Patents by Inventor Ann-Kristin Müller

Ann-Kristin Müller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Malaria vaccines based on pre-erythrocytic antigens from
    Patent number: 10548960
    Abstract: The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the polypeptides of the invention. It further relates to compositions comprising such polypeptides or fragments thereof or the nucleic acid molecules, in particular combinations of such polypeptides or fragments thereof, and the use of such compositions as malaria vaccines.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: February 4, 2020
    Assignee: RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG
    Inventors: Johannes Pfeil, Kirsten Heiss, Ann-Kristin Müller
  • Malaria Vaccines Based on Pre-Erythrocytic Antigens From P. Falciparum
    Publication number: 20170072039
    Abstract: The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the polypeptides of the invention. It further relates to compositions comprising such polypeptides or fragments thereof or the nucleic acid molecules, in particular combinations of such polypeptides or fragments thereof, and the use of such compositions as malaria vaccines.
    Type: Application
    Filed: September 23, 2016
    Publication date: March 16, 2017
    Inventors: Johannes PFEIL, Kirsten HEISS, Ann-Kristin MÜLLER
  • Malaria vaccines based on apicomplexan ferlins, ferlin-like proteins and other C2-domain containing proteins
    Patent number: 8968750
    Abstract: The present invention relates to peptides comprising at least one antigenic determinant or epitope of an apicomplexan Ferlin, Ferlin-like protein and/or another C2-domain containing protein for use as malaria vaccines. It further relates to compositions comprising said peptides and to the use of such compositions as malaria vaccines.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: March 3, 2015
    Assignee: Ruprecht-Karls-Universität Heidelberg
    Inventors: Ann-Kristin Mueller, Eva Morath
  • MALARIA VACCINES BASED ON PRE-ERYTHROCYTIC ANTIGENS FROM P. FALCIPARUM
    Publication number: 20130323276
    Abstract: The present invention relates to polypeptides or fragments thereof for use as malaria vaccines. It also relates to nucleic acid molecules coding for the polypeptides of the invention. It further relates to compositions comprising such polypeptides or fragments thereof or the nucleic acid molecules, in particular combinations of such polypeptides or fragments thereof, and the use of such compositions as malaria vaccines.
    Type: Application
    Filed: December 6, 2011
    Publication date: December 5, 2013
    Applicant: RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG
    Inventors: Johannes Pfeil, Kirsten Heiss, Ann-Kristin Müller
  • MALARIA VACCINES BASED ON APICOMPLEXAN FERLINS, FERLIN-LIKE PROTEINS AND OTHER C2-DOMAIN CONTAINING PROTEINS
    Publication number: 20120308598
    Abstract: The present invention relates to peptides comprising at least one antigenic determinant or epitope of an apicomplexan Ferlin, Ferlin-like protein and/or another C2-domain containing protein for use as malaria vaccines. It further relates to compositions comprising said peptides and to the use of such compositions as malaria vaccines.
    Type: Application
    Filed: December 6, 2010
    Publication date: December 6, 2012
    Inventors: Ann-Kristin Mueller, Eva Morath
  • Live genetically attenuated malaria vaccine
    Patent number: 8168166
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: May 1, 2012
    Assignees: Seattle Biomedical Research Institute, Walter and Eliza Hall Institute of Medical Research
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • LIVE GENETICALLY ATTENUATED MALARIA VACCINE
    Publication number: 20110033502
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: May 6, 2008
    Publication date: February 10, 2011
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • Live genetically engineered protozoan vaccine
    Patent number: 7722860
    Abstract: The invention provides methods for inducing an immune response in a vertebrate host against a protozoan parasite, comprising administering to the host a live protozoan parasite that is genetically engineered to disrupt a stage-specific gene function that is required by the protozoan parasite to establish a secondary infection in the vertebrate host. Representative protozoan parasites belong to the phyla Apicomplexa and Kinetoplastida. The vertebrate host may be a mammal or a bird.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: May 25, 2010
    Assignee: Seattle Biomedical Research Institute
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7718165
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: December 20, 2004
    Date of Patent: May 18, 2010
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live Genetically Attenuated Malaria Vaccine
    Publication number: 20080032388
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: December 20, 2004
    Publication date: February 7, 2008
    Applicants: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7261884
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: August 28, 2007
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Publication number: 20070009556
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: August 30, 2006
    Publication date: January 11, 2007
    Applicants: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan Kappe, Kai-Uwe Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Patent number: 7122179
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a gene whose expression is up-regulated in liver stage parasites and whose function is not required for entry into hose hepatocytes.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: October 17, 2006
    Assignees: Seattle Biomedical Research Institute, Ruprecht-Karls-Universität Heidelberg
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller
  • Live genetically attenuated malaria vaccine
    Publication number: 20050226896
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: March 11, 2005
    Publication date: October 13, 2005
    Applicants: Seattle Biomedical Research Institute, Ruprecht-Karls-Universitat Heidelberg
    Inventors: Stefan Kappe, Kai-Uwe Matuschewski, Ann-Kristin Mueller