Patents by Inventor Anna Laromaine Sagué

Anna Laromaine Sagué has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9829488
    Abstract: Three-dimensional cellular arrays, methods of making three-dimensional cellular arrays, and methods of identifying agents using the arrays are disclosed.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: November 28, 2017
    Assignee: President and Fellows of Havard College
    Inventors: Ratmir Derda, Anna Laromaine Sague, George M. Whitesides
  • Patent number: 9316210
    Abstract: An apparatus for generating useful energy includes a first chamber containing a draw solution which includes an osmotic agent and a second chamber containing a feed solution. A semi-permeable membrane allows the feed solution to move thereacross by osmosis, from the second chamber to the first chamber, to form a diluted draw solution. Pressurizing means apply a pressure to the diluted draw solution in the first chamber. Energy conversion means convert mechanical energy in the diluted draw solution, which is generated by osmotic movement of the feed solution across the semi-permeable membrane, into useful, electrical energy. The osmotic agent includes particles in the range of 0.5 nm-5 mm and the semi-permeable membrane has pores with diameters that are no larger than the diameter of the particles, thereby improving the amount of power or useful energy generated by the apparatus. There is further provided a corresponding method of generating power or useful energy.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: April 19, 2016
    Assignee: OSMOBLUE SARL
    Inventors: Elodie Dahan, Anna Laromaine Sagué
  • Patent number: 9090868
    Abstract: Alginate hydrogel fibers and related materials as well as methods for preparing such materials are provided. An alginate hydrogel fiber includes water in an amount of more than about 92% by weight of the fiber and a cross-linked alginate in an amount of about 0.1% to about 8% by weight of the fiber, wherein the cross-link is a cation. An alginate hydrogel paper includes one or more alginate hydrogel fibers, which form a non-woven matrix. Three-dimensional cellular arrays are also provided, wherein the alginate hydrogel making up the alginate paper is substantially index-matched with a predetermined culture medium. A method for making alginate hydrogel fiber and a method for index-matching alginate hydrogel paper with culture medium are provided. A kit for conducting biochemical, diagnostic, cellular, and/or non-cellular analysis comprises alginate hydrogel paper index-matched to culture medium.
    Type: Grant
    Filed: July 12, 2011
    Date of Patent: July 28, 2015
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Charles R. Mace, Jabulani Barber, Anna Laromaine Sagué, George M. Whitesides, Rebecca Cademartiri
  • Publication number: 20140349329
    Abstract: A device and methods for detecting the effect of compounds on an organism are provided. Furthermore, the device and methods disclosed herein allow for the fractionation of complex samples and the isolation of one or more organisms for the samples. The device and methods also allow for the study of development of the organism.
    Type: Application
    Filed: March 24, 2014
    Publication date: November 27, 2014
    Applicant: President and Fellows of Harvard College
    Inventors: George M. WHITESIDES, Anna LAROMAINE SAGUÉ, Ratmir DERDA, Charles R. MACE, Katherine A. MIRICA, Alfonso Reina CECCO, Suzanne HULME
  • Publication number: 20140197104
    Abstract: An apparatus for generating useful energy includes a first chamber containing a draw solution which includes an osmotic agent and a second chamber containing a feed solution. A semi-permeable membrane allows the feed solution to move thereacross by osmosis, from the second chamber to the first chamber, to form a diluted draw solution. Pressurizing means apply a pressure to the diluted draw solution in the first chamber. Energy conversion means convert mechanical energy in the diluted draw solution, which is generated by osmotic movement of the feed solution across the semi-permeable membrane, into useful, electrical energy. The osmotic agent includes particles in the range of 0.5 nm-5 mm and the semi-permeable membrane has pores with diameters that are no larger than the diameter of the particles, thereby improving the amount of power or useful energy generated by the apparatus. There is further provided a corresponding method of generating power or useful energy.
    Type: Application
    Filed: August 23, 2012
    Publication date: July 17, 2014
    Applicant: OSMOBLUE SARL
    Inventors: Elodie DAHAN, Anna LAROMAINE SAGUÉ
  • Publication number: 20130316387
    Abstract: Alginate hydrogel fibers and related materials as well as methods for preparing such materials are provided. An alginate hydrogel fiber includes water in an amount of more than about 92% by weight of the fiber and a cross-linked alginate in an amount of about 0.1% to about 8% by weight of the fiber, wherein the cross-link is a cation. An alginate hydrogel paper includes one or more alginate hydrogel fibers, which form a non-woven matrix. Three-dimensional cellular arrays are also provided, wherein the alginate hydrogel making up the alginate paper is substantially index-matched with a predetermined culture medium. A method for making alginate hydrogel fiber and a method for index-matching alginate hydrogel paper with culture medium are provided. A kit for conducting biochemical, diagnostic, cellular, and/or non-cellular analysis comprises alginate hydrogel paper index-matched to culture medium.
    Type: Application
    Filed: July 12, 2011
    Publication date: November 28, 2013
    Inventors: Charles R. Mace, Jabulani Barber, Anna Laromaine Sagué, George M. Whitesides, Rebecca Cademartiri
  • Publication number: 20110105360
    Abstract: Three-dimensional cellular arrays, methods of making three-dimensional cellular arrays, and methods of identifying agents using the arrays are disclosed.
    Type: Application
    Filed: March 27, 2009
    Publication date: May 5, 2011
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Ratmir Derda, Anna Laromaine Sague, George M. Whitesides