Patents by Inventor Anita B. Hjelmeland

Anita B. Hjelmeland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9731032
    Abstract: Aptamers consisting of a single stranded nucleic acids having 100 nucleotides or less that specifically binds to tumor initiating cancer cells are described. The aptamers can be identified by screening a large pool of randomly generated aptamers to obtain a discrete set of aptamers that specifically bind to tumor initiating cancer cells, such as those found in brain cancer or glioblastoma. The aptamers can also be linked or complexed with anticancer agents or imaging agents for use in therapy or diagnosis.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: August 15, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Jeremy N. Rich, Youngmi Kim, Anita B. Hjelmeland
  • Publication number: 20170165376
    Abstract: Aptamers consisting of a single stranded nucleic acids having 100 nucleotides or less that specifically binds to tumor initiating cancer cells are described. The aptamers can be identified by screening a large pool of randomly generated aptamers to obtain a discrete set of aptamers that specifically bind to tumor initiating cancer cells, such as those found in brain cancer or glioblastoma. The aptamers can also be linked or complexed with anticancer agents or imaging agents for use in therapy or diagnosis.
    Type: Application
    Filed: February 4, 2014
    Publication date: June 15, 2017
    Inventors: Jeremy N. Rich, Youngmi Kim, Anita B. Hjelmeland
  • Publication number: 20150366996
    Abstract: Aptamers consisting of a single stranded nucleic acids having 100 nucleotides or less that specifically binds to tumor initiating cancer cells are described. The aptamers can be identified by screening a large pool of randomly generated aptamers to obtain a discrete set of aptamers that specifically bind to tumor initiating cancer cells, such as those found in brain cancer or glioblastoma. The aptamers can also be linked or complexed with anticancer agents or imaging agents for use in therapy or diagnosis.
    Type: Application
    Filed: February 4, 2014
    Publication date: December 24, 2015
    Inventors: Jeremy N. Rich, Youngmi Kim, Anita B. Hjelmeland