Abstract: The present disclosure is directed to methods for treating Crohn's disease, and in particular, to methods for inducing clinical remission and/or endoscopic improvement of Crohn's disease, using a JAK1 inhibitor. In certain embodiments, the patient is administered an induction dose of the JAK1 inhibitor to induce clinical remission and/or endoscopic improvement of the Crohn's disease, followed by administration of at least one maintenance dose of the JAK1 inhibitor thereafter. In other embodiments, the present disclosure is directed to methods for treating ulcerative colitis using a JAK1 inhibitor.

Abstract: A system, apparatus and method of integrating a wireless telephone in a vehicle are provided. The system, apparatus and method consist of installing a parabolic speaker in the vehicle that has a focused listening area at a location where an operator of the vehicle may he situated. The parabolic speaker may further have an integrated microphone. When a wireless telephone is placed in a cradle, that may be available in the vehicle for receiving the telephone, the telephone will be integrated in the vehicle. Consequently, the telephone will interact with the vehicle's on-board computer (OBC). The OBC may then route all in-coming signals from the wireless telephone to the parabolic speaker. Further, the OBC may route all out-going signals from the integrated microphone to the wireless telephone.

Abstract: In transferring a user application from an original user environment to a new user environment by dragging and dropping a graphical image representative of the user application, a new object or "shadow part" is automatically created in the new user environment with the same attributes as the user application in the original user environment. The new object also inherits the characteristics of other objects in the new user environment. The new object may optionally be linked to the original user application so that setting changes in one user environment are reflected in the other.