Abstract: There is disclosed in one example a computer apparatus, including: a hardware platform including a central processor unit (CPU) and a memory; and instructions encoded within the memory to instruct the CPU to: enumerate a plurality of running processes, and associate resource demands with the running processes; predict a resource starvation condition for at least one process; rank the plurality of running processes according to a dynamic ranking algorithm, wherein the ranking algorithm includes user engagement as an input for ranking a process; and according to the ranking and a safeguard algorithm, deallocate resources from a process ranked lower than the at least one process and assign the deallocated resources to the at least one process to mitigate the predicted resource starvation condition.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Abstract: A technique for collecting and using signal reputation data, comprising obtaining a plurality of signal reputation data corresponding to a plurality of locations, categorizing the signal reputation data into groups, calculating signal circles for at least some of the groups based on a representative signal value for the corresponding group, calculating a signal reputation score for each signal circle, determining a best signal circle for a user mobile device within a predetermined distance of dead zones, and sending the best signal circle to the user mobile device based at least in part on the signal reputation score and a location of the user mobile device. In some embodiments, the technique may include some but not all of these actions and additional actions, such as suspending obtaining signal reputation data based on battery status.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGF?) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: There is disclosed in one example a computer apparatus, including: a hardware platform including a central processor unit (CPU) and a memory; and instructions encoded within the memory to instruct the CPU to: enumerate a plurality of running processes, and associate resource demands with the running processes; predict a resource starvation condition for at least one process; rank the plurality of running processes according to a dynamic ranking algorithm, wherein the ranking algorithm includes user engagement as an input for ranking a process; and according to the ranking and a safeguard algorithm, deallocate resources from a process ranked lower than the at least one process and assign the deallocated resources to the at least one process to mitigate the predicted resource starvation condition.

Abstract: A technique for collecting and using signal reputation data, comprising obtaining a plurality of signal reputation data corresponding to a plurality of locations, categorizing the signal reputation data into groups, calculating signal circles for at least some of the groups based on a representative signal value for the corresponding group, calculating a signal reputation score for each signal circle, determining a best signal circle for a user mobile device within a predetermined distance of dead zones, and sending the best signal circle to the user mobile device based at least in part on the signal reputation score and a location of the user mobile device. In some embodiments, the technique may include some but not all of these actions and additional actions, such as suspending obtaining signal reputation data based on battery status.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Abstract: This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGF?) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors contanining substituted 2-pyridones and therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: A technique for collecting and using signal reputation data, comprising obtaining a plurality of signal reputation data corresponding to a plurality of locations, categorizing the signal reputation data into groups, calculating signal circles for at least some of the groups based on a representative signal value for the corresponding group, calculating a signal reputation score for each signal circle, determining a best signal circle for a user mobile device within a predetermined distance of dead zones, and sending the best signal circle to the user mobile device based at least in part on the signal reputation score and a location of the user mobile device. In some embodiments, the technique may include some but not all of these actions and additional actions, such as suspending obtaining signal reputation data based on battery status.

Abstract: The present application discloses compounds that are inhibitors of Btk, compounds that are inhibitors of PI3K?, and compounds that are dual inhibitors of both Btk and PI3K?. Also described are methods for synthesizing such inhibitors and methods for using such inhibitors for the treatment of diseases wherein inhibition of Btk and PI3K? provides a therapeutic benefit to a patient having the disease.

Abstract: This disclosure provides compounds and compositions and methods of using those compounds and compositions to treat diseases and disorders associated with excessive transforming growth factor-beta (TGF?) activity. This disclosure also provides methods of using the compounds in combination with one or more cancer immunotherapies.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Abstract: Novel bromodomain and extraterminal domain (BET) inhibitors and to therapeutic methods of treating conditions and diseases using these novel BET inhibitors are provided.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.

Abstract: The disclosure relates to anti-cancer compounds derived from nuclear steroid receptor binders, to products containing the same, as well as to methods of their use and preparation.