Abstract: A flush valve is provided for opening and closing a drain connecting a toilet bowl to a waste holding tank maintained at a partial vacuum. The flush valve is located external to the drain and comprises a pinch or nip mechanism surrounding a flexible section of the drain and an electro-mechanically operated actuator for moving the pinch mechanism to close the drain by pinching it shut or to open the drain by pulling it apart. The actuator includes a motor for moving a piston in opposite directions, and a cylinder having one end connected to the pinch mechanism and another end containing an enclosure. The piston is retained and reciprocable a limited distance within the enclosure, and a spring is interposed within the enclosure to provide biasing means between the piston and the cylinder.