chattopadhyay, Mahendra Pandurang Darokar, Rajendra Prasad Patel, Anil Kumar Gupta, Arvind Singh Negi, Tanpreet Kaur, Sudeep Tandon, Atul Prakash Kahol, Ankur Garg
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Patent number: 7527814Abstract: The invention provides a simple method for isolation of calliterpenone (16?,17 dihydroxy-3-oxo phyllocladane), a phyllocladane diterpenoid with the plant growth regulating properties, from plant genus Callicarpa.Type: GrantFiled: January 30, 2007Date of Patent: May 5, 2009Assignee: Council of Scientific and Industrial ResearchInventors: Anil Kumar Singh, Suman Preet Singh Khanuja, Sudeep Tandon, Alok Kalra, Deeptanjali Sahoo, Atul Prakash Kahol, Madan Mohan Gupta, Ram Kishor Verma, Arun Kumar Kukreja, Mansoor Alam, Guru Das Bagachi, Ravi Prakash Bansal, Mahendra Pandurang Darokar, Anil Kumar Gupta
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Patent number: 7446243Abstract: The present invention relates to a cultivar of Phyllanthus amarus ‘CIM-Jeevan’, producing high amount of herb, phyllanthin and hypophyllanthin, wherein said cultivar is developed through ?-irradiation of superior germplasm, the said plant produces high amount of herbage yield ranging between 1.0-1.15 kg per sqm fresh total plant herb, possesses high vegetative erect growth with a height ranging between 60 to 65 cm, produces phyllanthin ranging between 0.70-0.77% in dry herb, produces hypophyllanthin ranging between 0.32-0.37% in dry herb, and shows seed germination of about 90%.Type: GrantFiled: August 25, 2003Date of Patent: November 4, 2008Assignee: Council of Scientific and Industrial ResearchInventors: Anil Kumar Gupta, Suman Preet Singh Khanuja, Madan Mohan Gupta, Ajit Kumar Shasany, Neeraj Jain, Ram Kishor Verma, Mahendra Pandurang Darokar, Guru Das Bagchi, Sushil Kumar
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Patent number: 7435877Abstract: Indian basil, Ocimum basilicum, belongs to the family of Lamiaceae. The essential oil of Indian basil extracted via hydro or steam distillation from the leaves or whole plants is used to flavor foods, dental and oral products, in fragrances, and in traditional rituals and medicines. Extracted essential oil has also been shown to contain biologically active constituents that are insecticidal, nematicidal, fungistatic or which have antimicrobial properties. The present invention relates to the development of an early, short duration, dwarf, high essential oil, methy chavicol and linalool yielding variety of Indian basil (Ocimum basilicum). Family—Lamiaceae) named as ‘CIM-SAUMYA’. This new variety of Indian basil was developed through open pollination in the germplasm followed by half-sib progeny selection and evaluation for the yield characters of selected population for 3 years in field conditions.Type: GrantFiled: August 6, 2004Date of Patent: October 14, 2008Assignee: Council of Scientific & Industrial ResearchInventors: Suman Preet Singh Khanuja, Raj Kishori Lal, Arun Kumar Agnihotri, Ajit Kumar Shasany, Ali Arif Naqvi, Samresh Dwivedi, Hari Om Misra, Om Prakesh Dhawan, Alok Kalra, Aparbal Singh, Janak Raj Bahl, Saudan Singh, Dharani Dhar Patra, Shilpi Agarwal, Mahendra Pandurang Darokar, Anil Kumar Gupta, Moti Lal Gupta, Ram Chandra