Patents by Inventor Anna De Fazio

Anna De Fazio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determinants of sensitivity to chemotherapeutic agents
    Patent number: 8673869
    Abstract: The present invention provides methods for determining the level of resistance of a tumor cell to one or more chemotherapeutic agents, comprising measuring the level of expression of a muscle ankyrin repeat protein in the tumor cell. The invention also provides methods for increasing the sensitivity of a tumor cell to one or more chemotherapeutic agents, comprising administering to the cell an effective amount of an antagonist of a muscle ankyrin repeat protein. The invention further provides compositions for use in accordance with methods of the invention.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: March 18, 2014
    Assignee: Western Sydney Local Health District
    Inventors: Anna De Fazio, Paul Robert Harnett, Alexander David Guminski
  • Determinants of Sensitivity to Chemotherapeutic Agents
    Publication number: 20090203133
    Abstract: The present invention provides methods for determining the level of resistance of a tumour cell to one or more chemotherapeutic agents, comprising measuring the level of expression of a muscle ankyrin repeat protein in the tumour cell. The invention also provides methods for increasing the sensitivity of a tumour cell to one or more chemotherapeutic agents, comprising administering to the cell an effective amount of an antagonist of a muscle ankyrin repeat protein. The invention further provides compositions for use in accordance with methods of the invention.
    Type: Application
    Filed: December 14, 2005
    Publication date: August 13, 2009
    Inventors: Anna De Fazio, Paul Robert Harnett, Alexander David Guminski