Patents by Inventor Anjan Chakrabarti
Anjan Chakrabarti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10508109Abstract: The present invention directs to a compound represented by formula (I).Type: GrantFiled: September 12, 2016Date of Patent: December 17, 2019Assignee: ONCOTHERAPY SCIENCE, INC.Inventors: Yo Matsuo, Shoji Hisada, Yusuke Nakamura, Anjan Chakrabarti, Manish Rawat, Sanjay Rai, Arvapalli Venkata Satyanarayana, Zhiyong Duan, Arindam Talukdar, Srinivas Ravula, Helene Decornez
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Patent number: 10093683Abstract: The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more compounds of Formula (I), and methods for using the compounds of Formula (I) for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.Type: GrantFiled: April 21, 2015Date of Patent: October 9, 2018Assignee: Merck Sharp & Dohme Corp.Inventors: Yeon-Hee Lim, Zhuyan Guo, Amjad Ali, Scott D. Edmondson, Weiguo Liu, Gioconda V. Gallo-Etienne, Heping Wu, Ying-Duo Gao, Andrew W. Stamford, Younong Yu, Nancy J. Kevin, Rajan Anand, Deyou Sha, Santhosh F. Neelamkavil, Zahid Hussain, Puneet Kumar, Remond Moningka, Joseph L. Duffy, Jiayi Xu, Yu Jiang, Anjan Chakrabarti, Hiroki Sone
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Publication number: 20180273529Abstract: The present invention directs to a compound represented by formula (I).Type: ApplicationFiled: September 12, 2016Publication date: September 27, 2018Inventors: YO MATSUO, Shoji Hisada, Yusuke Nakamura, Anjan Chakrabarti, Manish Rawat, Sanjay Rai, Arvapalli Venkata Satyanarayana, Zhiyong Duan, Arindam Talukdar, Srinivas Ravula, Helene Decornez
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Patent number: 9586967Abstract: A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong Axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for Axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.Type: GrantFiled: November 6, 2014Date of Patent: March 7, 2017Assignee: ONO PHARMACEUTICAL CO., LTD.Inventors: Takayuki Inukai, Jun Takeuchi, Tomoko Yasuhiro, Mark Allan Wolf, Vijay Dattaram Pawar, Anjan Chakrabarti, Santhosh Kumar Chittimalla
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Publication number: 20170044183Abstract: The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.Type: ApplicationFiled: April 21, 2015Publication date: February 16, 2017Applicant: Merck Sharp & Dohme Corp.Inventors: Yeon-Hee Lim, Zhuyan Guo, Amjad Ali, Scott D. Edmondson, Weiguo Liu, Giocanda V. Gallo-Etienne, Heping Wu, Ying-Duo Gao, Andrew W. Stamford, Younong Yu, Nancy J. Kevin, Rajan Anand, Deyou Sha, Santhosh F. Neelamkavil, Zahid Hussain, Puneet Kumar, Remond Moningka, Joseph L. Duffy, Jiayi Xu, Yu Jiang, Anjan Chakrabarti, Hiroki Sone
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Publication number: 20160264579Abstract: A compound represented by the general formula (1) has a pyridone ring structure introduced into a pyrrolo pyrimidine skeleton, so that the compound has a strong Axl inhibitory activity. Consequently, the compound can be used as a therapeutic agent for Axl-related diseases including cancers such as acute myeloid leukemia, melanoma, breast cancer, pancreatic cancer, and glioma, kidney diseases, immune system diseases, and circulatory system diseases.Type: ApplicationFiled: November 6, 2014Publication date: September 15, 2016Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Takayuki INUKAI, Jun TAKEUCHI, Tomoko YASUHIRO, Mark Allan WOLF, Vijay Dattaram PAWAR, Anjan CHAKRABARTI, Santhosh Kumar CHITTIMALLA
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Publication number: 20160120863Abstract: Provided is a SLC2A class I transporter inhibitor compound for use in medicine, which compound comprises the following formula: wherein A and Z may be the same or different and are each independently selected from C, N, O and S; each X may be the same or different and is independently selected from C, N, O and S; R1 and R5 may be present or absent and may be the same or different and are each selected from H and a substituted or unsubstituted organic group; Z completes a ring with each X, each ring comprising from 3 to 8 ring atoms including the X, A, and Z, each ring atom being independently selected from C, N, O and S, and each ring atom being unsubstituted or independently substituted with H or a substituted or unsubstituted organic group; and wherein the bonds between all of the atoms in the rings including the X, A, and Z may independently be single bonds or double bonds, provided that when X or a ring atom is O or S the bonds to X are single bonds.Type: ApplicationFiled: May 22, 2014Publication date: May 5, 2016Inventors: Phillip Martin Cowley, Alan Wise, Thomas James Brown, Matthew Isherwood, Anjan Chakrabarti
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Publication number: 20130012685Abstract: The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.Type: ApplicationFiled: July 3, 2012Publication date: January 10, 2013Applicant: AFFYMAX, INC.Inventors: Christopher P. Holmes, Qun Yin, Genet Zemede, Ashok Bhandari, Yaohua S. Dong, David Tumelty, Guy Lalonde, Brian T. Frederick, Anjan Chakrabarti, Palani Balu, Peter J. Schatz, Nicholas C. Wrighton, William J. Dower
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Publication number: 20120165275Abstract: Compounds comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety are disclosed. Various linker moieties for use in these compounds are also disclosed, along methods for their synthesis.Type: ApplicationFiled: December 21, 2011Publication date: June 28, 2012Applicant: AFFYMAX, INC.Inventors: Christopher P. Holmes, Anjan Chakrabarti, Brian T. Frederick, Yijun Pan, Yaohua S. Dong, Ashok Bhandari
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Publication number: 20120157660Abstract: The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.Type: ApplicationFiled: August 18, 2010Publication date: June 21, 2012Applicant: AFFYMAX, INC.Inventors: Christopher P. Holmes, Qun Yin, Genet Zemede, Ashok Bhandari, David Tumelty, Guy Lalonde, Palani Balu, Peter J. Schatz, William J. Dower, Anjan Chakrabarti, Yaohua S. Dong, Brian T. Frederick, Nicholas C. Wrighton
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Patent number: 8106154Abstract: Compounds comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety are disclosed. Various linker moieties for use in these compounds are also disclosed, along methods for their synthesis.Type: GrantFiled: January 30, 2008Date of Patent: January 31, 2012Assignee: Affymax, Inc.Inventors: Christopher P. Holmes, Anjan Chakrabarti, Brian T. Frederick, Yijun Pan, Yaohua S. Dong, Ashok Bhandari
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Publication number: 20110282029Abstract: The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.Type: ApplicationFiled: December 10, 2010Publication date: November 17, 2011Applicant: AFFYMAX, INC.Inventors: Christopher P. Holmes, Qun Yin, Genet Zemede, Ashok Bhandari, Yaohua S. Dong, David Tumelty, Guy Lalonde, Brian T. Frederick, Anjan Chakrabarti, Palani Balu, Peter J. Schatz, Nicholas C. Wrighton, William J. Dower
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Publication number: 20090130225Abstract: The present invention provides macrolide derivatives, which can be used as antibacterial agents. Compounds described herein can be used for treating or preventing conditions caused by or contributed to by gram-positive, gram-negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Propionibeacterium, Bacillus, Enterobactericeae or any combination thereof. Also provided are processes for preparing compounds described herein, pharmaceutical compositions thereof, and methods of treating bacterial infections.Type: ApplicationFiled: November 21, 2006Publication date: May 21, 2009Inventors: Anjan Chakrabarti, Biswajit Das, Jitendra Sambhaji Jadhav, Dilip J. Upadhyay
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Publication number: 20090075916Abstract: This invention relates to 14-membered macrolide derivatives for treating or preventing acne vulgaris and associated inflammatory conditions. Also provided herein are medicaments or pharmaceutical compositions comprising one or more 14-membered macrolide derivatives together with one or more pharmaceutically acceptable carriers, excipients, diluents or mixture thereof, and methods for treating or preventing acne vulgaris and associated inflammatory conditions.Type: ApplicationFiled: November 22, 2006Publication date: March 19, 2009Inventors: Dilip J. Upadhyay, Anjan Chakrabarti, Biswajit Das, Radhakrishnan Gowrishankar
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Publication number: 20090048147Abstract: The present invention relates to a compound comprising a peptide moiety, a linker moiety and a water-soluble polymer moiety such as a poly(ethylene glycol) moiety. The linker moiety is between the peptide moiety and the water-soluble polymer moiety. In certain embodiments, the linker moiety has the structure: wherein ?, ?, and ? are each integers whose values are independently selected. In other embodiments the linker moiety has the following structure: wherein ?, ?, and ? are each integers whose values are independently selected. In other embodiments the linker moiety has the following structure: wherein ?, ?, ?, and ? are each integers whose values are independently selected. Alternatively, the linker structure may have the following structure: wherein ? and ? are each integers whose values are independently selected.Type: ApplicationFiled: January 30, 2008Publication date: February 19, 2009Applicant: Affymax, Inc.Inventors: Christopher P. Holmes, Anjan Chakrabarti, Brian T. Frederick, Yijun Pan, Yaohua S. Dong, Ashok Bhandari
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Publication number: 20090018174Abstract: Provided herein are macrolide derivatives that can be useful in treating or preventing inflammatory diseases. Also provided are pharmaceutical compositions comprising one or more macrolide derivatives optionally together with one or more pharmaceutically acceptable carriers, excipients, diluents or mixtures thereof, as well as methods for treating or preventing inflammatory diseases.Type: ApplicationFiled: November 8, 2006Publication date: January 15, 2009Inventors: Pradip Kumar Bhatnagar, Anjan Chakrabarti, Biswajit Das, Malini Bajpai, Abhijit Ray
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Publication number: 20090005292Abstract: The present invention relates to peptide compounds that are agonists of the erythropoietin receptor (EPO-R). The invention further relates to therapeutic methods using such peptide compounds to treat disorders associated with insufficient or defective red blood cell production. Pharmaceutical compositions, which comprise the peptide compounds of the invention, are also provided.Type: ApplicationFiled: November 11, 2005Publication date: January 1, 2009Applicant: AFFYMAX, INC.Inventors: Christopher P. Holmes, Qun Yin, Genet Zemede, Ashok Bhandari, David Tumelty, Guy Lalonde, Palani Balu, Peter J. Schatz, William J. Dower, Anjan Chakrabarti, Yaohua S. Dong, Brian T. Frederick, Nicholas C. Wrighton
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Publication number: 20090005325Abstract: Provided herein are ketolide derivatives, which can be used as antibacterial agents. Compounds described herein can be used for treating or preventing conditions caused by or contributed to by gram positive, gram negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Bacillus, Enterobactericeae, Propionibacterium acnes or any combination thereof. Also provided are processes for preparation of compounds described herein, pharmaceutical compositions thereof, and methods of treating bacterial infections.Type: ApplicationFiled: November 21, 2006Publication date: January 1, 2009Inventors: Biswajit Bas, Anjan Chakrabarti, Ramadass Venkataramanan, Atul Kashinath Hajare, Anish Bandyopadhyay, Rita Katoch, Gobind Singh Kapkoti, Yogash Baban Surase, Mohammad Salman, Dilip J. Upadhyay
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Publication number: 20080287376Abstract: The present invention provides ketolide derivatives, which can be used as antibacterial agents. In particular, compounds described herein can be used for treating or preventing conditions caused by or contributed to by Gram-positive, Gram-negative or anaerobic bacteria, more particularly against, for example, Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp. Chlamydia spp., Mycoplasm, Legionella spp., Mycobacterium, Helicobacter, Clostridium, Bacteroides, Corynebaclerium, Bacillus or Enterobactericeae. Also provided are processes for preparing such ketolide derivatives, pharmaceutical compositions thereof, and methods of treating bacterial infections.Type: ApplicationFiled: July 28, 2005Publication date: November 20, 2008Applicants: RANBAXY LABORATORIES LIMITEDInventors: Biswajit Das, Mohammad Salman, Atul Kashinath Hajare, Ramadass Venkataramanan, Rita Katoch, Rajesh Kumar, Gobind Singh Kapkoti, Anjan Chakrabarti, Anish Bandyopadhyay, Santosh Haribhau Kurhade, Yogesh Baban Surase, Ashok Rattan
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Publication number: 20080207536Abstract: The present invention provides acylide derivatives, which can be used as antibacterial agents. Compounds disclosed herein can be used for the treatment or prevention of a condition caused by or contributed to by Gram-positive, Gram-negative or anaerobic bacteria, more particularly against bacterium such as Staphylococci, Streptococci, Enterococci, Haemophilus, Moraxalla spp., Chlamydia spp., Mycoplasm, Legionella spp., Myobacterium, Helicobacter, Clostridium, Bacteroides, Corynebacterium, Baccillus or Enterobactericeae. Processes for the preparation of disclosed compounds, pharmaceutical compositions thereof, and method of treating bacterial infections, are also provided.Type: ApplicationFiled: July 13, 2005Publication date: August 28, 2008Applicant: RANBAXY LABORATORIES LIMITEDInventors: Biswajit Das, Rita Katoch, Atul Kashinath Hajare, Gobind Singh Kapkoti, Anish Bandyopadhyay, Ramadass Venkataramanan, Rajesh Kumar, Santosh Haribhau Kurhade, Sujata Rathy, Anjan Chakrabarti, Yogesh Baban Surase, Mohammad Salman, Ashok Rattan