Abstract: The invention relates to a transmucosal patch comprising electrospun fibers comprising a biocompatible polymer and a therapeutically effective amount of a pharmaceutical active ingredient, wherein the active pharmaceutical ingredient comprises a cannabinoid or an opioid or a cannabinoid and an opioid, and its use as a medicament.

Abstract: A method is provided for an in vitro detection of a first protein in a sample, including the steps of: a) separating the sample by a native separation method; b) transferring the separated sample onto a membrane; c) contacting the membrane with an aptamer which specifically binds to the first protein; and d) detecting the first protein by detecting the aptamer bound to the first protein.

Abstract: An application device applies an active agent to a fibrous material. The application device has a housing defining a storage volume which is arranged in the housing and is intended for storing the active agent, and an applicator. By the applicator, the active agent located in an application volume is applied to the material. In order to make reliable and straightforward application possible, the applicator has an application volume, a number of hollow teeth which are arranged in a comb-like manner and have an upper wall and a lower wall, between which at least part of the application volume is arranged, and also gaps which are located between the teeth and are intended for introducing the material into the application volume.

Abstract: The present invention describes a method for an in vitro detection of a first protein in a sample, comprising the steps of: a) separating the sample by means of a native separation method; b) transferring the separated sample onto a membrane; c) contacting the membrane with an aptamer which specifically binds to the first protein; and d) detecting the first protein by detecting the aptamer bound to the first protein.

Abstract: The invention relates to a device for applying at least one application agent to hair, comprising a housing unit (11a; 11b; 11c) which at least partially encloses at least one depot volume (12a; 12b; 12c) for accommodating at least one component of the at least one application agent (10a; 10b; 10c). According to the invention, the device comprises a dispenser unit (13a; 13b; 13c) which is designed to discharge the at least one component of the application agent (10a; 10b; 10c) from an application agent container (14a; 14b; 14c) that is at least partially inserted into the depot volume (12a; 12b; 12c).

Abstract: An application device applies an active agent to a fibrous material. The application device has a housing defining a storage volume which is arranged in the housing and is intended for storing the active agent, and an applicator. By the applicator, the active agent located in an application volume is applied to the material. In order to make reliable and straightforward application possible, the applicator has an application volume, a number of hollow teeth which are arranged in a comb-like manner and have an upper wall and a lower wall, between which at least part of the application volume is arranged, and also gaps which are located between the teeth and are intended for introducing the material into the application volume.

Abstract: The invention relates to a device for applying at least one application agent to hair, comprising a housing unit (11a; 11b; 11c) which at least partially encloses at least one depot volume (12a; 12b; 12c) for accommodating at least one component of the at least one application agent (10a; 10b; 10c). According to the invention, the device comprises a dispenser unit (13a; 13b; 13c) which is designed to discharge the at least one component of the application agent (10a; 10b; 10c) from an application agent container (14a; 14b; 14c) that is at least partially inserted into the depot volume (12a; 12b; 12c).

Abstract: The invention starts out from an applicator for applying at least one application medium (10a; 10b; 10c, 52c) to hair, with a separation unit (11a; 11Ib; 11c), which forms at least two application gaps (12a, 13a, 14a, 15a, 16a; 13b; 12c, 13c, 14c, 15c, 16c) that are provided for receiving some of the hairs for application of the application medium (10a; 10b; 10c, 52c). It is proposed that at least one of the application gaps (12a, 13a, 14a, 15a, 16a; 13b; 12c, 13c, 14c, 15c, 16c) has an opening width that is smaller, at least by a factor of 10, than a distance between the application gaps (12a, 13a, 14a, 15a, 16a; 13b; 12c, 13c, 14c, 15c, 16c).

Abstract: The invention relates to an applicator device for applying at least one application agent (10a) to fibrous material, in particular an applicator device for applying an application agent (10a) to hair. Said device comprises a housing unit (11a) that contains at least one depot volume (12a) for storing the application agent(s) (10a) and at least one application volume (13a) that is connected to the depot volume (12a).