Patents by Inventor Anitra Wolf

Anitra Wolf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric fusion proteins and related compositions and methods
    Patent number: 8822642
    Abstract: Compositions and methods relating to soluble dimeric proteins are disclosed. The dimeric proteins comprise first and second polypeptide fusions linked via a dimerizing domain, each polypeptide fusion comprising first and second monomer domains corresponding to a cytokine or an extracellular domain of a cell-surface receptor. The monomer domains may be positioned amino terminal and carboxyl terminal to the dimerizing domain. Alternatively, the monomer domains may be positioned in tandem, either carboxyl terminal or amino terminal to the dimerizing domain. The dimeric proteins are useful in methods for therapy, diagnosis, and research.
    Type: Grant
    Filed: June 7, 2011
    Date of Patent: September 2, 2014
    Assignee: ZymoGenetics, Inc.
    Inventors: Steven D. Levin, Margaret D. Moore, Craig D. Ostrander, Katherine E. Lewis, David W. Taft, Robert J. Rosler, Anitra Wolf, Megan M. Lantry
  • DIMERIC FUSION PROTEINS AND RELATED COMPOSITIONS AND METHODS
    Publication number: 20130095102
    Abstract: Compositions and methods relating to soluble dimeric proteins are disclosed. The dimeric proteins comprise first and second polypeptide fusions linked via a dimerizing domain, each polypeptide fusion comprising first and second monomer domains corresponding to a cytokine or an extracellular domain of a cell-surface receptor. The monomer domains may be positioned amino terminal and carboxyl terminal to the dimerizing domain. Alternatively, the monomer domains may be positioned in tandem, either carboxyl terminal or amino terminal to the dimerizing domain. The dimeric proteins are useful in methods for therapy, diagnosis, and research.
    Type: Application
    Filed: June 7, 2011
    Publication date: April 18, 2013
    Applicant: ZymoGenetics, Inc.
    Inventors: Steven D. Levin, Margaret D. Moore, Craig D. Ostrander, Katherine E. Lewis, David W. Taft, Robert J. Rosler, Anitra Wolf, Megan M. Lantry
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20070087414
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: April 19, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20070078259
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: April 5, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20070065405
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: March 22, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20070065403
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: March 22, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Uses of humans zven proteins and polynucleotides
    Publication number: 20070065404
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: March 22, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Use of human Zven proteins and polynucleotides
    Publication number: 20070048258
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: March 1, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20070049526
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal function with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 12, 2006
    Publication date: March 1, 2007
    Inventors: Penny Thompson, Katherine Lewis, Stephen Jaspers, Richard Garcia, Robert West, Susan Holderman, Chung Chan, Paul Sheppard, Anitra Wolf
  • Compositions and uses of secreted polypeptide, Zsig98
    Publication number: 20060258586
    Abstract: The present invention provides methods of using Zsig98 polypeptides for treating intestinal motility disorders and improving gastrointestinal function, nutritient absorption, metabolism, and diabetes with Zsig98 polypeptides. The invention also provides methods for producing Zsig98 polynucleotides, polypeptides and antibodies.
    Type: Application
    Filed: May 5, 2006
    Publication date: November 16, 2006
    Inventors: Paul Sheppard, Stephen Jaspers, Michael Stamm, Anitra Wolf, Jacob Kennedy
  • Uses of human Zven proteins and polynucleotides
    Publication number: 20040162238
    Abstract: The present invention provides methods of using Zven1 and Zven2 polypeptides to increase chemokine production. The present invention also provides methods for treating intestinal motility disorders and improving gastrointestinal funciton with Zven1 and Zven2 polypeptides.
    Type: Application
    Filed: October 7, 2003
    Publication date: August 19, 2004
    Inventors: Penny J. Thompson, Katherine E. Lewis, Stephen R. Jaspers, Richard M. Garcia, Robert R. West, Susan D. Holderman, Chung Chan, Paul O. Sheppard, Anitra Wolf
  • Use of corticotroph-derived glycoprotein hormone to treat inflammation and potentiate glucocorticoid action
    Publication number: 20040138113
    Abstract: The use of corticotroph-derived glycoprotein hormone (CGH) to potentiate glucocorticoid action and to reduce glucocorticoid-induced adrenocortical suppression is described. CGH can be co-administered with glucocorticoids to enable a lower dosage of glucocorticoids to be used and to prevent or reduce glucocorticoid-induced side-effects. The invention additionally provides methods for the use of CGH as a replacement for glucocorticoids, or for treatment of a broad range of inflammatory states. Further provided are methods for purification of recombinant CGH.
    Type: Application
    Filed: June 10, 2003
    Publication date: July 15, 2004
    Inventors: James D. Kelly, Philippa J. Webster, Stacey R. Dillon, Shannon L. O'Hogan, Anitra Wolf