Patents by Inventor Ann R. Kelly

Ann R. Kelly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for highly enantio- and diastereoselective synthesis of acyclic epoxy alcohols and allylic epoxy alcohols
    Patent number: 8236976
    Abstract: The inventive subject matter relates to novel processes for making an epoxy alcohol from an aldehyde, comprising the steps of: (a) adding (i) an organozinc compound or (ii) divinylzinc compound and an diorganozinc compound to said aldehyde in the presence of a first catalyst to form an allylic alkoxide compound; and (b) epoxidizing said allylic alkoxide compound in the presence of an oxidant and a second catalyst.
    Type: Grant
    Filed: March 9, 2005
    Date of Patent: August 7, 2012
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Patrick Walsh, Alice E. Lurain, Ann R. Kelly, Aaron G. Maestri
  • INTRAMOLECULAR AZIDE-ALKYNE CYCLOADDITION
    Publication number: 20100280238
    Abstract: The Huisgen 1,3-dipolar cycloaddition is a ‘click’ reaction that results from the ligation of azides and alkynes to give a triazole moiety. This reaction has been shown to be effective in the formation of a variety of macrocyclic rings. A key point of interest is the regioselectivity and specificity of the cycloaddition. Disclosed herein are specific, selective, and high-yielding methods of azide-alkyne macrocyclization to form 1,4- and 1,5-triazoles and libraries thereof.
    Type: Application
    Filed: April 29, 2010
    Publication date: November 4, 2010
    Inventors: Lisa A. Marcaurelle, Ann R. Kelly, Sarathy Kesavan, Jingqiang Wei, Damian W. Young
  • Processes for Highly Enantio- and Diastereoselective Synthesis of Acyclic Epoxy Alcohols and Allylic Epoxy Alcohols
    Publication number: 20090163728
    Abstract: The inventive subject matter relates to novel processes for making an epoxy alcohol from an aldehyde, comprising the steps of: (a) adding (i) an organozinc compound or (ii) divinylzinc compound and an diorganozinc compound to said aldehyde in the presence of a first catalyst to form an allylic alkoxide compound; and (b) epoxidizing said allylic alkoxide compound in the presence of an oxidant and a second catalyst.
    Type: Application
    Filed: March 9, 2005
    Publication date: June 25, 2009
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Patrick Walsh, Alice E. Lurain, Ann R. Kelly, Aaron G. Maestri