Abstract: The current invention discloses an easy to use two-in-one cleaning towel. The cleaning towel may have a single layer of flexible and absorbent sheet having a first side and a second side, wherein a cleaning agent is attached to the second side. Alternatively, the cleaning towel may have multiple layers of overlapping sheet materials, with a first layer made from flexible and absorbent material and a second layer having a cleaning agent attached to it. The cleaning agent is preferably in solid form at room temperature, keeping the cleaning towel substantially dry. The preferred material to make the cleaning towel is paper. The two layers or two sides may have different colors. A user may wipe a spill with one side/layer of the cleaning towel, turn it over, and disinfect the target surface with the other side/layer.