Abstract: Polypeptides, proteins, and chimeric antigen receptors (CARs) that specifically bind to human mesothelin582-598 (IP-NGYLVLDLSMQEALS) (SEQ ID NO: 1) are disclosed. Anti-mesothelin binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and conjugates relating to the poly peptides, proteins, and CARS are disclosed. Methods of reducing mesothelin shed from cell membranes, methods of detecting the presence of cancer, and methods of treating or preventing cancer are also disclosed.

Abstract: The present invention relates to a method for the manufacture of a coated steel sheet comprising the following successive steps: A. the coating of the steel sheet with a first coating consisting of nickel and having a thickness between 600 nm and 1400 nm, the steel sheet having the following composition in weight: 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration, B. the recrystallization annealing at a temperature between 820 to 1200° C., C. the coating with a second coating based on zinc not comprising nickel.

Abstract: The present invention relates to a method for the manufacture of a galvannealed steel sheet including the steps of A.) coating of the steel sheet with a first coating consisting of nickel and having a thickness between 150 nm and 650 nm, the steel sheet having the following composition in weight percentage 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%., the remainder of the composition is made up of iron and inevitable impurities resulting from the elaboration, B.) annealing of the coated steel sheet being annealed at a temperature between 600 to 1200° C., C.) coating of the steel sheet obtained in step B.) with a second coating based on zinc and D.) an alloying heat treatment to form a galvannealed steel sheet.

Abstract: Galvannealed steel sheet having a steel substrate coated with a first alloy layer with iron and nickel directly topped by a second alloy layer based on zinc, the first and second alloyed layers being alloyed through diffusion such that the second alloy layer includes from 5 to 15 wt. % of iron, from 0 to 15 wt. % of nickel, a balance being zinc.

Abstract: A method for producing a zinc or zinc-alloy coated steel sheet with a tensile strength higher than 900 MPa, for the fabrication of resistance spot welds containing in average not more than two Liquid Metal Embrittlement cracks per weld having a depth of 100 ?m or more, with steps of providing a cold-rolled steel sheet, heating cold-rolled steel sheet up to a temperature T1 between 550° C. and Ac1+50° C. in a furnace zone with an atmosphere (A1) containing from 2 to 15% hydrogen by volume, so that the iron is not oxidized, then adding in the furnace atmosphere, water steam or oxygen with an injection flow rate Q higher than (0.07%/h×?), ? being equal to 1 if said element is water steam or equal to 0.52 if said element is oxygen, at a temperature T?T1, so to obtain an atmosphere (A2) with a dew point DP2 between ?15° C. and the temperature Te of the iron/iron oxide equilibrium dew point, then heating the sheet from temperature T1 up to a temperature T2 between 720° C. and 1000° C.

Abstract: A method and activity recognition system for recognising activities in surrounding environment for controlling navigation of an autonomous vehicle is disclosed. The activity recognition system receives first data feed from neuromorphic event-based camera and second data feed from frame-based RGB video camera. The first data feed comprises high-speed temporal information encoding motion associated with change in surrounding environment at each spatial location, and second data feed comprises spatio-temporal data providing scene-level contextual information associated with surrounding environment. An adaptive sampling of second data feed is performed with respect to foreground activity rate based on amount of foreground motion encoded in first data feed. Further, the activity recognition system recognizes activities associated with at least one object in surrounding environment by identifying correlation between both data feed by using two-stream neural network model.

Abstract: The present invention relates to a method for the manufacture of a galvannealed steel sheet including the steps of A.) coating of the steel sheet with a first coating consisting of nickel and having a thickness between 150 nm and 650 nm, the steel sheet having the following composition in weight percentage 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr s 1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%., the remainder of the composition is made up of iron and inevitable impurities resulting from the elaboration, B.) annealing of the coated steel sheet being annealed at a temperature between 600 to 1200° C., C.) coating of the steel sheet obtained in step B.) with a second coating based on zinc and D.) an alloying heat treatment to form a galvannealed steel sheet.

Abstract: A method for producing a high-strength steel sheet having high ductility, formability and weldability includes providing a cold-rolled sheet, with a composition containing: 0.15% ?C?0.23%, 1.4% ?Mn?2.6%, 0.6% ?Si?1.3%, with C+Si/10?0.30%, 0.4% ?Al?1.0%, with Al?6(C+Mn/10)?2.5%, 0.010% ?Nb?0.035%, 0.1% ?Mo?0.5%, annealing the sheet at 860° C.-900° C. to obtain a structure consisting of at least 90% austenite and at least 2% intercritical ferrite, quenching to a temperature between Ms-10° C. and Ms-60° C. at a rate Vc higher than 30° C./s, heating to a temperature PT between 410° C. and 470° C. for 60 s to 130 s, hot-dip coating the sheet, and cooling to room temperature. The microstructure includes 45% to 68% of martensite, consisting of 85% to 95% partitioned martensite having a C content of at most 0.45%, and fresh martensite; 10% to 15% retained austenite; 2% to 10% intercritical ferrite; 20% to 30% lower bainite.

Abstract: A steel sheet coated with a coating comprising from 10 to 40% of nickel, the balance being zinc, such steel sheet having a microstructure comprising from 1 to 50% of residual austenite, from 1 to 60% of martensite and optionally at least one element chosen from: bainite, ferrite, cementite and pearlite, and the following chemical composition in weight: 0.10<C<0.50%, 1.0<Mn<5.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0% and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.005%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration.

Abstract: The present invention relates to a method for the manufacture of a galvannealed steel sheet including the steps of A.) coating of the steel sheet with a first coating consisting of nickel and having a thickness between 150 nm and 650 nm, the steel sheet having the following composition in weight percentage 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%, the remainder of the composition is made up of iron and inevitable impurities resulting from the elaboration, B.) annealing of the coated steel sheet being annealed at a temperature between 600 to 1200° C., C.) coating of the steel sheet obtained in step B.) with a second coating based on zinc and D.) an alloying heat treatment to form a galvannealed steel sheet.

Abstract: A method for producing a zinc or zinc-alloy coated steel sheet with a tensile strength higher than 900 MPa, for the fabrication of resistance spot welds containing in average not more than two Liquid Metal Embrittlement cracks per weld having a depth of 100 ?m or more, with steps of providing a cold-rolled steel sheet, heating cold-rolled steel sheet up to a temperature T1 between 550° C. and Ac1+50° C. in a furnace zone with an atmosphere (A1) containing from 2 to 15% hydrogen by volume, so that the iron is not oxidized, then adding in the furnace atmosphere, water steam or oxygen with an injection flow rate Q higher than (0.07%/h×?), ? being equal to 1 if said element is water steam or equal to 0.52 if said element is oxygen, at a temperature T?T1, so to obtain an atmosphere (A2) with a dew point DP2 between ?15° C. and the temperature Te of the iron/iron oxide equilibrium dew point, then heating the sheet from temperature T1 up to a temperature T2 between 720° C. and 1000° C.

Abstract: Method for the manufacture of a galvannealed steel sheet includes the following steps: A) the provision of a pre-coated steel sheet coated with a first coating comprising iron and nickel, such steel sheet having the following chemical composition in weight percent 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<2.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0% and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.005%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration, B) the thermal treatment of such pre-coated steel sheet at a temperature between 600 to 1000° C., C) the hot-dip coating of the steel sheet obtained in step B) with a second coating based on zinc and D) an alloying treatment to form a galvannealed steel sheet.

Abstract: The present invention relates to a method for the manufacture of a coated steel sheet comprising the following successive steps: A. the coating of the steel sheet with a first coating consisting of nickel and having a thickness between 600 nm and 1400 nm, the steel sheet having the following composition in weight: 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%, the remainder of the composition making up of iron and inevitable impurities resulting from the elaboration, B. the recrystallization annealing at a temperature between 820 to 1200° C., C. the coating with a second coating based on zinc not comprising nickel.

Abstract: A sensor having a distal end and an intermediate region adjacent to the distal end is provided. The sensor includes an insulator base substrate, sensor electrodes over the insulator base substrate, an electrode lead pattern over the insulator base substrate, wherein the electrode lead pattern includes electrode leads configured for contact with the sensor electrodes, and wherein the electrode leads extend completely across the intermediate region in a longitudinal direction, and a structural backing layer over the electrode lead pattern and insulator base substrate; wherein a side edge of the structural backing layer over the electrode lead pattern extends completely across the structural backing layer in the longitudinal direction.

Abstract: A method and activity recognition system for recognising activities in surrounding environment for controlling navigation of an autonomous vehicle is disclosed. The activity recognition system receives first data feed from neuromorphic event-based camera and second data feed from frame-based RGB video camera. The first data feed comprises high-speed temporal information encoding motion associated with change in surrounding environment at each spatial location, and second data feed comprises spatio-temporal data providing scene-level contextual information associated with surrounding environment. An adaptive sampling of second data feed is performed with respect to foreground activity rate based on amount of foreground motion encoded in first data feed. Further, the activity recognition system recognizes activities associated with at least one object in surrounding environment by identifying correlation between both data feed by using two-stream neural network model.

Abstract: Method for the manufacture of a coated steel sheet including the following step of A) the provision of a pre-coated steel sheet coating with a first coating including iron and nickel, B) the thermal treatment of such pre-coated steel sheet at a temperature between 600 and 1000° C., and C) the coating of the steel sheet obtained in step B) with a second coating based on zinc.

Abstract: Sensors and methods for manufacturing sensors are provided. An exemplary method for manufacturing a sensor includes forming an electrode lead pattern over an insulator base substrate. Further, the method includes forming a structural backing layer over the electrode lead pattern and insulator base substrate. Also, the method includes performing a cutting process to cut through the structural backing layer to form a structural backing over the electrode lead pattern.

Abstract: Sensors and methods for manufacturing sensors are provided. An exemplary method for manufacturing a sensor includes forming an electrode lead pattern over an insulator base substrate. Further, the method includes forming a structural backing layer over the electrode lead pattern and insulator base substrate. Also, the method includes performing a cutting process to cut through the structural backing layer to form a structural backing over the electrode lead pattern.

Abstract: A method may include generating a first database query to retrieve user profiles from a database. The user profiles may include a first attribute and a second attribute associated with a plurality of users. Reference data may be generated based on the user profiles. The reference data may include matrix representations of the user profiles. A clustering technique may be applied to the reference data in order to determine that a first user is similar to a second user with respect to the first attribute. In response to determining that the first user is similar to the second user, a second database query may be generated to retrieve a user profile of the first user from the database. A first recommendation for the second user may be determined based on the user profile of the first user. The first recommendation may include the second attribute of the first user.

Abstract: The present invention relates to a method for the manufacture of a galvannealed steel sheet including the steps of A.) coating of the steel sheet with a first coating consisting of nickel and having a thickness between 150 nm and 650 nm, the steel sheet having the following composition in weight percentage 0.10<C<0.40%, 1.5<Mn<3.0%, 0.7<Si<3.0%, 0.05<Al<1.0%, 0.75<(Si+Al)<3.0%, and on a purely optional basis, one or more elements such as Nb?0.5%, B?0.010%, Cr?1.0%, Mo?0.50%, Ni?1.0%, Ti?0.5%., the remainder of the composition is made up of iron and inevitable impurities resulting from the elaboration, B.) annealing of the coated steel sheet being annealed at a temperature between 600 to 1200° C., C.) coating of the steel sheet obtained in step B.) with a second coating based on zinc and D.) an alloying heat treatment to form a galvannealed steel sheet.