Patents by Inventor Anna M. Coclite

Anna M. Coclite has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of coating surfaces using initiated plasma-enhanced chemical vapor deposition
    Patent number: 9884341
    Abstract: Disclosed is an organic coating with a high degree of global planarization. Further disclosed is an iPECVD-based method of coating a substrate with an organic layer having a high degree of global planarization. Disclosed is a flexible, alternating organic and inorganic multi-layer coating with low water permeability, a high-degree of transparency, and a high-degree of global planarization. Also disclosed is an iPECVD-based method of coating a substrate with the alternating organic and inorganic multi-layer coating.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: February 6, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Karen K. Gleason, Anna M. Coclite
  • Articles and methods for stem cell differentiation
    Patent number: 9816070
    Abstract: Articles and methods for stem cell differentiation are generally described. In some embodiments, an article for stem cell differentiation may comprise an oxygen permeable substrate having at least a portion of a surface coated with a matrix. The matrix may allow the surface chemistry of the substrate to be altered, such that the cell-substrate surface interactions may be finely controlled without substantially affecting the oxygen permeability of the substrate. The surface chemistry may be altered to promote directed stem cell differentiation by, e.g., modification of the matrix surface with a specific density of biological molecules. In some embodiments, methods for stem cell differentiation may comprise directing the differentiation of stem cells on the articles, described herein, under suitable environmental conditions.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: November 14, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Clark K. Colton, Karen K. Gleason, Anna M. Coclite, Amanda R. Dilenno
  • ARTICLES AND METHODS FOR STEM CELL DIFFERENTIATION
    Publication number: 20140370598
    Abstract: Articles and methods for stem cell differentiation are generally described. In some embodiments, an article for stem cell differentiation may comprise an oxygen permeable substrate having at least a portion of a surface coated with a matrix. The matrix may allow the surface chemistry of the substrate to be altered, such that the cell-substrate surface interactions may be finely controlled without substantially affecting the oxygen permeability of the substrate. The surface chemistry may be altered to promote directed stem cell differentiation by, e.g., modification of the matrix surface with a specific density of biological molecules. In some embodiments, methods for stem cell differentiation may comprise directing the differentiation of stem cells on the articles, described herein, under suitable environmental conditions.
    Type: Application
    Filed: June 13, 2014
    Publication date: December 18, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Clark K. Colton, Karen K. Gleason, Anna M. Coclite, Amanda R. Diienno
  • Methods of Coating Surfaces Using Initiated Plasma-Enhanced Chemical Vapor Deposition
    Publication number: 20130040102
    Abstract: Disclosed is an organic coating with a high degree of global planarization. Further disclosed is an iPECVD-based method of coating a substrate with an organic layer having a high degree of global planarization. Disclosed is a flexible, alternating organic and inorganic multi-layer coating with low water permeability, a high-degree of transparency, and a high-degree of global planarization. Also disclosed is an iPECVD-based method of coating a substrate with the alternating organic and inorganic multi-layer coating.
    Type: Application
    Filed: August 10, 2012
    Publication date: February 14, 2013
    Applicant: Massachusetts Institute of Technology
    Inventors: Karen K. Gleason, Anna M. Coclite