Patents by Inventor Ann Aulabaugh

Ann Aulabaugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescence polarization assays for binding of caspase inhibitors and probes therefor
    Publication number: 20070065898
    Abstract: This invention provides a fluorescence polarization assay useful in the detection and evaluation of caspases inhibitors. This invention also provides novel fluorescent probes used in the fluorescence polarization assay, and methods for making the fluorescent probes, which have the Formula I: wherein the constituent variables are as defined herein.
    Type: Application
    Filed: September 21, 2006
    Publication date: March 22, 2007
    Applicant: Wyeth
    Inventors: Paul Dollings, Gregory Tawa, Ann Aulabaugh
  • 5-Substituted-3(2H)-furanones useful for inhibition of farnesyl-protein transferase
    Patent number: 6710078
    Abstract: Compounds of Formula (I): wherein R1, R2, R3, X, Y, Z and Q are as defined in the specification which compounds are inhibitors of Ras farnesyl-protein transferase enzyme (FPTase), and useful in treating ras oncogene-dependent tumors, such as cancers of the pancreas, colon, bladder, and thyroid and processes for the preparation of said compounds of Formula (I).
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: March 23, 2004
    Assignee: Wyeth Holdings Corporation
    Inventors: Semiramis Ayral-Kaloustian, Irwin Hollander, Ann Aulabaugh
  • 5-Substituted-3(2H)-furanones useful for inhibition of farnesyl-protein transferase
    Publication number: 20030073736
    Abstract: Compounds of Formula (I): 1
    Type: Application
    Filed: August 23, 2002
    Publication date: April 17, 2003
    Applicant: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Irwin Hollander, Ann Aulabaugh