Patents by Inventor Anna-Maria Hays Putnam

Anna-Maria Hays Putnam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC USES OF MODIFIED FGF-21 POLYPEPTIDES COMPRISING NON-NATURALLY OCCURRING AMINO ACIDS
    Publication number: 20150273075
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Application
    Filed: April 7, 2015
    Publication date: October 1, 2015
    Inventors: Thomas P. CUJEC, Roberto Mariani, Anna-Maria A. Hays Putnam, Wiliam M. Keefe, Nick Knudsen, Lillian Skidmore, Jason Pinkstaff, Vadim Kraynov
  • Modified FGF-21 polypeptides comprising non-naturally occurring amino acids
    Patent number: 9079971
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 2, 2013
    Date of Patent: July 14, 2015
    Assignee: AMBRX, INC.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, William M. Keefe, Nick Knudsen, Lillian Ho, Jason Pinkstaff, Vadim Kraynov
  • Modified human plasma polypeptide or Fc scaffolds and their uses
    Patent number: 9074010
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: July 7, 2015
    Assignee: Ambrx, Inc.
    Inventors: Joseph Sheffer, Thea Norman, Richard D. Dimarchi, Anna-Maria A. Hays Putnam, Feng Tian, Stephanie Chu, Denise Krawitz, Ho Sung Cho
  • Prostate-Specific Membrane Antigen Antibody Drug Conjugates
    Publication number: 20150152190
    Abstract: This invention relates to prostate-specific membrane antigen (PSMA) antibodies and antibody drug conjugates comprising at least one non-naturally-encoded amino acid. Disclosed herein are ?PSMA antibodies with one or more non-naturally encoded amino acids and further disclosed are antibody drug conjugates wherein the ?PSMA antibodies of the invention are conjugated to one or more toxins. Also disclosed herein are non-natural amino acid dolastatin analogs that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such dolastatin analogs. Typically, the modified dolastatin analogs include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Further disclosed are methods for using such non-natural amino acid antibody drug conjugates, dolastatin analogs, and modified non-natural amino acid dolastatin analogs, including therapeutic, diagnostic, and other biotechnology uses.
    Type: Application
    Filed: June 7, 2013
    Publication date: June 4, 2015
    Applicant: Ambrx, Inc.
    Inventors: Richard S. Barnett, Feng Tian, Anna-Maria A. Hays Putnam, Marco Gymnopoulos, Nick Knudsen, Andrew Beck, Ying Sun
  • MODIFIED BOVINE SOMATOTROPIN POLYPEPTIDES AND THEIR USES
    Publication number: 20150152159
    Abstract: Modified bovine somatotropin polypeptides and uses thereof are provided.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 4, 2015
    Inventor: Anna-Maria A. HAYS PUTNAM
  • Anti-PSMA Antibodies Conjugated to Nuclear Receptor Ligand Polypeptides
    Publication number: 20150152187
    Abstract: This invention relates to anti-prostate-specific membrane antigen antibodies (?PSMA) and ?PSMA antibody—nuclear receptor ligand (NRL) conjugates comprising at least one non-naturally-encoded amino acid.
    Type: Application
    Filed: June 14, 2013
    Publication date: June 4, 2015
    Applicant: Ambrx, Inc.
    Inventors: Ying Sun, Ning Zou, Amha Hewet, Jason K. Pinkstaff, Shailaja Srinagesh, Richard S. Barnett, Feng Tian, Anna-Maria A. Hays Putnam, Marco Gymnopoulos, Nick Knudsen, Andrew Beck
  • Modified insulin polypeptides and their uses
    Patent number: 8946148
    Abstract: Modified insulin polypeptides and their uses thereof are provided.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: February 3, 2015
    Assignee: Ambrx, Inc.
    Inventors: Zhenwei Miao, Denise Krawitz, Vadim Kraynov, Feng Tian, Bee-Cheng Sim, Lillian Skidmore, Anna-Maria A. Hays Putnam, Nick Knudsen, Michael Deguzman
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20140296487
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: November 22, 2013
    Publication date: October 2, 2014
    Applicant: AMBRX, INC.
    Inventors: Joseph SHEFFER, Thea NORMAN, Richard D. DIMARCHI, Anna-Maria A. HAYS PUTNAM, Feng TIAN, Stephanie CHU, Denise KRAWITZ, Ho Sung CHO
  • Modified Human Growth Hormone Polypeptides and Their Uses
    Publication number: 20140296145
    Abstract: Modified human growth hormone polypeptides and uses thereof are provided.
    Type: Application
    Filed: April 2, 2014
    Publication date: October 2, 2014
    Applicant: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Richard DiMarchi, Anna-Maria Hays Putnam, Troy Wilson, Bee-Cheng Sim, David Litzinger
  • MODIFIED ANIMAL ERYTHROPOIETIN POLYPEPTIDES AND THEIR USES
    Publication number: 20140011740
    Abstract: Modified animal erythropoietin polypeptides and uses thereof are provided.
    Type: Application
    Filed: September 20, 2013
    Publication date: January 9, 2014
    Applicants: Eli Lilly Company, Ambrx, Inc.
    Inventors: Feng TIAN, Anna-Maria A. HAYS PUTNAM, Frank SONG, Stephanie CHU, Joseph SHEFFER, Richard S. BARNETT, Marc SILADI, Kyle ATKINSON, Darin LEE, Peter C. CANNING
  • Modified human plasma polypeptide or Fc scaffolds and their uses
    Patent number: 8618257
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: December 31, 2013
    Assignee: Ambrx, Inc.
    Inventors: Joseph Sheffer, Thea Norman, Richard D. Dimarchi, Anna-Maria A. Hays Putnam, Feng Tian, Stephanie Chu, Denise Krawitz, Ho Sung Cho
  • Modified animal erythropoietin polypeptides and their uses
    Patent number: 8569233
    Abstract: Modified animal erythropoietin polypeptides and uses thereof are provide.
    Type: Grant
    Filed: July 24, 2012
    Date of Patent: October 29, 2013
    Assignees: Eli Lilly and Company, AMBRX, Inc.
    Inventors: Feng Tian, Anna-Maria A. Hays Putnam, Frank Song, Stephanie Chu, Joseph Sheffer, Richard S. Barnett, Marc Siladi, Kyle Atkinson, Darin Lee, Peter C. Canning
  • Methods of making FGF-21 mutants comprising non-naturally encoded phenylalanine derivatives
    Patent number: 8383365
    Abstract: Modified FGF-21 polypeptides and uses thereof are provided.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: February 26, 2013
    Assignee: AMBRX, Inc.
    Inventors: Thomas P. Cujec, Roberto Mariani, Anna-Maria A. Hays Putnam, William M. Keefe, Nick Knudsen, Lillian Skidmore (Nee Ho), Jason Pinkstaff, Vadim Kraynov
  • MODIFIED ANIMAL ERYTHROPOIETIN POLYPEPTIDES AND THEIR USES
    Publication number: 20130017995
    Abstract: Modified animal erythropoietin polypeptides and uses thereof are provide.
    Type: Application
    Filed: July 24, 2012
    Publication date: January 17, 2013
    Applicants: ELI LILLY AND COMPANY, AMBRX, INC.
    Inventors: Feng TIAN, Anna-Maria A. HAYS PUTNAM, Frank SONG, Stephanie CHU, Joseph SHEFFER, Richard S. BARNETT, Marc E. SILADI, Kyle ATKINSON, Darin LEE, Peter C. CANNING
  • Modified interferon beta polypeptides and their uses
    Patent number: 8329869
    Abstract: Modified interferon beta polypeptides and uses thereof are provided.
    Type: Grant
    Filed: January 6, 2012
    Date of Patent: December 11, 2012
    Assignee: Ambrx, Inc.
    Inventors: Vadim Kraynov, Nick Knudsen, Anna-Maria A. Hays Putnam, Denise Krawitz, Jason Pinkstaff, Heather Myler
  • Modified animal erythropoietin polypeptides and their uses
    Patent number: 8278418
    Abstract: Modified animal erythropoietin polypeptides and uses thereof are provide.
    Type: Grant
    Filed: September 25, 2009
    Date of Patent: October 2, 2012
    Assignee: Ambrx, Inc.
    Inventors: Feng Tian, Anna-Maria A. Hays Putnam, Frank Song, Stephanie Chu, Joseph Sheffer, Richard S. Barnett, Marc E. Siladi, Kyle Atkinson, Darin Lee, Peter C. Canning
  • MODIFIED INTERFERON BETA POLYPEPTIDES AND THEIR USES
    Publication number: 20120197006
    Abstract: Modified interferon beta polypeptides and uses thereof are provided.
    Type: Application
    Filed: January 6, 2012
    Publication date: August 2, 2012
    Applicant: AMBRX, INC.
    Inventors: Vadim KRAYNOV, Nick KNUDSEN, Anna-Maria A. HAYS PUTNAM, Denise KRAWITZ, Jason PINKSTAFF, Heather MYLER
  • Modified human interferon polypeptides and their uses
    Patent number: 8232371
    Abstract: Modified interferon polypeptides with at least one non-naturally-encoded amino acid and uses thereof are provided.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: July 31, 2012
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria A. Hays Putnam, Troy E. Wilson
  • Modified Human Plasma Polypeptide or Fc Scaffolds and Their Uses
    Publication number: 20120190827
    Abstract: Modified human plasma polypeptides or Fc and uses thereof are provided.
    Type: Application
    Filed: August 11, 2011
    Publication date: July 26, 2012
    Applicant: AMBRX, INC.
    Inventors: Joseph SHEFFER, Thea NORMAN, Richard D. DIMARCHI, Anna-Maria A. HAYS PUTNAM, Feng TIAN, Stephanie CHU, Denise KRAWITZ, Ho Sung CHO
  • Modified Leptin Polypeptides and Their Uses
    Publication number: 20120149636
    Abstract: Modified human leptin polypeptides and uses thereof are provided.
    Type: Application
    Filed: February 5, 2009
    Publication date: June 14, 2012
    Applicant: AMBRX, INC.
    Inventors: Vadim Kraynov, Anna-Maria A. Hays Putnam, Nick Knudsen, Jason Pinkstaff, Heather Myler, Lorraine Sullivan