Patents by Inventor Anjali Pandey

Anjali Pandey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS AND COMPOSITIONS FOR ACHIEVING MAMMALIAN ENERGY BALANCE
    Publication number: 20170128410
    Abstract: Disclosed is a method of achieving optimal mammalian energy balance using forskolin on a particular physiological and developmental stage of the mammalian cellular system.
    Type: Application
    Filed: November 10, 2015
    Publication date: May 11, 2017
    Inventors: MUHAMMED MAJEED, Kalyanam Nagabhushanam, Sarang Bani, Anjali Pandey
  • Compounds and methods for purification of serine proteases
    Patent number: 9644195
    Abstract: Disclosed herein are compounds, compositions, methods and kits for purifying a serine protease and serine proteases purified with the compounds, compositions and methods.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: May 9, 2017
    Assignee: Portola Pharmaceuticals, Inc.
    Inventors: Anjali Pandey, Jack W. Rose
  • Method for the treatment of hypercholesterolemia
    Patent number: 9610273
    Abstract: Disclosed is a therapeutic management method of hypercholesterolemia in mammals. More specifically, the present invention relates to a method of reducing high levels of circulating cholesterol (hypercholesterolemia) in the blood stream of mammals, said method involving step of administering therapeutically effective amounts of Calebin A to said mammals to bring about the effects of (i) reducing the amount of total blood cholesterol levels; (ii) reducing the concentrations of low density lipoproteins (LDL) and very low density lipoproteins (VLDL); (iii) increasing the concentrations of high density lipoproteins (HDL) and (iv) reducing concentrations of serum triglycerides.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: April 4, 2017
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Anju Majeed, Sarang Bani, Anjali Pandey
  • COMPOSITION COMPRISING SCIRPUSIN A AND SCIRPUSIN B AND ANTI-OBESITY POTENTIAL THEREOF
    Publication number: 20170072003
    Abstract: Disclosed are methods of managing hypercholesterolemia using a composition of matter comprising the ethyl acetate fraction of the extract of Cyperus rotundus rhizomes standardized to contain 5% of total stilbenes.
    Type: Application
    Filed: July 19, 2016
    Publication date: March 16, 2017
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Douglas Kalman, Beena Bhat, Priti Vaidyanathan, Sarang Bani, Anjali Pandey, Suresh Karri
  • Inhibitors of syk and JAK protein kinases
    Patent number: 9579320
    Abstract: The present invention is directed to compounds of formula I-V and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: February 28, 2017
    Assignee: Portola Pharmaceuticals, Inc.
    Inventors: Zhaozhong J. Jia, Chandrasekar Venkataramani, Wolin Huang, Mukund Mehrotra, Yonghong Song, Qing Xu, Shawn M. Bauer, Jack W. Rose, Brian Kane, Anjali Pandey
  • Bicyclic dihydropyridone kinase inhibitors
    Patent number: 9533986
    Abstract: Provided are bicyclic dihydropyridone compounds for inhibiting of JAK/Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibiting JAK/Syk kinase activity, and methods for treating conditions mediated at least in part by JAK/Syk kinase activity.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: January 3, 2017
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Anjali Pandey, Yonghong Song, Qing Xu
  • BENZAMIDES AND NICOTINAMIDES AS SYK MODULATORS
    Publication number: 20160318852
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
    Type: Application
    Filed: May 10, 2016
    Publication date: November 3, 2016
    Inventors: Zhaozhong J. Jia, Yonghong Song, Qing Xu, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Bicyclic oxa-lactam kinase inhibitors
    Patent number: 9469654
    Abstract: Provided are bicyclic oxa-lactam compounds of formula I: and pharmaceutically acceptable salts thereof which are inhibitors of JAK/Syk kinase. The present disclosure is also directed to intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibiting JAK/Syk kinase activity, and methods for treating conditions mediated at least in part by JAK/Syk kinase activity.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: October 18, 2016
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Anjali Pandey, Yonghong Song, Qing Xu
  • Composition comprising scirpusin A and scirpusin B and anti-adipogenesis/anti-obesity potential thereof
    Patent number: 9387193
    Abstract: Disclosed is a composition comprising scirpusin A and scirpusin B and anti-obesity potential thereof. Also disclosed are methods of inhibiting adipogenesis using a composition comprising scirpusin A and scirpusin B. The present invention also disclosed methods of therapeutically managing obesity in mammals using a composition comprising scirpusin A and scirpusin B. Still further, the present invention also relates to a method of obtaining compositions comprising A. scirpusin A and scirpusin B and B. piceatannol and its dimers scirpusin A and scirpusin B through bioactivity guided fractionation of the rhizomes of Cyperus rotundus.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: July 12, 2016
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Douglas Kalman, Beena Bhat, Priti Vaidyanathan, Sarang Bani, Anjali Pandey
  • Benzamides and nicotinamides as Syk modulators
    Patent number: 9359375
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as Non Hodgkin's Lymphoma.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: June 7, 2016
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Zhaozhong J. Jia, Yonghong Song, Qing Xu, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Pyrazine kinase inhibitors
    Patent number: 9359308
    Abstract: Provided are pyrazine compounds of Formula (I) for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibition Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.
    Type: Grant
    Filed: November 23, 2012
    Date of Patent: June 7, 2016
    Assignee: PORTOLA PHARMACEUTICALS, INC.
    Inventors: Yonghong Song, Qing Xu, Zhaozhong J. Jia, Brian Kane, Shawn M. Bauer, Anjali Pandey
  • Anti-obesity potential of Calebin A
    Patent number: 9328330
    Abstract: The present invention discloses the potential of Calebin A in inhibiting adipogenesis and applications thereof in obesity management. The present invention elucidates the potential of Calebin A to favorably modulate biochemical markers associated with obesity. Notable biomodulatory properties of Calebin A include inhibiting leptin production, increasing adiponectin expression and inhibiting local (adipocyte) and systemic inflammation caused by pro-inflammatory cytokines Tumor Necrosis Factor (TNF-?), Interleukin-6 (IL-6) and Interleukin-1 (IL-1?).
    Type: Grant
    Filed: May 9, 2014
    Date of Patent: May 3, 2016
    Assignee: SAMI LABS LIMITED
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Anju Majeed, Bani Sarang, Anjali Pandey
  • CYCLOHEXANEDIAMINE COMPOUNDS AND METHODS FOR THEIR PREPARATION
    Publication number: 20160009694
    Abstract: The present invention provides processes for the preparation of cyclohexanediamine compounds of formula Ia and intermediates thereof. The compounds are useful as Syk kinase inhibitors and in various pharmaceutical compositions, and particularly useful for treating conditions mediated at least in part by Syk kinase activity.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 14, 2016
    Inventor: ANJALI PANDEY
  • Composition and method for the protection of articular cartilage
    Patent number: 9220703
    Abstract: The novel therapeutic potential of Calebin A and compositions thereof to prevent pathological damage to mammalian articular cartilage is disclosed.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: December 29, 2015
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Sarang Bani, Anjali Pandey
  • INHIBITION OF TISSUE FACTOR PATHWAY INHIBITOR WITH FACTOR XA DERIVATIVES
    Publication number: 20150352194
    Abstract: The present disclosure relates to compositions and methods for the treatment of bleeding disorders, such as hemophilia A, hemophilia B, von Willebrand (vWF) disease, and factor XII deficiency, by reducing the circulating concentration of tissue factor pathway inhibitor (TFPI), with a factor Xa derivative.
    Type: Application
    Filed: March 13, 2013
    Publication date: December 10, 2015
    Inventors: Genmin Lu, Uma Sinha, Mark Karbarz, Anjali Pandey, Pamela B. Conley
  • NICOTINAMIDES AS JAK KINASE MODULATORS
    Publication number: 20150353495
    Abstract: The present invention is directed to compounds of formula I and pharmaceutically acceptable salts, esters, and prodrugs thereof which are inhibitors of JAK kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition JAK kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by JAK kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.
    Type: Application
    Filed: June 29, 2015
    Publication date: December 10, 2015
    Inventors: Shawn M. BAUER, YONGHONG SONG, QING XU, JACK W. ROSE, ZHAOZHONG J. JIA, BRIAN KANE, WOLIN HUANG, ANJALI PANDEY, MUKUND MEHROTRA
  • Compounds and methods for purification of serine proteases
    Patent number: 9200268
    Abstract: Disclosed herein are compounds, compositions, methods and kits for purifying a serine protease and serine proteases purified with the compounds, compositions and methods.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 1, 2015
    Assignee: Portola Pharmaceuticals, Inc.
    Inventors: Anjali Pandey, Jack W. Rose
  • COMPOUNDS AND METHODS FOR PURIFICATION OF SERINE PROTEASES
    Publication number: 20150337285
    Abstract: Disclosed herein are compounds, compositions, methods and kits for purifying a serine protease and serine proteases purified with the compounds, compositions and methods.
    Type: Application
    Filed: May 27, 2015
    Publication date: November 26, 2015
    Inventors: Anjali Pandey, Jack W. Rose
  • METHOD FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA
    Publication number: 20150306060
    Abstract: Disclosed is a therapeutic management method of hypercholesterolemia in mammals. More specifically, the present invention relates to a method of reducing high levels of circulating cholesterol (hypercholesterolemia) in the blood stream of mammals, said method involving step of administering therapeutically effective amounts of Calebin A to said mammals to bring about the effects of (i) reducing the amount of total blood cholesterol levels; (ii) reducing the concentrations of low density lipoproteins (LDL) and very low density lipoproteins (VLDL); (iii) increasing the concentrations of high density lipoproteins (HDL) and (iv) reducing concentrations of serum triglycerides.
    Type: Application
    Filed: March 3, 2015
    Publication date: October 29, 2015
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Anju Majeed, Sarang Bani, Anjali Pandey
  • METHOD FOR THE TREATMENT OF HYPERCHOLESTEROLEMIA
    Publication number: 20150306059
    Abstract: Disclosed is a therapeutic management method of hypercholesterolemia in mammals. More specifically, the present invention relates to a method of reducing high levels of circulating cholesterol (hypercholesterolemia) in the blood stream of mammals, said method involving step of administering therapeutically effective amounts of Calebin A to said mammals to bring about the effects of (i) reducing the amount of total blood cholesterol levels; (ii) reducing the concentrations of low density lipoproteins (LDL) and very low density lipoproteins (VLDL); (iii) increasing the concentrations of high density lipoproteins (HDL) and (iv) reducing concentrations of serum triglycerides.
    Type: Application
    Filed: April 23, 2014
    Publication date: October 29, 2015
    Inventors: Muhammed Majeed, Kalyanam Nagabhushanam, Anju Majeed, Sarang Bani, Anjali Pandey