Patents by Inventor Anil Saksena

Anil Saksena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides as NS3-serine protease inhibitors of hepatitis C virus
    Patent number: 7595299
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: September 29, 2009
    Assignees: Schering Corporation, Dendreon Corporation
    Inventors: Anil Saksena, Viyyoor M. Girijavallabhan, Stephane L. Bogen, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Yi-Tsung Liu, Tin-Yau Chan, Zhaoning Zhu, Ashok Arasappan, Kevin X. Chen, Srikanth Venkatraman, Tejal Parekh, Patrick A. Pinto, Bama Santhanam, F. George Njoroge, Ashit K. Ganguly, Henry A. Vaccaro, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura
  • 17?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7485645
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: August 9, 2007
    Date of Patent: February 3, 2009
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Yi-Tsung Liu, Ronald J. Doll, Anil Saksena, Viyyoor M. Girijavallabhan, Jonathan A. Pachter
  • 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 INHIBITORS FOR THE TREATMENT OF ANDROGEN DEPENDENT DISEASES
    Publication number: 20080004248
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: August 9, 2007
    Publication date: January 3, 2008
    Inventors: Timothy Guzi, Yi-Tsung Liu, Ronald Doll, Anil Saksena, Viyyoor Girijavallabhan, Jonathan Pachter
  • 17?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7271175
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: February 23, 2006
    Date of Patent: September 18, 2007
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Yi-Tsung Liu, Ronald J. Doll, Anil Saksena, Viyyoor Girijavallabhan, Jonathan A. Pachter
  • Novel inhibitors of Hepatitis C virus NS3 protease
    Publication number: 20070142301
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 21, 2007
    Inventors: Stephane Bogen, Weidong Pan, Sumei Ruan, Kevin Chen, Ashok Arasappan, Srikanth Venkatraman, Latha Nair, Mousumi Sannigrahi, Frank Bennett, Anil Saksena, F. Njoroge, Viyyoor Girijavallabhan
  • Novel compounds as inhibitors of hepatitis C virus NS3 serine protease
    Publication number: 20070142300
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 21, 2007
    Inventors: Ashok Arasappan, F. Njoroge, Angela Padilla-Acevedo, Kevin Chen, Frank Bennett, Mousumi Sannigrahi, Stephane Bogen, Srikanth Venkatraman, Edwin Jao, Anil Saksena, Viyyoor Girijavallabhan
  • Sulfur compounds as inhibitors of Hepatitis C virus NS3 serine protease
    Publication number: 20070042968
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: February 24, 2005
    Publication date: February 22, 2007
    Inventors: Frank Bennett, Raymond Lovey, Yuhua Huang, Siska Hendrata, Anil Saksena, Stephane Bogen, Yi-Tsung Liu, F. Njoroge, Srikanth Venkatraman, Kevin Chen, Mousumi Sannigrahi, Ashok Arasappan, Viyyoor Girijavallabhan, Francisco Velazquez
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20070032433
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: January 18, 2002
    Publication date: February 8, 2007
    Inventors: Anil Saksena, Viyyoor Girijavallabhan, Raymond Lovey, Edwin Jao, Frank Bennett, Jinping Mc Cormick, Haiyan Wang, Russell Pike, Stephane Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. Njoroge, Ashok Arasappan, Tejal Parekh, Ashit Ganguly, Kevin Chen, Srikanth Venkatraman, Henry Vaccaro, Patrick Pinto, Bama Santhanam, Scott Kemp, Odile Levy, Marguerita Lim-wilby, Susan Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang, Jesse Wong, Latha Nair
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20060205672
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: September 30, 2005
    Publication date: September 14, 2006
    Applicants: Schering Corporation, Dendreon Corporation
    Inventors: Anil Saksena, Viyyoor Girijavallabhan, Raymond Lovey, Edwin Jao, Frank Bennett, Jinping McCormick, Haiyan Wang, Russell Pike, Stephane Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. Njoroge, Ashok Arasappan, Tejal Parekh, Ashit Ganguly, Kevin Chen, Srikanth Venkatraman, Henry Vaccaro, Patrick Pinto, Bama Santhanam, Scott Kemp, Odile Levy, Marguerita Lim-Wilby, Susan Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • 17beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20060142338
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: February 23, 2006
    Publication date: June 29, 2006
    Inventors: Timothy Guzi, Yi-Tsung Liu, Ronald Doll, Anil Saksena, Viyyoor Girijavallabhan, Jonathan Pachter
  • 17 ?-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Patent number: 7053091
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17?-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17?-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: May 30, 2006
    Assignee: Schering Corporation
    Inventors: Timothy J. Guzi, Yi-Tsung Liu, Ronald J. Doll, Anil Saksena, Viyyoor M. Girijavallabhan, Jonathan A. Pachter
  • 17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20060069103
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Application
    Filed: November 14, 2005
    Publication date: March 30, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Alan Mallams, Jocelyn Rivera, Ronald Doll, Viyyoor Girijavallabhan, Jonathan Pachter, Yi-Tsung Liu, Anil Saksena
  • 17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20060014755
    Abstract: There are disclosed compounds of the formula (I): prodrugs thereof, or pharmaceutically acceptable salts of the compounds or of said prodrugs which are useful as inhibitors of Type 3 17?-Hydroxysteroid Dehydrogenase. Also disclosed: are pharmaceutical compositions containing said compounds and their use for the treatment or prevention of androgen dependent diseases.
    Type: Application
    Filed: January 28, 2005
    Publication date: January 19, 2006
    Inventors: Timothy Guzi, Kamil Paruch, Alan Mallams, Jocelyn Rivera, Ronald Doll, Viyyoor Girijavallabhan, Jonathan Pachter, Yi-Tsung Liu, Anil Saksena
  • Novel inhibitors of hepatitis C virus NS3 protease
    Publication number: 20050267043
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: February 24, 2005
    Publication date: December 1, 2005
    Inventors: Stephane Bogen, Weidong Pan, Sumei Ruan, Kevin Chen, Ashok Arasappan, Srikanth Venkatraman, Latha Nair, Mousumi Sannigrahi, Frank Bennett, Anil Saksena, F. Njoroge, Viyyoor Girijavallabhan
  • Novel compounds as inhibitors of hepatitis C virus NS3 serine protease
    Publication number: 20050245458
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: February 24, 2005
    Publication date: November 3, 2005
    Inventors: Ashok Arasappan, F. Njoroge, Angela Padilla-Acevedo, Kevin Chen, Frank Bennett, Mousumi Sannigrahi, Stephane Bogen, Srikanth Venkatraman, Edwin Jao, Anil Saksena, Viyyoor Girijavallabhan
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20050176648
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: March 24, 2005
    Publication date: August 11, 2005
    Applicant: Schering-Plough Corporation
    Inventors: Anil Saksena, Viyyoor Girijavallabhan, Stephane Bogen, Raymond Lovey, Edwin Jao, Frank Bennett, Jinping McCormick, Haiyan Wang, Russell Pike, Yi-Tsung Liu, Tin-Yau Chan, Zhaoning Zhu, Ashok Arasappan, Kevin Chen, Srikanth Venkatraman, Tejal Parekh, Patrick Pinto, Bama Santhanam, F. Njoroge, Ashit Ganguly, Henry Vaccaro, Scott Kemp, Odile Levy, Marguerita Lim-Wilby, Susan Tamura
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20050059606
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such peptides as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: September 3, 2004
    Publication date: March 17, 2005
    Applicants: Dendreon Corporation, Schering Corporation
    Inventors: Anil Saksena, Viyyoor Girijavallabhan, Raymond Lovey, Edwin Jao, Ashok Arasappan, Tejal Parekh, Patrick Pinto, Frank Bennett, Jinping McCormick, Haiyan Wang, Russell Pike, Stephane Bogen, Yi-Tsung Liu, F. Njoroge, Ashit Ganguly, Terence Brunck, Scott Kemp, Odile Levy, Marguerita Lim-Wilby
  • Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties
    Patent number: 6846802
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: January 25, 2005
    Assignee: Schering Corporation
    Inventors: Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Tejal Parekh, Haining Gu, George F. Njoroge, Viyyoor Moopil Girijavallabhan, Ashit Ganguly, Anil Saksena, Edwin Jao, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison, Bancha Vibulbhan
  • Ribavirin-interferon alfa combination therapy for eradicating detectable HCV-RNA in patients having chronic hepatitis C infection
    Publication number: 20050004053
    Abstract: Ribavirin derivatives represented by the formula V, pharmaceutical compositions containing them as well as the use of the ribavirin derivatives represented by the formula V for the preparation of a medicament for the treatment of susceptible viral infections, for example, chronic hepatitis C infections administrating, the ribavirin derivatives being represented by formula V are disclosed.
    Type: Application
    Filed: July 6, 2004
    Publication date: January 6, 2005
    Inventors: Ashit Ganguly, Jinping McCormick, Raymond Lovey, Frank Bennett, Anil Saksena, Viyyoor Girijavallabhan
  • 17 Beta-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
    Publication number: 20040138226
    Abstract: In its many embodiments, the present invention provides a novel class of compounds as inhibitors of type 3 17&bgr;-hydroxysteroid dehydrogenase, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with type 3 17&bgr;-hydroxysteroid dehydrogenase using such compounds or pharmaceutical compositions.
    Type: Application
    Filed: December 15, 2003
    Publication date: July 15, 2004
    Applicant: SCHERING CORPORATION
    Inventors: Timothy J. Guzi, Yi-Tsung Liu, Ronald J. Doll, Anil Saksena, Viyyoor M. Girijavallabhan, Jonathan A. Pachter