Patents by Inventor Ann Stapleton

Ann Stapleton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions for treating Escherichia coli urinary tract infections
    Patent number: 6432681
    Abstract: Compositions and methods for diagnosing, treating and preventing recurrent E.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: August 13, 2002
    Assignees: The Regents of the University of Washington, The Biomembrane Institute
    Inventors: Ann Stapleton, Edward Nudelman, Walter E. Stamm, Sen-Itiroh Hakomori
  • Method for determining susceptibility to Escherichia coli urinary tract infections, method for diagnosing secretors and nonsecretors, and method and medicament for preventing Escherichia coli urinary tract infections
    Patent number: 6130205
    Abstract: A method for determining susceptibility to E. coli urinary tract infection comprising assaying a sample of epithelial cells for the presence or absence of at least one of Le.sup.a, sialosyl galactosyl-globoside, disialosyl galactosyl-globoside and an extended globo structure carrying the same terminal epitopes as Le.sup.a, sialosyl galactosyl-globoside or disialosyl galactosyl-globoside or assaying a sample of vaginal secretions for the presence or absence of at least one of sialosyl galactosyl-globoside or disialosyl galactosyl-globoside, and detecting the presence or absence of the at least one of Le.sup.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 10, 2000
    Assignees: The Regents of the University of Washington, The Biomembrane Institute
    Inventors: Ann Stapleton, Edward Nudelman, Sen-itiroh Hakomori, Walter E. Stamm, Mark Stroud
  • Method for determining susceptibility to escherichia coli urinary tract infections and method for diagnosing secretors and nonsecretors
    Patent number: 5374532
    Abstract: A method for determining susceptibility to E. coli urinary tract infection comprising assaying a sample of epithelial cells for the presence or absence of at least one of sialosyl galactosyl-globoside, disialosyl galactosyl-globoside and an extended globo structure carrying the same terminal epitopes as sialosyl galactosyl-globoside or disialosyl galactosyl-globoside, or assaying a sample of vaginal secretions for the presence or absence of at least one of sialosyl galactosyl-globoside or disialosyl galactosyl-globoside, and detecting the presence or absence of the at least one of sialosyl galactosyl-globoside, disialosyl galactosyl-globoside and the extended globo structure, a medicament comprising a biologically effective amount of at least one E. coli bacterial receptor analogue and a pharmaceutically acceptable diluent, carrier or excipient as well as a method for preventing E. coli urinary tract infection comprising administering to a host a biologically effective amount of at least one E.
    Type: Grant
    Filed: August 31, 1992
    Date of Patent: December 20, 1994
    Assignee: The Biomembrane Institute
    Inventors: Ann Stapleton, Edward Nudelman, Sen-itiroh Hakomori, Walter E. Stamm