Patents by Inventor Ann Daugherty

Ann Daugherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Delivery of proteins across polar epithelial cell layers
    Patent number: 7824695
    Abstract: This invention provides bioactive conjugates. The bioactive conjugates include: (1) a cell recognition moiety that binds to ?2 macroglobulin receptor ?2-MR and (2) a bioactive moiety which: (a) has a biological activity, (b) does not function solely as an immunogen to invoke an immune response and (c) does not have ADP ribosylating activity. The bioactive conjugates of this invention are useful in methods of transporting the bioactive moiety across a polar epithelial membrane. Thus, this invention provides methods for parenteral administration of proteins without injection.
    Type: Grant
    Filed: October 18, 2000
    Date of Patent: November 2, 2010
    Assignees: The United States of America as represented by the Department of Health and Human Services, Genentech, Inc.
    Inventors: David J. FitzGerald, Randall J. Mrsny, Marian McKee, Ann Daugherty
  • Compaction assay for assessment of respiratory disease therapy
    Publication number: 20050164334
    Abstract: A compaction assay measuring the viscoelasticity of sputum samples of patients subject to respiratory disease is provided. This assay is useful in determining the therapeutic efficacy of DNase, antibiotic and other respiratory disease treatments in improving lung function.
    Type: Application
    Filed: January 10, 2005
    Publication date: July 28, 2005
    Applicant: Genentech, Inc.
    Inventors: Ann Daugherty, Randy Mrsny, Thomas Patapoff