Patents by Inventor Ann Killary

Ann Killary has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7169384
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Grant
    Filed: June 15, 2005
    Date of Patent: January 30, 2007
    Assignee: Board of Regents, The University of Texas System
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Publication number: 20060019281
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Application
    Filed: June 15, 2005
    Publication date: January 26, 2006
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Patent number: 6943245
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: September 13, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Ann Killary, Steve Lott, Dawn Chandler
  • Patent number: 6818401
    Abstract: The present invention relates to a method for detection and interpretation of loss-of-function or gain-of-function mutations for test genes of interest. The genes of interest include those associated with inherited genetic disorders. The present invention involves the process of obtaining a sample of genetic material from an individual in the form of tissue or cells, separation of the genetic material from the cells of the individuals into haploid sets by transferring the individual chromosomal entities into a population of target cells, and monitoring the target cell population for successful transfer and expression of the test genes of interest using various functional, immunological and structural assays.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: November 16, 2004
    Assignees: Board of Regents University of Texas System, Baylor College of Medicine
    Inventors: Arthur Beaudet, Olaf Bodamer, Ann Killary, Maria Mercedes Lovell
  • Publication number: 20020137067
    Abstract: The present invention relates to a method for detection and interpretation of loss-of-function or gain-of-function mutations for test genes of interest. The genes of interest include those associated with inherited genetic disorders. The present invention involves the process of obtaining a sample of genetic material from an individual in the form of tissue or cells, separation of the genetic material from the cells of the individuals into haploid sets by transferring the individual chromosomal entities into a population of target cells, and monitoring the target cell population for successful transfer and expression of the test genes of interest using various functional, immunological and structural assays.
    Type: Application
    Filed: October 2, 2001
    Publication date: September 26, 2002
    Inventors: Arthur Beaudet, Olaf Bodamer, Ann Killary, Maria Mercedes Lovell
  • Publication number: 20020119541
    Abstract: The present invention relates to a new tumor suppressor, designated CAR-1, the gene for which is located on the short arm of human chromosome 1. This gene is directly implicated in colon, kidney and breast cancers, and the CAR-1 ubiquitous expression of the corresponding transcript suggests that it may be involved in yet others. Thus, one aspect of the invention is the diagnosis of CAR-1-related malignancies. The full length cDNA for CAR-1, as well as oligonucleotides derived therefrom, are disclosed. Screening methods for modulators of CAR-1 function and expression, as well as methods for cancer therapy, are described.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 29, 2002
    Inventors: Ann Killary, Steve Lott, Dawn Chandler