Patents by Inventor Anita A. Mathias

Anita A. Mathias has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of solid carrier particles to improve the processability of a pharmaceutical agent
    Patent number: 10039718
    Abstract: The invention provides a composition comprising, a compound of formula (I): or a pharmaceutically acceptable salt thereof and a plurality of solid carrier particles, as well as methods for using the composition to inhibit the activity of cytochrome P-450.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: August 7, 2018
    Assignee: Gilead Sciences, Inc.
    Inventors: Joanna M. Koziara, Mark M. Menning, Robert G. Strickley, Richard Yu, Brian P. Kearney, Anita A. Mathias
  • METHOD OF TREATING A VIRAL INFECTION USING ELVITEGRAVIR COMBINATIONS
    Publication number: 20170136000
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by coadministering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with lopinavir or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 19, 2016
    Publication date: May 18, 2017
    Inventors: Brian P. KEARNEY, Anita A. MATHIAS
  • METHOD OF TREATING A VIRAL INFECTION USING ELVITEGRAVIR COMBINATIONS
    Publication number: 20170136001
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: October 19, 2016
    Publication date: May 18, 2017
    Inventors: Brian P. KEARNEY, Anita A. MATHIAS, Srinivasan RAMANATHAN
  • METHOD OF TREATING A VIRAL INFECTION USING ELVITEGRAVIR COMBINATIONS
    Publication number: 20140343062
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by coadministering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with lopinavir or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Brian P. KEARNEY, Anita A. MATHIAS
  • METHOD OF TREATING A VIRAL INFECTION USING ELVITEGRAVIR COMBINATIONS
    Publication number: 20140343063
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: May 19, 2014
    Publication date: November 20, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Brian P. KEARNEY, Anita A. MATHIAS, Srinivasan RAMANATHAN
  • THERAPEUTIC COMPOSITIONS AND THE USE THEREOF
    Publication number: 20110009411
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by coadministering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with lopinavir or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 26, 2008
    Publication date: January 13, 2011
    Applicant: Gilead Sciences ,Inc.
    Inventors: Brian P. Kearney, Anita A. Mathias
  • THERAPEUTIC COMPOSITIONS AND THE USE THEREOF
    Publication number: 20100331331
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 26, 2008
    Publication date: December 30, 2010
    Applicant: ThERAPEUTIC COMPOSITONS AND USE THEREOF
    Inventors: Brian P. Kearney, Anita A. Mathias, Srinivasan Ramanathan
  • USE OF SOLID CARRIER PARTICLES TO IMPROVE THE PROCESSABILITY OF A PHARMACEUTICAL AGENT
    Publication number: 20090324729
    Abstract: The invention provides a composition comprising, a compound of formula (I): or a pharmaceutically acceptable salt thereof and a plurality of solid carrier particles, as well as methods for using the composition to inhibit the activity of cytochrome P-450.
    Type: Application
    Filed: May 1, 2009
    Publication date: December 31, 2009
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Joanna M. Koziara, Mark M. Menning, Reza Oliyai, Robert G. Strickley, Richard Yu, Brian P. Kearney, Anita A. Mathias
  • THERAPEUTIC COMPOSITIONS AND METHODS
    Publication number: 20090093482
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by coadministering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with lopinavir or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 26, 2008
    Publication date: April 9, 2009
    Applicant: Gilead Sciences, Inc.
    Inventors: Brian P. Kearney, Anita A. Mathias
  • THERAPEUTIC COMPOSITIONS AND METHODS
    Publication number: 20090093467
    Abstract: The invention includes methods, compositions, and kits useful for treating a viral infection by administering 6-(3-chloro-2-fluorobenzyl)-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or a pharmaceutically acceptable salt thereof, with atazanavir or a pharmaceutically acceptable salt thereof, and optionally with a compound that inhibits cytochrome P-450, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: June 26, 2008
    Publication date: April 9, 2009
    Applicant: Gilead Sciences, Inc.
    Inventors: Brian P. Kearney, Anita A. Mathias, Srinivasan Ramanathan