Patents by Inventor Anna Junker

Anna Junker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSTICS FOR DETECTING ECTO-5'-NUCLEOTIDASE (CD73)
    Publication number: 20250382322
    Abstract: The present invention relates to radio- and fluorescence-labeled compounds, as well as their use as Diagnostics for Detecting Ecto-5?-Nucleotidase (CD73). The invention is further directed to a pharmaceutical composition comprising said compounds as well as to the compounds and the pharmaceutical composition for use in a method of diagnosis of a disease associated with increased or decreased CD73-expression as well as in the treatment of a disease associated with increased CD73-expression.
    Type: Application
    Filed: February 17, 2023
    Publication date: December 18, 2025
    Applicant: EBERHARD KARLS UNIVERSITÄT TÜBINGEN
    Inventors: Anna JUNKER, DOBELMANN Clemens, HERMANN Sven, Sonja SCHELHAAS, Stefan WAGNER, Georg ROLSHOVEN, Constanze Cerine SCHMIES, Laura SCHÄKEL, Riham IDRIS, Katharina SYLVESTER, Haneen AL-HROUB, Christa E. MÜLLER, Eugen POTAPTSCHUK
  • PURINE AND PYRIMIDINE NUCLEOTIDES AS ECTO-5'-NUCLEOTIDASE INHIBITORS
    Publication number: 20210169911
    Abstract: Disclosed is a compound of formula (I), wherein Q, U, T, A, a, b, c, and n are as defined herein. Also disclosed are methods of inhibiting ecto-5?-nucleotidase, inhibiting suppression of an antitumor immune response, inhibiting tumor growth of a cancerous tumor, inhibiting metastasis of cancer in a mammal afflicted with cancer, synergistically enhancing a response of a mammal afflicted with cancer undergoing treatment with an immunotherapeutic anti-cancer agent, potentiating an activity of an inhibitor of nicotinamide phosphoribosyltransferase in a mammal undergoing treatment of a mammal with the inhibitor, and treating preeclampsia in a mammal in need thereof, comprising administering to an animal an effective amount of a compound of formula (I).
    Type: Application
    Filed: August 16, 2019
    Publication date: June 10, 2021
    Applicants: The United States of America,as represented by the Secretary,Department of Health and Human Services, University of Bonn, University of Münster
    Inventors: Kenneth A. Jacobson, Anna Junker, Mirko Scortichini, Clemens Dobelmann, Christian P. Renn, Vigneshwaran Namasivayam, Riham Mohammed Idris, Christa E. Müller
  • Triazole derivatives as P2Yreceptor antagonists
    Patent number: 10683277
    Abstract: Described are compounds, which are antagonists of the P2Y14 receptor, for example, a compound of formula (I) in which ring A, R1, R2, R3, and n are as described herein. Also provided are dendron conjugates comprising the compounds, and methods of using the compounds, including a method of treating a disorder, such as inflammation, diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, a condition associated with metabolic syndrome, and asthma, and a method of antagonizing P214 receptor activity in a cell.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: June 16, 2020
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Kenneth A. Jacobson, Anna Junker, Elisa Uliassi, Evgeny Kiselev
  • TRIAZOLE DERIVATIVESAS P2Y14 RECEPTOR ANTAGONISTS
    Publication number: 20180297981
    Abstract: Described are compounds, which are antagonists of the P2Y14 receptor, for example, a compound of formula (I) in which ring A, R1, R2, R3, and n are as described herein. Also provided are dendron conjugates comprising the compounds, and methods of using the compounds, including a method of treating a disorder, such as inflammation, diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, a condition associated with metabolic syndrome, and asthma, and a method of antagonizing P214 receptor activity in a cell.
    Type: Application
    Filed: September 23, 2016
    Publication date: October 18, 2018
    Applicant: The United States of America,as represented by the Secretary,Department of Health and Human Services
    Inventors: Kenneth A. Jacobson, Anna Junker, Elisa Uliassi, Evgeny Kiselev