Patents by Inventor Ann Begovich

Ann Begovich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190226026
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 2, 2018
    Publication date: July 25, 2019
    Inventors: Yonghong LI, Steven SCHRODI, Ann BEGOVICH, Monica CHANG, Michele CARGILL
  • Patent number: 10301679
    Abstract: The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: May 28, 2019
    Assignee: Celera Corporation
    Inventors: Steven J. Schrodi, Ann Begovich
  • Patent number: 10253349
    Abstract: Provided herein are methods and compositions for detecting gene fusions, e.g., relevant to cancer. The present methods and compositions can be used to detect gene fusions with very high sensitivity and specificity. The present methods and compositions can detect gene fusions, e.g., in free circulating tumor RNA from a plasma sample.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: April 9, 2019
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Ann Begovich, Rajiv Dua, Dwight Kuo, Xiaoju Max Ma, Ellen Ordinario
  • Publication number: 20190024174
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: May 29, 2018
    Publication date: January 24, 2019
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • Publication number: 20180346994
    Abstract: Provided herein are methods and compositions for multiplex detection of a large number of actionable gene fusions with very high sensitivity and specificity. The present methods and compositions can detect ALK, RET, and ROS1 gene fusions, optionally in combination with other mutations and fusions.
    Type: Application
    Filed: May 30, 2018
    Publication date: December 6, 2018
    Inventors: Ann Begovich, Cindy Cheung, Javelin Chi, Grantland Hillman, Dwight Kuo, Michael Lee, Chitra Manohar, Xiaoju Max Ma, Ellen Ordinario, Jaya Rajamani, Huan Truong
  • Patent number: 10131949
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: November 20, 2018
    Assignee: Celera Corporation
    Inventors: Yonghong Li, Steven Schrodi, Ann Begovich, Monica Chang
  • Patent number: 10006088
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: June 26, 2018
    Assignee: Celera Corporation
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • Publication number: 20170145503
    Abstract: The present invention provides compositions and methods based on genetic polymorphisms that are associated with autoimmune disease, particularly rheumatoid arthritis. For example, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by these nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and variant proteins, and methods of using the nucleic acid molecules and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: October 4, 2016
    Publication date: May 25, 2017
    Applicant: CELERA CORPORATION
    Inventors: Steven J. Schrodi, Ann Begovich
  • Publication number: 20170022564
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: May 11, 2016
    Publication date: January 26, 2017
    Inventors: Ann BEGOVICH, Ellen BEASLEY, Michele CARGILL, Steven SCHRODI
  • Publication number: 20160304937
    Abstract: Provided herein are methods and compositions for detecting gene fusions, e.g., relevant to cancer. The present methods and compositions can be used to detect gene fusions with very high sensitivity and specificity. The present methods and compositions can detect gene fusions, e.g., in free circulating tumor RNA from a plasma sample.
    Type: Application
    Filed: April 15, 2016
    Publication date: October 20, 2016
    Inventors: Ann Begovich, Rajiv Dua, Dwight Kuo, Xiaoju Max Ma, Ellen Ordinario
  • Publication number: 20160244836
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: December 9, 2015
    Publication date: August 25, 2016
    Inventors: Yonghong LI, Steven SCHRODI, Ann BEGOVICH, Monica CHANG, Michele CARGILL
  • Patent number: 9371565
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: June 21, 2016
    Assignee: Celera Corporation
    Inventors: Ann Begovich, Ellen Beasley, Michelle Cargill, Steven Schrodi
  • Publication number: 20150259744
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: January 26, 2015
    Publication date: September 17, 2015
    Inventors: Ann BEGOVICH, Ellen BEASLEY, Michelle CARGILL, Steven SCHRODI
  • Patent number: 8975022
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: December 12, 2012
    Date of Patent: March 10, 2015
    Assignee: Celera Corporation
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • Publication number: 20120082678
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: April 5, 2011
    Publication date: April 5, 2012
    Applicant: CELERA CORPORATION
    Inventors: Yonghong LI, Ann BEGOVICH, Monica CHANG, Michele CARGILL, Steven SCHRODI
  • Publication number: 20120010274
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: July 1, 2011
    Publication date: January 12, 2012
    Applicant: CELERA CORPORATION
    Inventors: Ann BEGOVICH, Ellen BEASLEY, Michele CARGILL, Steven SCHRODI
  • Patent number: 7993833
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: August 9, 2011
    Assignee: Celera Corporation
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi
  • Patent number: 7947451
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: May 24, 2011
    Assignee: Celera Corporation
    Inventors: Yonghong Li, Ann Begovich, Monica Chang, Michele Cargill, Steven Schrodi
  • Publication number: 20090162348
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: December 1, 2008
    Publication date: June 25, 2009
    Applicant: CELERA CORPORATION
    Inventors: Yonghong LI, Ann BEGOVICH, Monica CHANG, Michele CARGILL, Steven SCHRODI
  • Publication number: 20080108713
    Abstract: The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
    Type: Application
    Filed: August 31, 2007
    Publication date: May 8, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Ann Begovich, Ellen Beasley, Michele Cargill, Steven Schrodi