Abstract: Provided is a new means for suppressing inflammation or suppressing inflammatory cytokine production. Provided is a device in which a weak pulse current is passed through a living body or living tissue to suppress inflammation in the living body or the living tissue. This device is provided with a power supply means, and a current control means for receiving a supply of power to intermittently apply a direct current at prescribed intervals, and is configured such that the current control means includes a pulse width modulation control means, and the pulse width modulation control means generates a pulse wave that is a rectangular wave, and in which the time indicating a peak value for rising in one cycle of the pulse wave (“pulse duration”) is at least 0.1 millisecond, the peak value is 1.0-20 V, inclusive, and the duty ratio of the pulse wave is at least 5.5%.

Abstract: An exemplary apparatus and method are provided for suppressing an inflammation or an inflammatory cytokine production. For example, the exemplary apparatus and method can cause a weak pulse current to be passed through a living body or living tissue to suppress the inflammation in the living body or the living tissue. The exemplary apparatus can include a power supply device, and a current control device for receiving a supply of power to intermittently apply a direct current at prescribed intervals. The current control device can include a pulse width modulation control device, and the pulse width modulation control device can generate a pulse wave that is a rectangular wave. A time indicating a peak value for rising in one cycle of the pulse wave (“pulse duration”) can be at least 0.1 millisecond, the peak value can be in the range of 1.0V to 20 V, inclusive, and the duty ratio of the pulse wave can be at least 5.5%.