Patents by Inventor Anke Dienelt

Anke Dienelt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for enrichment of cells
    Patent number: 10758573
    Abstract: The present invention is directed to a device for enriching cells with a cell surface marker, comprising an aptamer suitable for specifically binding the cell surface marker, and beads coupled thereto, wherein the aptamer is coupled to the beads in a manner that allows for release of cells expressing the cell surface marker, in the absence of a chemical agent, and production of a cell population enriched for cells expressing the cell surface marker, substantially free of beads and aptamer. Kits comprising the device or components thereof, and methods of cell enrichment, are also provided. In exemplary embodiments, the device contains an aptamer that specifically binds CD31.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: September 1, 2020
    Assignees: President and Fellows of Harvard College, CHARITÉUNIVERSITÄTSMEDIZIN BERLIN
    Inventors: Pascal Joly, Georg N. Duda, Thomas Schaus, Anke Dienelt, Andrea Sass, David J. Mooney
  • IMMUNMODULATION FOR PREVENTION OF POOR HEALING OF MUSCULOSKELETAL INJURIES IN COMPROMISED PATIENTS
    Publication number: 20200197341
    Abstract: The present invention relates to a compound for use in a method for treating a musculoskeletal injury, wherein the compound is a regulator of the pro-inflammatory response and particularly being capable of upregulating regulatory T cells and/or M2-macrophages; and/or being capable of downregulating the biological activity of effector CD8+ cells, and further comprising the dosage regimen administering an initial dose of said compound to a patient not before 24 hours after said musculoskeletal injury.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 25, 2020
    Applicant: CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN
    Inventors: Katharina SCHMIDT-BLEEK, Hans-Dieter VOLK, Sebastian WENDLER, Georg N. DUDA, Simon REINKE, Sven GEISSLER, Taimoor Hasan QAZI, Anke DIENELT, Hanna SCHELL
  • COMPOSITIONS AND METHODS FOR ENRICHMENT OF CELLS
    Publication number: 20180185417
    Abstract: The present invention is directed to a device for enriching cells with a cell surface marker, comprising an aptamer suitable for specifically binding the cell surface marker, and beads coupled thereto, wherein the aptamer is coupled to the beads in a manner that allows for release of cells expressing the cell surface marker, in the absence of a chemical agent, and production of a cell population enriched for cells expressing the cell surface marker, substantially free of beads and aptamer. Kits comprising the device or components thereof, and methods of cell enrichment, are also provided. In exemplary embodiments, the device contains an aptamer that specifically binds CD31.
    Type: Application
    Filed: June 9, 2016
    Publication date: July 5, 2018
    Inventors: Pascal Joly, Georg N. Duda, Thomas Schaus, Anke Dienelt, Andrea Sass, David J. Mooney