Abstract: Computing devices, wearable devices, networked environments, and methods for bio-signal acquisition and monitoring skeletomuscular parameters are provided. First data indicative of movement parameters of knee joint of a patient for a test type is obtained from a wearable device. Second data indicative patient-specific parameters of the patient are obtained. A cluster to which the patient belongs is identified based on the patient-specific parameters and a prediction model. A normative range for the test type for the cluster is determined. The first data is processed to determine whether the patient falls within the normative range of the cluster and result is provided.