Abstract: The present application relates to an antibody, kit, detection method, and sample analyzer for detecting thyroid stimulating hormone. Specifically, the present application relates to a monoclonal antibody or antigen-binding antibody fragment thereof that specifically binds to thyroid stimulating hormone (TSH), wherein the antibody can recognize TSH variant R55G and does not cross-react with an ?-subunit shared by human luteinizing hormone (LH), follicle stimulating hormone (FSH), human chorionic gonadotropin (hCG), and free glycoprotein hormones, and is particularly suitable for developing TSH detection kit with a functional sensitivity of ?0.0015 ?IU/ml. The present application also relates to a thyroid stimulating hormone detection kit, detection method, and sample analyzer.

Abstract: A system, method, and computer readable storage device are provided for providing a dynamic tachometer. Based on various signal inputs from a plurality of data sources, a tachometer may be dynamically modified to include visual information and assistance to the driver in relation to the vehicle's engine speed (i.e., revolution speed of the vehicle's crankshaft). The tachometer may include one or a combination of: dynamic shift point indicators, a target engine speed range indicator, an overspeed indicator, and a power take-off mode indicator.

Abstract: The present disclosure provides genetically modified host cells that produce a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative. The present disclosure provides methods of synthesizing a cannabinoid, a cannabinoid derivative, a cannabinoid precursor, or a cannabinoid precursor derivative.

Abstract: Information-security LoRa-wave sensing is used to protect ATMs with LoRa modulator with spread-spectrum modulation techniques and/or transparent laser-guided systems 3D image generation to scan/monitor ATM card slots and ATM keypads for skimmers, fake keypads, etc. Sensor(s) with a DCNN/StNet-based algorithm are trained on 3D dimensions for card slot and keypad. Normal vs. detected constant weight of the keypad as well as weight distribution when keys are depressed are detected. Normal vs. disrupted signals based on the foregoing are observed and used to detect unauthorized objects. NB-IoT LoRa-waves initiate an alarm process. Additional features, functionality, and details are disclosed.

Abstract: A microfluidic device is configured to sample, meter and collect a metered volume of body fluid for analysis by means of capillary transport. The device comprises: an inlet section, for receiving the body fluid sample, the inlet section comprising an inlet port; a metering section configured to receive body fluid from the inlet section and comprising a metering channel, wherein the metering section is arranged to separate a metered volume of body fluid filled in the metering channel; and an outlet section comprising a cavity between an outlet part of the metering channel and an outlet orifice of the device, a hydrophilic porous bridge element conformable to a shape of the cavity and inserted in the cavity to substantially fill the cavity and the outlet orifice, and a capillary means attached to the outlet section in contact with the hydrophilic porous bridge element.

Abstract: The invention relates to a hybrid tailgate for a vehicle, comprising a thermoplastic inner structure forming the carrier frame of the tailgate, and at least one composite reinforcement part to reinforce the carrier frame, wherein the composite reinforcement part is connected to the thermoplastic inner structure at a first surface, wherein the composite reinforcement part forms a continuous load path in the inner structure enclosing a tailgate window opening for a window glazing part of the tailgate. Furthermore, the invention relates to a vehicle comprising such a hybrid tailgate. Moreover, the invention relates to a method of manufacturing such a hybrid tailgate, the method comprising forming a composite laminate part into an insert; placing the insert in an injection molding tool; and over-molding the insert with polymer resin.

Abstract: In various embodiments, a hair treatment device is provided. The hair treatment device can have a device body, at least one sensor arranged in or on the device body for detecting a hair condition parameter, and an electronic circuit device arranged in or on the device body. The electronic circuit device can be coupled to the at least one sensor for receiving the detected hair condition parameter, and the electronic circuit device can be configured, based on the received detected hair condition parameter, to control at least one hair treatment parameter and/or to dose at least one hair treatment agent and/or to provide a hair treatment recommendation.

Abstract: Devices and methods are provided for identifying individual monomeric units in sequential order as they are released or cleaved from a polymer strand via an enzyme, which acts on the polymer, and the monomeric units translocate through a transmembrane channel. Methods are also provided for identifying molecules as they translocate through a transmembrane channel.

Abstract: The present invention relates to a liquid composition of live Mollicutes bacteria and a stabiliser, whereby the stabiliser is a natural deep-eutectic solvent (NADES). In this liquid composition the live Mollicutes are stabilised without need for freezing or freeze-drying. This allows various advantageous uses in diagnostics and medicine, specifically as a liquid vaccine for use against infection or disease caused by Mollicutes bacteria, for human- or non-human animals.

Abstract: The present disclosure is directed to methods of treating patients with chronic kidney disease (CKD), with and without Type 2 diabetes, with an SGLT2 inhibitor, such as dapagliflozin.

Abstract: Embodiments provided herein relate to systems for synthetically-engineered reciprocal chromosomal translocation for gene insertion into a population of organisms such as insects.

Abstract: An automatic feeder system may include: an input bin configured to store at least one physical request slip; a feeder unit; and a support frame. The feeder unit may include a feed neck operable to automatically obtain a physical request slip from the input bin and convey it out from an outlet of the feed neck. The support frame may support the feeder unit so that the outlet is configured to engage with an input of a retailer system engaged with the automatic feeder system such that conveyance of the physical request slip out from the outlet causes the physical request slip to enter the input of the retailer system and cause the retailer system to generate a physical ticket for the game of chance based on the physical request slip.

Abstract: This invention relates to a second generation, plant-produced synthetic Orbivirus candidate vaccine. The vaccine comprises a plant produced chimaeric Orbivirus virus like particle (VLP) comprising at least one structural protein from one Orbivirus serotype and at least one structural protein selected from another serotype of the Orbivirus, wherein both structural capsid proteins are from the same Orbivirus species. In particular the invention relates to a vaccine against an Orbivirus, a method of producing chimaeric Orbivirus virus-like particles (VLPs) for use in a method of prevention and/or treatment of an Orbivirus infection, the use of the chimaeric Orbivirus VLPs in the manufacture of a vaccine for an Orbivirus, and a method of preventing and/or treating an Orbivirus infection.

Abstract: A laundry appliance includes a cabinet defining a front opening in a front panel. The front opening is defined by a lip having a curved edge. The lip defines a plurality of apertures spaced-apart around the front opening. A tub is disposed within the cabinet. The tub defines an access opening aligned with the front opening. A drum is disposed within the tub. A bellows assembly extends between the cabinet and the tub. The bellows assembly includes a projection coupled to the curved edge of the cabinet. A deflector has a rim and a chute wherein the chute extends toward the drum. The rim is configured to snap-fit over the projection of the bellows assembly. The rim includes a plurality of hooks where each hook is configured to extend through an aperture and interlock with the cabinet.

Abstract: Techniques are disclosed for session-based load-balancing of network traffic to network service instances. In one example, a network device receives a first packet of a forward packet flow from a network service instance of a plurality of network service instances after application of a network service. The first packet specifies a Media Access Control (MAC) address of the network service instance as a source MAC address. The network device defines a session comprising the forward packet flow and a reverse packet flow and stores an association between the session and the MAC address of the network service instance. The network device determines that a second packet received from a destination device is associated with the reverse packet flow of the session. The network device forwards the second packet to the same network service instance based on the association between the session and the MAC address of the network service instance.

Abstract: A system for magnetic resonance imaging of water exchange processes includes a primary magnet to provide a magnetic field over an imaging volume, a magnetic gradient coil to generate a spatial encoding in the magnetic field, a radiofrequency (RF) coil, and a data processor. The RF coil acquires, from the imaging volume, at multiple time points, water magnetic resonance signals including a first subset of signals labeled for a water exchange process and a second subset of signals that are not labeled. The data processor is configured to generate labeled images from the first subset of signals, generate control images corresponding to the set of labeled images from the second subset of signals, and calculate one or more parameters to characterize a water exchange process in the imaging volume between a first water compartment and a second water compartment based on the labeled images and the corresponding control images.

Abstract: A food product is provided. The food product may comprise a sugar blend; fat content consisting of less than 2% of solids in the food product by weight; and protein content consisting of less than 8% of solids in the food product by weight. The sugar blend may comprise at least 50% of solids in the food product by weight. The sugar blend may comprise galactose, glucose, and fructose in their respective monosaccharide forms or contained within disaccharides. Glucose, galactose, and fructose, respectively, may each constitute at least 1% of the sugar blend by weight. The food product may be formed as, for example, a gummy/chew, a sports gel, a drink mix, or a hydrated beverage. Methods of manufacture are additionally provided.

Abstract: Systems and methods are provided to provide guidance to a user regarding management of a physiologic condition such as diabetes. The determination may be based upon a patient glucose concentration level. The glucose concentration level may be provided to a stored model to determine a state. The guidance may be determined based at least in part on the determined state.

Abstract: Described herein is a probe for monitoring specific RNA splicing events, with utility for identifying molecular modulators of RNA splicing. The probe includes a nucleic acid, a first fluorescent element attached to a first end of the nucleic acid, and a second fluorescent element attached to a second end of the nucleic acid. The fluorescence signal of the probe changes when the probe hybridizes with either a pre-splicing RNA molecule or a splicing product. Also described herein is a method of monitoring RNA splicing and a method of screening of modulators of RNA splicing using the probe.

Abstract: The subject of the invention is a method of obtaining an antimicrobially active nonwoven fabric, which is prepared in an aqueous solution containing: • from 0.1 to 30 wt % citric acid, • from 0.1 to 20 wt % chitosan, • from 0.1 to 15 wt % zinc oxide, • from 0.01 to 3 wt % lawsone, and • and preferably natural essential oils in an amount of 0.01 to 5 wt %, especially of mint or lavender. In the next step, the prepared solution is applied to the non-woven fabric, which is then dried.