Abstract: Structures including multiple semiconductor devices and methods of forming same. The structure comprises a first device structure including a first well and a second well in a semiconductor substrate, a second device structure including a doped region in the semiconductor substrate, and a first high-resistivity region in the semiconductor substrate. The first well has a first conductivity type, the second well has a second conductivity type opposite to the first conductivity type, and the first well adjoins the second well to define a p-n junction. The doped region of the second device structure has the first conductivity type or the second conductivity type. The high-resistivity region has a higher electrical resistivity than the semiconductor substrate, and the high-resistivity region is positioned between the first device structure and the second device structure.

Abstract: Provided are methods and kits for detecting an extrachromosomal circular DNA (eccDNA) in a biological sample. In some embodiments, the method comprises treating the biological sample to produce a tagged linearized fragment of genomic DNA; and determining whether the tagged linearized fragment is derived from an eccDNA to thereby detect the eccDNA. In some embodiments, the treating of the biological sample to produce a tagged linearized fragment of genomic DNA comprises treating the biological sample with an insertional enzyme complex to produce a tagged linearized fragment of genomic DNA.

Abstract: The present disclosure provides a method for providing cost efficient probable accommodation facilities in each of one or more area clusters. The method includes a first step to receive a first set of data associated with a plurality of organizations at a cluster identification system. The method includes another step to fetch a second set of data associated with a plurality of competitors. The method includes yet another step to obtain a set of rules associated with a plurality of parameters. The method includes yet another step to perform analysis of the first set of data, the second set of data, and the set of rules in real-time to identify the one or more area clusters in the geographical region based on the analysis of the first set of data and the second set of data with facilitation of the set of rules in real-time.

Abstract: The present disclosure provides a method for providing cost efficient probable accommodation facilities in each of one or more area clusters. The method includes a first step to receive a first set of data associated with a plurality of organizations at a cluster identification system. The method includes another step to fetch a second set of data associated with a plurality of competitors. The method includes yet another step to obtain a set of rules associated with a plurality of parameters. The method includes yet another step to perform analysis of the first set of data, the second set of data, and the set of rules in real-time to identify the one or more area clusters in the geographical region based on the analysis of the first set of data and the second set of data with facilitation of the set of rules in real-time.

Abstract: A method and an electronic device for managing notifications in a notification panel. The method includes receiving a notification associated with an application. Further, the method includes assigning the notification to a user defined group based on a plurality of parameters. Further, the method includes displaying, in the notification panel of the electronic device, a graphical element corresponding to the user defined group. Further, the method includes detecting a first user input, the first user input including a user selection of the graphical element, detecting a second user input, and applying an action to the notification based on the first user input and the second user input.

Abstract: Analysis of over 50 short RNA libraries revealed that tRFs are present in all human cell lines and exist in mice, flies, worms, and yeasts. Specific tRNA genes yield tRFs generated by cleavage at sites conserved across different cells within a species, and all three potential tRFs from a given tRNA gene were not always present or equally abundant. tRF-1 and -3 were highly abundant in the cytoplasm, while tRF-5 were mostly in the nucleus. tRF-5 and -3 were found in adult mouse tissues, tRF-1 were relatively rare in adult tissues but in greater amounts in mouse embryos and embryonic stem cells. Several tRF-1 sequences were conserved between mice and humans and expression was tissue-specific. tRFs are shown to be markers for cancer. For example greater amounts of tRF-1 were found in B cell malignancies compared to normal B cell, and tRF-5 and -3 were at higher levels in lung cancer compared to normal lung.

Abstract: The present invention provides a powerful technique based on ultra high-throughput sequencing that finds structural aberrations of chromosomes and defines breakpoints. It is disclosed herein that, Anchored ChromPET, a technique to capture and interrogate targeted sequences in the genome, is a cost-effective means to identify chromosomal aberrations and define breakpoints. Using this method, we defined the BCR-ABL1 translocation DNA breakpoint to a base-pair resolution in Philadelphia chromosome positive cell lines and patient cells. This DNA-based method is highly sensitive and can detect signal using samples from which it is hard to obtain RNA or cells where the RNA expression has been silenced. These data demonstrate that ChromPET is a cost-effective and powerful technology that can identify and follow the appearance of chromosomal aberrations in various organisms, including, but not limited to, humans.

Abstract: A unique test pattern is used for measuring timing parameters of RGBHV analog video signals. For horizontal timing a horizontal line includes within an active video region left and right portions at a first level and a central portion at a second level, the left, right and central portions having a defined percentage relationship to the number of pixels of the horizontal line within the active video region. Also optionally included are left and right border portions just prior to and just after the left and right portions respectively. Measurements are done in pixels for the horizontal line from a horizontal sync pulse to each transition of the unique test pattern, and the horizontal timing parameters are derived from such measurements.

Abstract: A unique test pattern is used for measuring timing parameters of RGBHV analog video signals. For horizontal timing a horizontal line includes within an active video region left and right portions at a first level and a central portion at a second level, the left, right and central portions having a defined percentage relationship to the number of pixels of the horizontal line within the active video region. Also optionally included are left and right border portions just prior to and just after the left and right portions respectively. Measurements are done in pixels for the horizontal line from a horizontal sync pulse to each transition of the unique test pattern, and the horizontal timing parameters are derived from such measurements.

Abstract: The invention relates to the use of geminin and/or Orc3N molecules for inhibiting viral replication. Use of the molecules and related molecules in the prevention and treatment of viral infections, such as papillomavirus infections, polyomavirus infections, and herpesvirus infections, such as Epstein-Barr virus (EBV) infections, are described.

Abstract: The invention relates to the use of geminin and/or Orc3N molecules for inhibiting viral replication. Use of the molecules and related molecules in the prevention and treatment of viral infections, such as papillomavirus infections, polyomavirus infections, and herpesvirus infections, such as Epstein-Barr virus (EBV) infections, are described.