Abstract: Portable charge capture/inventory management systems and methods include a system comprising at least one server at a first location. The server of an embodiment includes inventory data and patient data. The inventory data includes information of drugs and supplies of a facility that is a patient treatment facility. The patient data includes identification, schedule and treatment data of patients of the facility. The system includes at least one portable client at the facility that is coupled to the server. The portable client is configured to access and present the patient data for use during treatment of each patient, and to capture transaction data of the treatment at a point of care. The transaction data is automatically transferred to the server.