Patents by Inventor Anke Unger

Anke Unger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS
    Publication number: 20240415819
    Abstract: The present invention relates to certain macrocyclic compounds of the formula (I) and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment or prevention of a disease associated with and/or caused by proteasome or immunoproteasome, selected from a cancer, an infectious disease, an inflammatory disease, and autoimmune disease.
    Type: Application
    Filed: September 25, 2022
    Publication date: December 19, 2024
    Inventors: Uwe Koch, Gunther Zischinsky, Anke Unger, Peter Nussbaumer, Bert Klebl, Axel Choidas, Klaus Dinkel, Julian Engel, Carsten Degenhart, Robert Huber, Kiyean Nam, Jaesung Kim, Jeongjea Seo, Seung-Joo Lee, Yeejin Jeon, Wongyun Ahn
  • COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION
    Publication number: 20240252454
    Abstract: The present invention relates to a composition comprising at least one inhibitor of mitochondrial transcription (IMT) and at least one anti-cancer drug. Furthermore, the present invention is directed to compositions for use as a medicament and to compositions for use in the treatment and/or prevention of cancer.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 1, 2024
    Inventors: Tim BERGBREDE, Raffaella DI LUCREZIA, Anke UNGER, Axel CHOIDAS, Bert KLEBL, Peter NUSSBAUMER, Sascha MENNINGER, Peter HABENBERGER, Gunther ZISCHINSKY, Uwe KOCH, Peter SCHRÖDER, Pavla JESTRABOVÁ, Lenka PALOVÁ-JELÍNKOVÁ, Klára DÁNOVÁ, Maria FALKENBERG-GUSTAFSSON, Laleh ARABANIAN, Claes GUSTAFSSON, Nils-Göran LARSSON, Lars PALMQVIST
  • Coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer
    Patent number: 11111238
    Abstract: The invention provides novel coumarin derivatives as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: September 7, 2021
    Assignees: Lead Discovery Center GmbH, Max Planck Gesellschaft zur Förderung der Wissenschften e.V., SOTIO a.s.
    Inventors: Raffaella Di Lucrezia, Tim Bergbrede, Peter Nussbaumer, Uwe Koch, Bert Klebl, Axel Choidas, Anke Unger, Nils-Göran Larsson, Maria Falkenberg-Gustafsson, Claes M. Gustafsson
  • COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER
    Publication number: 20200291011
    Abstract: The invention provides novel coumarin derivatives as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.
    Type: Application
    Filed: September 20, 2018
    Publication date: September 17, 2020
    Inventors: Raffaella Di Lucrezia, Tim Bergbrede, Peter Nussbaumer, Uwe Koch, Bert Klebl, Axel Choidas, Anke Unger, Nils-Göran Larsson, Maria Falkenberg-Gustafsson, Claes M. Gustafsson
  • 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof for the treatment of cancer
    Patent number: 10703735
    Abstract: The invention provides novel 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: July 7, 2020
    Assignees: Lead Discovery Center GmbH, Max Planck Gesellschaft zur Förderung der Wissenschaften e. V.
    Inventors: Raffaella Di Lucrezia, Tim Bergbrede, Peter Nussbaumer, Uwe Koch, Bert Klebl, Axel Choidas, Anke Unger, Nils-Göran Larsson, Maria Falkenberg-Gustafsson, Claes M. Gustafsson
  • 4-PHENYL-COUMARIN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND USES THEREOF FOR THE TREATMENT OF CANCER
    Publication number: 20200031794
    Abstract: The invention provides novel 4-phenyl-coumarin derivatives, processes for their preparation and uses thereof as specific mitochondrial RNA polymerase inhibitors for the treatment of cancer.
    Type: Application
    Filed: July 23, 2019
    Publication date: January 30, 2020
    Inventors: Raffaella Di Lucrezia, Tim Bergbrede, Peter Nussbaumer, Uwe Koch, Bert Klebl, Axel Choidas, Anke Unger, Nils-Göran Larsson, Maria Falkenberg-Gustafsson, Claes M. Gustafsson