Abstract: Contrast agent destruction transmissions have reduced biological effect in medical diagnostic ultrasound. Ramping-up amplitude and/or ramping-down frequency reduce biological effect. The amplitude ramps up linearly or non-linearly. The change in amplitude or frequency occurs over a single waveform or over a sequence of separate transmissions. An envelope of the single waveform or the sequence of separate transmissions has a non-uniform, asymmetrical, symmetrical, rectangular or other shape. For example, the frequency ramp-down is provided with a non-Gaussian envelope. The amplitude ramp-up or frequency ramp-down is a progressively increasing destructive characteristic or ability, destroying contrast agent at different regions relative to focal regions with a minimum of acoustic energy.

Abstract: Methods and systems for varying a pattern as a function of steering angle for medical imaging with a multidimensional array are provided. Transmit waveform, delay, phase or apodization patterns in addition to delays, phases or apodization for focusing are used with a multidimensional array. By applying a periodic variation perpendicular to the steering direction, the effects of grating lobes due to the variation may be reduced. Along the steering direction, additional offsets are not provided, but may be provided. This different or non-existent offsets provide less grating lobe clutter. The transmit aperture is adjusted to be parallel to a direction of steering of non-normal transmit scan line or scan lines. The variation pattern is selected to result in enhancement or isolation of one or more frequency bands from one or more other frequency bands, such as isolation of second harmonic information from fundamental transmit frequency information.

Abstract: Multiple receive beams are formed for each transmission for rapid acquisition. The receive aperture is shifted as a function of the position of each receive beam. Multiple receive beams with differently positioned apertures are formed in response to a single transmit beam. Alternatively or additionally, the apodization varies as a function of the position of the receive beam relative to the transmit beam. Multiple receive beams with different apodization profiles are formed in response to a single transmission. The apodization and/or aperture variations in different receive beams may reduce geometric distortion and/or clutter levels for receiving multiple beams in response to a single transmission.

Abstract: Control of the sonothrombolysis treatment is automated based on feedback from ultrasound. The region to be treated may be tracked to provide ongoing treatment at the desired location. The treatment may be triggered based on detection of sufficient perfusion. The number or intensity of destructive ultrasound pulses may adapt to the number of remaining contrast agents. The treatment may be ceased or modified based on the efficacy.

Abstract: The therapeutic ultrasound waveform is used as a source of stress or ARFI pushing pulse. When the therapeutic ultrasound waveform ceases, diagnostic ultrasound is used to measure the strain, such as measuring tissue displacement. The displacement over time after release of the stress indicates tissue characteristics. The tissue characteristics may be monitored to determine when sufficient therapeutic results are obtained.

Abstract: Contrast agents may more effectively clear a clot if they are as close to the clot as possible. Radiation force may effectively push and/or pull the contrast agents next to the clot and away from the middle of any flow channels. By transmitting driving acoustic energy, the contrast agents may be positioned for treatment that is more effective by destruction.

Abstract: Destructive or therapy events are indicated in medical ultrasound imaging. Audible, visual, vibratory or other feedback is provided to the user. The feedback indicates the use of the destructive or therapy events. A characteristic of the indicator may provide further information, such as the power level or other operating condition.

Abstract: Transducer with different array configurations and methods of using the transducers are provided. An electrode layer on one side of a transducer device defines a one-dimensional array of elements. An electrode layer on an opposite side of the transducer device defines a multi-dimensional array. For example, one transducer device may be used for both two-dimensional imaging and three-dimensional imaging in response to the one-dimensional array and multi-dimensional array electrode configurations. Real time three-dimensional imaging and two-dimensional imaging may be provided with a single transducer. As another example, elements defined by one electrode configuration have a different surface area than elements defined by another electrode configuration. The different configurations on opposite sides of the transducer devices may be a same type (e.g. both one-dimensional arrays) or different types.

Abstract: An image formed from compounded frames of ultrasound data acquired with different steering angles is displayed. Each component frame is associated with a scan of the entire displayed region. A majority of scan lines for each component frame are pointed in one direction or the same relative direction, and a minority of the scan lines are steered at different angles within each component frame to scan the rest of the display region, but with a different steering angle for the majority of scan lines of each of the component frames. As a result, the benefits of spatial compounding component frames associated with different steering angles are provided without having to apply filtering to reduce line artifacts.

Abstract: An image formed from compounded frames of ultrasound data acquired with different steering angles is displayed. Each component frame is associated with a scan of the entire displayed region. A majority of scan lines for each component frame are pointed in one direction or the same relative direction, and a minority of the scan lines are steered at different angles within each component frame to scan the rest of the display region, but with a different steering angle for the majority of scan lines of each of the component frames. As a result, the benefits of spatial compounding component frames associated with different steering angles are provided without having to apply filtering to reduce line artifacts.

Abstract: Transducer with different array configurations and methods of using the transducers are provided. An electrode layer on one side of a transducer device defines a one-dimensional array of elements. An electrode layer on an opposite side of the transducer device defines a multi-dimensional array. For example, one transducer device may be used for both two-dimensional imaging and three-dimensional imaging in response to the one-dimensional array and multi-dimensional array electrode configurations. Real time three-dimensional imaging and two-dimensional imaging may be provided with a single transducer. As another example, elements defined by one electrode configuration have a different surface area than elements defined by another electrode configuration. The different configurations on opposite sides of the transducer devices may be a same type (e.g. both one-dimensional arrays) or different types.

Abstract: A medical ultrasonic imaging system uses an adaptive multi-dimensional back-end mapping stage to eliminate loss of information in the back-end, minimize any back-end quantization noise, reduce or eliminate electronic noise, and map the local average of soft tissue to a target display value throughout the image. The system uses spatial variance to identify regions of the image corresponding substantially to soft tissue and a noise frame acquired with the transmitters turned off to determine the mean system noise level. The system then uses the mean noise level and the identified regions of soft tissue to both locally and adaptively set various back-end mapping stages, including the gain and dynamic range.

Abstract: Speckle is reduced by compounding data associated with different aperture positions. The data is responsive to transmission and reception along the same scan lines. The data is detected and then combined.

Abstract: Medical diagnostic ultrasound methods and systems for automated flow analysis are provided. Multiple cross-sectional areas along a vessel are determined automatically. A processor locates an abnormality as a function of the multiple cross-sectional areas, such as identifying a cross-sectional area that is a threshold amount less than an average cross-sectional area. The abnormal area is highlighted on the display to assist with medical diagnosis. For the carotid artery, the interior and exterior branches are labeled to assist medical diagnosis. The two branches are automatically identified. The branch associated with additional small branches is identified as the exterior carotid.

Abstract: A medical ultrasonic imaging system uses an adaptive multi-dimensional back-end mapping stage to eliminate loss of information in the back-end, minimize any back-end quantization noise, reduce or eliminate electronic noise, and map the local average of soft tissue to a target display value throughout the image. The system uses spatial variance to identify regions of the image corresponding substantially to soft tissue and a noise frame acquired with the transmitters turned off to determine the mean system noise level. The system then uses the mean noise level and the identified regions of soft tissue to both locally and adaptively set various back-end mapping stages, including the gain and dynamic range.