Patents by Inventor Ann Pitruzzello

Ann Pitruzzello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9339195
    Abstract: An apparatus, system, and method are disclosed for detecting seizure symptoms in an individual 102. A sensor module 202 receives physiological data for an individual 102 from one or more sensors 110, 112, such as a heart activity sensor. A feature detection module 204 detects a predefined feature 500, 520, 530, 540 in the physiological data. The predefined feature 500, 520, 530, 540 is associated with a seizure or another medical condition. An alert module 206 broadcasts an alert in response to the feature detection module 204 detecting the predefined feature 500, 520, 530, 540.
    Type: Grant
    Filed: January 27, 2011
    Date of Patent: May 17, 2016
    Assignee: RESEARCH TRIANGLE INSTITUTE
    Inventors: Ann Pitruzzello, Barbara Kroner, Jamie Shorey, David C Strube
  • Publication number: 20140308688
    Abstract: A multiple flow-based microfluidic cell culture system that emulates mammalian physiology is provided. Tissue-mimicking cell cultures are connected by flow within a physiologically meaningful arrangement so that the pharmacokinetics of various agents to be tested in the system emulate in vivo conditions. The system includes at least two organ tissue modules, each organ tissue module including a first chamber containing an organ tissue cell, the first chamber including an inlet and an outlet for flow of an organ tissue cell-specific culture medium; a second chamber including an inlet and an outlet for flow of a blood material; and a semi-permeable membrane separating the first and second chambers. The flow of blood material through each organ tissue module is interconnected and the flow of tissue-cell specific culture medium is directed to a single organ tissue module.
    Type: Application
    Filed: December 7, 2012
    Publication date: October 16, 2014
    Inventors: Sonia Grego, Brian Rhys Stoner, Kristin Hedgepath Gilchrist, Timothy Raymond Fennell, Ann Pitruzzello
  • Publication number: 20130116514
    Abstract: An apparatus, system, and method are disclosed for detecting seizure symptoms in an individual 102. A sensor module 202 receives physiological data for an individual 102 from one or more sensors 110, 112, such as a heart activity sensor. A feature detection module 204 detects a predefined feature 500, 520, 530, 540 in the physiological data. The predefined feature 500, 520, 530, 540 is associated with a seizure or another medical condition. An alert module 206 broadcasts an alert in response to the feature detection module 204 detecting the predefined feature 500, 520, 530, 540.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 9, 2013
    Applicant: Research Triangle Institute
    Inventors: Barbara Kroner, Ann Pitruzzello, Jamie Shorey, David C. Strube