Patents by Inventor Anna L. BLOIS

Anna L. BLOIS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the treatment of a cancer or fibrotic disorder associated with MENA or MENA(INV) by administering a map kinase inhibitor
    Patent number: 11242406
    Abstract: Phosphorylation and dephosphorylation of MENA and MENA isoforms regulates the metastatic activity of cancer cells. Administration of a MENA kinase inhibitor results in significant reduction in the development of cancer metastasis in established and developing tumors. Administration of a MENA kinase inhibitor in conjunction with a tyrosine kinase inhibitor enhances efficacy of tyrosine kinase inhibitor therapy. Administration of a MENA kinase inhibitor in conjunction with anti-microtubule agent results in significant reduction in chemotherapy-induced tumor cell dissemination and enhances efficacy of anti-microtubule therapy.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: February 8, 2022
    Assignee: METASTAT, INC.
    Inventors: Douglas A. Hamilton, Anna L. Blois
  • Methods and Compositions for Anticancer Therapies that Target MENA Protein Isoforms Kinases
    Publication number: 20190225707
    Abstract: Phosphorylation and dephosphorylation of MENA and MENA isoforms regulates the metastatic activity of cancer cells. Administration of a MENA kinase inhibitor results in significant reduction in the development of cancer metastasis in established and developing tumors. Administration of a MENA kinase inhibitor in conjunction with a tyrosine kinase inhibitor enhances efficacy of tyrosine kinase inhibitor therapy. Administration of a MENA kinase inhibitor in conjunction with anti-microtubule agent results in significant reduction in chemotherapy-induced tumor cell dissemination and enhances efficacy of anti-microtubule therapy.
    Type: Application
    Filed: July 7, 2017
    Publication date: July 25, 2019
    Inventors: Douglas A. HAMILTON, Anna L. BLOIS