Abstract: The invention includes a method including the steps of obtaining a plurality of images, each of the images in the plurality having at least one corresponding region, generating a merged image, the merged image also having the corresponding region. The step of generating includes selecting an image source from the plurality of images to source image data for the corresponding region in the merged image by comparing attributes of the corresponding regions of the plurality of images to identify the image source having preferred attributes.

Abstract: The invention belongs to the technical field of biomedical testing, and particularly relates to a biomarker for diagnosis, treatment, and prognosis for hepatocellular carcinoma bone metastasis (HCC) and application thereof. The application of biomarker VAPA for preparing a reagent or a kit for diagnosis, treatment, and prognosis for HCC bone metastasis. The application of the reagent that detects VAPA expression levels in blood and tissues for preparing a reagent or kit for diagnosis, treatment, and prognosis for HCC bone metastasis. Compared with the diagnostic kits in the prior art that can only detect bone metastasis after it has occurred, the VAPA described in this invention offers a more specific and sensitive assay kit for the early prediction, diagnosis, disease progression assessment, treatment efficacy evaluation, drug guidance, and prognosis assessment of HCC bone metastasis. Additionally, the VAPA may also serve as a target for therapeutic interventions in bone metastasis.

Abstract: A pyridopyrimidinone derivative as represented by formula I, and a tautomer, a stereoisomer, a hydrate, a solvate, a pharmaceutically acceptable salt thereof or a prodrug thereof. The pyridopyrimidinone derivative has a good SOS1 inhibitory effect.

Abstract: The present disclosure generally relates to a pre-tightening disc spring, comprising a disc-shaped body which is integrally formed, the disc-shaped body being formed with a central hole, the disc-shaped body having a first contact side and a second contact side which are opposite to each other in a thickness direction of the disc-shaped body, the disc-shaped body being a rotation solid formed by rotating a radial section about a central rotation axis by 360 degrees, the central rotation axis coinciding with a central axis of the central hole, the radial section having a first line segment and an opposing second line segment, the first contact side being defined by rotating the first line segment, the second contact side being defined by rotating the second line segment, a medium-diameter axis being defined to passing a mid-point of the second line segment and extending normally relative to the second line segment, the radial section being mirror-symmetrical relative to the medium-diameter axis, the medium-dia

Abstract: In implementations of systems for estimating temporal occurrence of a binary state change, a computing device implements an occurrence system to compute a posterior probability distribution for temporal occurrences of binary state changes associated with client computing devices included in a group of client computing devices. The occurrence system determines probabilities of a binary state change associated with a client computing device included in the group of client computing devices based on the posterior probability distribution, and the probabilities correspond to future periods of time. A future period of time is identified based on a probability of the binary state change associated with the client computing device. The occurrence system generates a communication based on a communications protocol for transmission to the client computing device via a network at a period of time that correspond to the future period of time.

Abstract: A high-formability hot galvanized aluminum-zinc or hot galvanized aluminum-magnesium dual-phase steel having a tensile strength of ?590 MPa and a rapid heat treatment hot dipping fabrication method, the steel comprising the following components in mass percentage: C: 0.045-0.12%; Si: 0.1-0.5%; Mn: 1.0-2.0%; P: ?0.02%; S: ?0.006%; and Al: 0.02-0.055%. The steel may also contain one or two among Cr, Mo, Ti, Nb, and V, wherein the Cr+Mo+Ti+Nb+V?0.5%, and the remainder is Fe and other inevitable impurities. The present invention changes the recovery of a deformed structure, ferrite recrystallization and austenite transformation processes during annealing by means of rapid heat treatment, and the nucleation point of a crystal is increased, grain growth time is shortened, the strength and formability (n90 value) of the material is improved while heat treatment efficiency is improved, which thus extends the performance range of the material.

Abstract: A low-carbon and low-alloy dual-phase steel and hot-dip galvanized dual-phase steel having tensile strength greater than or equal to 980 MPa and a method for manufacturing by means of rapid heat treatment. The steel has the following chemical components in percentage by mass: C: 0.05-0.17%, Si: 0.1-0.7%, Mn: 1.4-2.8%, P?0.020%, S?0.005%, B?0.005%, and Al: 0.02-0.055%, and may further contain two or more of Nb, Ti, Cr, Mo, and V, Cr+Mo+Ti+Nb+V?1.1%, the balance is Fe and other inevitable impurities. The method for manufacturing the steel comprises: smelting, casting, hot rolling, cold rolling and rapid heat treatment procedures. According to the present invention, the recovery, recrystallization and austenite transformation process of a deformed structure is changed, the nucleation rate is increased, the grain growth time is shortened, grains are refined, the strength of the material is improved, and the performance range of the material is expanded.

Abstract: The present invention relates to novel phosphorous (V) (P(V)) reagents methods for preparing thereof, and methods for preparing nucleoside phosphorothioate compounds by using the novel reagents.

Abstract: Disclosed is a communication method for a device, a first cloud platform and a second cloud platform. The communication method includes obtaining, by the first cloud platform, a first access token from the second cloud platform. The first access token is configured for the first cloud platform to access a second resource link of a second device on the second cloud platform, and the second device is connected to the second cloud platform. The method also includes obtaining, by the first cloud platform, the second resource link based on the first access token. The method further includes determining, by the first cloud platform, a first resource link of the second device on the first cloud platform based on the second resource link. The first resource link is configured for a first device connected to the first cloud platform to communicate with the second device.

Abstract: In the automatic welding method and device for prestressed tubular piles provided in the present application, which is applied in welding equipment, a detection is conducted around a connection position between prestressed tubular piles and a position of a target welding seam is obtained. Then the target welding seam is welded around the prestressed tubular piles according to the position of the target welding seam.

Abstract: The embodiments of the present disclosure may provide an oncolytic virus vector and an application thereof. The oncolytic virus vector may comprise a recombinant nucleic acid. The recombinant nucleic acid may include: (i) a first nucleic acid fragment encoding a soluble PD-1 molecule; (ii) a second nucleic acid fragment encoding a CD86 molecule; and (iii) a third nucleic acid fragment encoding an antibody to a CD3 molecule.

Abstract: The present invention relates to the field of coal mine underground auxiliary transportation equipment, and particularly relates to an overhead monorail driving unit group realizing mechanical fast power distribution. The overhead monorail driving unit group realizing mechanical fast power distribution includes a rail, wherein the rail is connected with driving portions, carrying trolleys and a hoisting beam, the hoisting beam is disposed in a middle position of the driving portions and the carrying trolleys, and the driving portions, the carrying trolleys and the hoisting beam are connected through driving portion short pull rods, frame-shaped pull rods and driving portion long pull rods.

Abstract: A light-emitting substrate includes: a substrate; and at least one coupling portion and at least one auxiliary cathode pattern disposed on the substrate. Each auxiliary cathode region is provided with a coupling portion and an auxiliary cathode pattern coupled to the coupling portion. The auxiliary cathode pattern includes at least one disconnection portion, and each disconnection portion includes first, second and third conductive pattern layers. An orthographic projection of an edge of the second conductive pattern layer on the substrate is located within orthographic projections of edges of the third and first conductive pattern layers on the substrate. A total perimeter of at least one orthographic projection, on the substrate, of at least one edge of at least one third conductive pattern layer in the at least one disconnection portion is greater than a perimeter of an orthographic projection of an edge of the auxiliary cathode region on the substrate.

Abstract: There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-? related diseases, such as Alzheimer's disease.

Abstract: A method of assaying an analyte in a sample is disclosed. The method includes having a sample holder with a sample contact area for contacting a sample with an analyte, having a plurality of calibration structures on the sample contact area of the sample holder, imaging a part of the sample contact area that has the calibration structures, and using an algorithm that includes an image, calibration structures in the image, and artificial intelligence and/or machine learning to identify the analyte and/or determine the analyte concentration.

Abstract: The present disclosure relates to the technical field of agricultural microorganisms and crop cultivation and more specifically relates to a compound mycorrhizal fungus growth promoting agent and an agricultural-photovoltaic complementary planting method for Dioscorea composita. The compound mycorrhizal fungus growth promoting agent for Dioscorea composita includes Glomus mosseae, Streptomyces chartreusis and plant growth promoting rhizobacteria, and can greatly improve photosynthesis of Dioscorea composita under a photovoltaic panel and promote growth and development of Dioscorea composita. The compound mycorrhizal fungus growth promoting agent is used, an unoccupied land under a solar photovoltaic panel is utilized, and a high-ridge close planting method is used to combine a solar photovoltaic industry and Dioscorea composita planting. The whole planting process is easy to operate, the cost is low, and three-dimensional value-added utilization of land is achieved.

Abstract: Disclosed is a software PUF based on an RISC-V processor for IoT security. A 32-bit RISC-V processor is used to generate abnormal information results in an abnormal operating state under a low voltage, and the abnormal information results are used to represent the features of the 32-bit RISC-V processor; 5-bit binary data obtained by comparing the abnormal information results with normal information results has high randomness and uniqueness and it is extremely difficult to directly extract internal abnormal information result from a hardware circuit of the 32-bit RISC-V processor, so modeling attacks based on the 5-bit binary data calculated according to the abnormal information results of the 32-bit RISC-V processor are almost impossible; in addition, when the 32-bit RISC-V processor is in an abnormal operating state, the operating frequency of the 32-bit RISC-V processor is dynamically adjusted through a frequency compensation method.

Abstract: Disclosed are an optical anti-counterfeiting element and an optical anti-counterfeiting product utilizing the same, the optical anti-counterfeiting element comprising: a substrate (12) including a first surface and a second surface opposite to each other; micro-sampling tools (11) on the first surface; and one or more micro graphic and text units formed on the second surface, wherein the micro graphic and text unit includes micro graphic and text strokes, the micro graphic and text strokes are arranged in a non-periodic and non-fixed-geometry manner, and when the second surface is observed through the micro-sampling tools, a stereoscopic animated anti-counterfeiting feature can be seen.

Abstract: Systems and methods dynamically adjust an available range for editing an attribute in an image. An image editing system computes a metric for an attribute in an input image as a function of a latent space representation of the input image and a filtering vector for editing the input image. The image editing system compares the metric to a threshold. If the metric exceeds the threshold, then the image editing system selects a first range for editing the attribute in the input image. If the metric does not exceed the threshold, a second range is selected. The image editing system causes display of a user interface for editing the input image comprising an interface element for editing the attribute within the selected range.

Abstract: An optical module includes an optical receiver with a complementary metal-oxide semiconductor (CMOS) transimpedance amplifier (TIA) and a digital signal processing (DSP) circuit. The DSP circuit is integrated with the CMOS TIA and facilitates adaptability of the CMOS TIA, and the CMOS TIA can adapt by using information provided by the DSP circuit.