Abstract: This invention relates to the detection and diagnosis of tuberculosis. More specifically, the invention relates to new biomarkers and combinations thereof that enable the accurate detection and diagnosis of tuberculosis.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: This invention relates to the detection and diagnosis of tuberculosis. More specifically, the invention relates to new biomarkers and combinations thereof that enable the accurate detection and diagnosis of tuberculosis.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: A system is provided for employing an orchestrator to deploy and implement changes to a system. A change request may be a system build, upgrade, and patches for updating a subset of files within the system. The orchestrator may initially perform a security check and a validation check on a received change request. Upon receiving validation and approval, the change request may be deployed and propagated through a series of deployment scopes. The deployment scopes may become increasingly larger to extensively test the applied change before fully implementing the change on the target system. The orchestrator may submit the applied change to a validation component for getting validation of the change within the deployment scope after each applied change within a deployment scope. After the change request has been deployed through the deployment scopes and validated, the change request may be deployed to the target system and fully implemented.

Abstract: There is provided an antigenic composition comprising (a) a first mycobacterial antigenic polypeptide or a first mycobacterial polynucleotide; and (b) a second mycobacterial antigenic polypeptide or a second mycobacterial polynucleotide; wherein: (i) said first mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 1 or 7, or a fragment thereof having at least 7 consecutive amino acids thereof; (ii) said first mycobacterial polynucleotide comprises a polynucleotide sequence encoding said first mycobacterial antigenic polypeptide; (iii) said second mycobacterial antigenic polypeptide comprises a polypeptide sequence having at least 70% amino acid sequence identity to the amino acid sequence of SEQ ID NO: 5, or a fragment thereof having at least 7 consecutive amino acids thereof; and (iv) said second mycobacterial polynucleotide comprises a polynucleotide sequence encoding said second mycobacterial polypeptid

Abstract: A short-nosed wheeled walking aid has (a) a substantially horizontal base member having a front perimeter, a rear perimeter, a right perimeter and a left perimeter; (b) a front wheel assembly mounted to and supporting the base member adjacent the front perimeter, (c) a rear wheel assembly mounted to and supporting the base member adjacent the rear perimeter, (d) at least three upright right panels mounted on the base member, (e) a hand grip spaced behind and substantially parallel to the upright rear panel having a ground height (height off the ground, measured from the plane on which the wheels rest) of from about thirty to about forty inches, and (f) a seat assembly mounted to the exterior side of the rear panel, the seat assembly including a seat member translatable from a substantially vertical posture substantially parallel to the rear panel to a substantially horizontal posture substantially normal to the rear panel. A method of assisting the ambulation of a person employs the wheeled walking aid.

Abstract: A package coating is processed by applying a plurality of aqueous mixtures over a substrate. The aqueous mixtures each include a combination of pigments and binders. A packaging article is also disclosed that is made from the package coating on a substrate. Additionally, a packaging system is included that contains commercial product.

Abstract: A package coating is processed by applying a plurality of aqueous mixtures over a substrate. The aqueous mixtures each include a combination of pigments and binders. A packaging article is also disclosed that is made from the package coating on a substrate. Additionally, a packaging system is included that contains commercial product.

Abstract: A baby support assembly 10 which includes selectively stackable members 12, 30 which cooperatively and selectively support the positioning of a baby 91 upon the lap 92 of a mother or other individual 90.

Abstract: A novel tile and tub scraper is disclosed comprising two flat blade holders adapted to fit in the palm of the hand and having a scraper blade secured between the blade holders. One blade holder has a horizontal groove thereon for gripably receiving a forefinger where the other blade holder has an indentation substantially vertical to the groove for gripably receiving a thumb, the edge of the scraper blade substantially horizontal to said groove.