Patents by Inventor Anil Oroskar

Anil Oroskar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160186092
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of: (i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and (ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and (iii) purifying the second intermediate product obtained in (ii) in a simulated or actual moving bed chromatographic separation step, to obtain the PUFA product; wherein an aqueous organic solvent is used as eluent in each separation step; saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step; the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and the PUFA product obtained in the t
    Type: Application
    Filed: March 10, 2016
    Publication date: June 30, 2016
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9370730
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, wherein the apparatus has a plurality of zones comprising at least a first zone and second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA prod
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: June 21, 2016
    Assignee: BASF PHARMA CALLANISH LIMITED
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9347020
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises passing the feed mixture through one or more chromatographic columns containing, as eluent, an aqueous organic solvent, wherein the temperature of at least one of the chromatographic columns through which the feed mixture is passed is greater than room temperature.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: May 24, 2016
    Assignee: BASF Pharma Callanish Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9321715
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous alcohol, wherein the apparatus has a plurality of zones comprising at least a first zone and second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA product bein
    Type: Grant
    Filed: December 24, 2010
    Date of Patent: April 26, 2016
    Assignee: BASF Pharma (Callanish) Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9315762
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of: (i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and (ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and (iii) purifying the second intermediate product obtained in (ii) in a simulated or actual moving bed chromatographic separation step, to obtain the PUFA product; wherein an aqueous organic solvent is used as eluent in each separation step; saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step; the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and the PUFA product obtained in the th
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 19, 2016
    Assignee: BASF Pharma Callanish Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9260677
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises the steps of: (i) purifying the feed mixture in a first separation step in a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain an intermediate product; and (ii) purifying the intermediate product obtained in (i) in a second separation step using a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain the PUFA product; wherein (a) the first and second separation steps are carried out sequentially on the same chromatography apparatus, the intermediate product being recovered between the first and second separation steps and the process conditions in the chromatography apparatus being adjusted between the first an
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: February 16, 2016
    Assignee: BASF Pharma Callanish Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20160016877
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous alcohol, wherein the apparatus has a plurality of zones comprising at least a first zone and a second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA product be
    Type: Application
    Filed: September 30, 2015
    Publication date: January 21, 2016
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9234157
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises the steps of: (i) purifying the feed mixture in a first separation step in a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain an intermediate product; and (ii) purifying the intermediate product obtained in (i) in a second separation step using a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain the PUFA product; wherein (a) the first and second separation steps are carried out sequentially on the same chromatography apparatus, the intermediate product being recovered between the first and second separation steps and the process conditions in the chromatography apparatus being adjusted between the first an
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: January 12, 2016
    Assignee: BASF Pharma Callanish Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 9163050
    Abstract: Disclosed is a process for the production of d-mannose from fermented palm oil kernel meal using a continuous SMB separation process. The process is useful for providing a simplified processing route to providing high purity d-mannose. The SMB process and the SMB cycle was operated to provide a high purity mannose stream comprising d-mannose, salts, and color agents, a primary raffinate comprising glucose, other sugars and salts, and a secondary raffinate consisting essentially of the mobile phase desorbent. In the SMB cycle, the secondary raffinate was recycled to the SMB process as the mobile phase desorbent without further desalination. The highly pure mannose stream was further treated to remove color agents and salts prior to subsequent steps of precipitation or crystallization and drying. D-mannose is useful as a food additive, as a sweetener, as a texturizer, as a stabilizer, or as a humectant.
    Type: Grant
    Filed: August 6, 2012
    Date of Patent: October 20, 2015
    Assignee: OROCHEM TECHNOLOGIES, INC.
    Inventors: Anil R Oroskar, Naveen S Sudharsan, Priyanka Anil Oroskar, Omkar M Kulkarni
  • Publication number: 20150166929
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture which is a fish oil or which is derived from fish oil, which process comprises the steps of: (i) purifying the feed mixture in a chromatographic separation step, to obtain a first intermediate product; and (ii) purifying the first intermediate product obtained in (i) in a simulated or actual moving bed chromatographic separation step, to obtain a second intermediate product; and (iii) purifying the second intermediate product obtained in (ii) in a simulated or actual moving bed chromatographic separation step, to obtain the PUFA product; wherein an aqueous organic solvent is used as eluent in each separation step; saturated and/or monounsaturated fatty acids present in the feed mixture are removed in the first separation step; the PUFA product is separated from different components of the feed mixture in steps (ii) and (iii); and the PUFA product obtained in the th
    Type: Application
    Filed: July 6, 2012
    Publication date: June 18, 2015
    Applicant: BASF Pharma (Callanish)Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Patent number: 8937191
    Abstract: Disclosed is a process for the production of high purity alpha-tocotrienol from palm oil extract. More particularly, the invention relates to a process for the separation of alpha-tocotrienol from a mixtures of other tocotrienols and tocopherols and the use of a simplified separation scheme based on a combination of solid phase extraction and simulated moving bed (SMB) separation steps employing polar phase simulated moving bed operation. The process is useful for providing a continuous route and a simplified processing route to providing pure alpha-tocotrienol as a major product essentially free of other tocotrienols and tocopherols including: beta-tocopherol, gamma-tocotrienol, delta-tocotrienol, gamma-tocopherol, delta-tocopherol, front end and back end carotenoids, and alpha-tocopherol as a by-product from palm oil extract. Alpha-tocotrienol is a form of vitamin E and may be useful as a treatment for preventing stroke or reducing brain and nerve damage following a stroke.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: January 20, 2015
    Assignee: OROCHEM Technologies, Inc.
    Inventors: Anil Oroskar, Deepak Sharma, Vanshidhar Singh, Anand Oroskar, Gautham Oroskar
  • Publication number: 20140200360
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises the steps of: (i) purifying the feed mixture in a first separation step in a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain an intermediate product; and (ii) purifying the intermediate product obtained in (i) in a second separation step using a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain the PUFA product; wherein (a) the first and second separation steps are carried out sequentially on the same chromatography apparatus, the intermediate product being recovered between the first and second separation steps and the process conditions in the chromatography apparatus being adjusted between the first an
    Type: Application
    Filed: July 6, 2012
    Publication date: July 17, 2014
    Applicant: BASF Pharma (Callanish) Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20140194636
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, wherein the apparatus has a plurality of zones comprising at least a first zone and second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA prod
    Type: Application
    Filed: July 6, 2012
    Publication date: July 10, 2014
    Applicant: BASF Pharma (Callanish) Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20140179933
    Abstract: Disclosed is a process for the production of high purity alpha-tocotrienol from palm oil extract. More particularly, the invention relates to a process for the separation of alpha-tocotrienol from a mixtures of other tocotrienols and tocopherols and the use of a simplified separation scheme based on a combination of solid phase extraction and simulated moving bed (SMB) separation steps employing polar phase simulated moving bed operation. The process is useful for providing a continuous route and a simplified processing route to providing pure alpha-tocotrienol as a major product essentially free of other tocotrienols and tocopherols including: beta-tocopherol, gamma-tocotrienol, delta-tocotrienol, gamma-tocopherol, delta-tocopherol, front end and back end carotenoids, and alpha-tocopherol as a by-product from palm oil extract. Alpha-tocotrienol is a form of vitamin E and may be useful as a treatment for preventing stroke or reducing brain and nerve damage following a stroke.
    Type: Application
    Filed: December 20, 2012
    Publication date: June 26, 2014
    Applicant: OROCHEM TECHNOLOGIES, INC.
    Inventors: Anil Oroskar, Deepak Sharma, Vanshidhar Singh, Anand Oroskar, Gautham Oroskar
  • Publication number: 20140128627
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises the steps of: (i) purifying the feed mixture in a first separation step in a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain an intermediate product; and (ii) purifying the intermediate product obtained in (i) in a second separation step using a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous organic solvent, to obtain the PUFA product; wherein (a) the first and second separation steps are carried out sequentially on the same chromatography apparatus, the intermediate product being recovered between the first and second separation steps and the process conditions in the chromatography apparatus being adjusted between the first an
    Type: Application
    Filed: July 6, 2012
    Publication date: May 8, 2014
    Applicant: BASF Pharma (Callanish ) Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20140107359
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product from a feed mixture, which process comprises passing the feed mixture through one or more chromatographic columns containing, as eluent, an aqueous organic solvent, wherein the temperature of at least one of the chromatographic columns through which the feed mixture is passed is greater than room temperature.
    Type: Application
    Filed: July 6, 2012
    Publication date: April 17, 2014
    Applicant: BASF Pharma(Callanish)Limited
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20140039180
    Abstract: Disclosed is a process for the production of d-mannose from fermented palm oil kernel meal using a continuous SMB separation process. The process is useful for providing a simplified processing route to providing high purity d-mannose. The SMB process and the SMB cycle was operated to provide a high purity mannose stream comprising d-mannose, salts, and color agents, a primary raffinate comprising glucose, other sugars and salts, and a secondary raffinate consisting essentially of the mobile phase desorbent. In the SMB cycle, the secondary raffinate was recycled to the SMB process as the mobile phase desorbent without further desalination. The highly pure mannose stream was further treated to remove color agents and salts prior to subsequent steps of precipitation or crystallization and drying. D-mannose is useful as a food additive, as a sweetener, as a texturizer, as a stabilizer, or as a humectant.
    Type: Application
    Filed: August 6, 2012
    Publication date: February 6, 2014
    Applicant: OROCHEM TECHNOLOGIES, INC.
    Inventors: Anil R. Oroskar, Naveen S. Sudharsan, Priyanka Anil Oroskar, Omkar M. Kulkarni
  • Patent number: 8471052
    Abstract: A process is disclosed for producing organic nitriles such as Acetonitrile or Hydrogen Cyanide, in which yields may exceed 90%, undesirable by-products are not produced, and handling of ammonia gas is avoided. In one aspect, a process includes preparing a feed including ammonium salts and water; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst. The catalyst may advantageously include molybdenum on a silica or silica alumina support. The feed may be ammonium acetate in water with about 50 wt % ammonium acetate and the balance water or ammonium formate in water. In another aspect, a process includes preparing a feed including ammonium hydroxide and acetic acid; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: June 25, 2013
    Assignee: Orochem Technologies Inc.
    Inventors: Anil Oroskar, Paul Roman Kurek, Asha Oroskar
  • Publication number: 20120330043
    Abstract: The present invention provides a chromatographic separation process for recovering a polyunsaturated fatty acid (PUFA) product, from a feed mixture, which process comprises introducing the feed mixture to a simulated or actual moving bed chromatography apparatus having a plurality of linked chromatography columns containing, as eluent, an aqueous alcohol, wherein the apparatus has a plurality of zones comprising at least a first zone and second zone, each zone having an extract stream and a raffinate stream from which liquid can be collected from said plurality of linked chromatography columns, and wherein (a) a raffinate stream containing the PUFA product together with more polar components is collected from a column in the first zone and introduced to a nonadjacent column in the second zone, and/or (b) an extract stream containing the PUFA product together with less polar components is collected from a column in the second zone and introduced to a nonadjacent column in the first zone, said PUFA product bein
    Type: Application
    Filed: December 24, 2010
    Publication date: December 27, 2012
    Applicant: BASF PHARMA (CALLANISH) LIMITED
    Inventors: Adam Kelliher, Angus Morrison, Anil Oroskar, Rakesh Vikraman Nair Rema, Abhilesh Agarwal
  • Publication number: 20110124901
    Abstract: A process is disclosed for producing organic nitriles such as Acetonitrile or Hydrogen Cyanide, in which yields may exceed 90%, undesirable by-products are not produced, and handling of ammonia gas is avoided. In one aspect, a process includes preparing a feed including ammonium salts and water; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst. The catalyst may advantageously include molybdenum on a silica or silica alumina support. The feed may be ammonium acetate in water with about 50 wt % ammonium acetate and the balance water or ammonium formate in water. In another aspect, a process includes preparing a feed including ammonium hydroxide and acetic acid; introducing the feed into a reactor containing a catalyst; and heating the feed in the presence of the catalyst.
    Type: Application
    Filed: November 20, 2009
    Publication date: May 26, 2011
    Inventors: Anil Oroskar, Paul Roman Kurek, Asha Oroskar