Patents by Inventor Anna Romert

Anna Romert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-CIS retinol dehydrogenase activity, and which associates with p63, a portion of a retinol binding protein receptor
    Publication number: 20030032169
    Abstract: In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has been discovered. This protein, referred to an “p32,” forms an oligomeric protein complex with the previously characterized p63 protein, a component of the membrane receptor for RBP. A nucleic acid molecule which codes for the p32 protein has also been isolated and sequence analysis shows that the p32 protein belongs to the family of short chain alcohol dehydrogenases, and exhibits 11-cis retinol dehydrogenase activity, the enzyme which catalyzes conversion of 11-cis-retinol into 11-cis retinaldehyde.
    Type: Application
    Filed: May 4, 2001
    Publication date: February 13, 2003
    Applicant: Ludwig Institute for Cancer Research
    Inventors: Ulf Eriksson, Andras Simon, Anna Romert
  • Isolated proteins having retinol dehydrogenase activity, and which associate with retinol binding receptors
    Patent number: 6399344
    Abstract: Isolated membrane associated proteins which have a molecular weight of from about 30 kD to about 36 kilodaltons as determined by SDS-PAGE, are disclosed. The proteins have cis retinol dehydrogenase activity, such as 9, 11 or 13 cis retinol dehydrogenase activity, or cis activity at more than one position. Other trans-retinol dehydrogenases are also disclosed. Nucleic acid molecules which code for the proteins are also disclosed.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: June 4, 2002
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Ulf Eriksson, Andras Simon, Anna Romert
  • Isolated nucleic acid molecule which codes for a 32 KDA protein having 11-CIS retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
    Patent number: 6280997
    Abstract: In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has been discovered. This protein, referred to an “p32,” forms an oligomeric protein complex with the previously characterized p63 protein, a component of the membrane receptor for RBP. A nucleic acid molecule which codes for the p32 protein has also been isolated and sequence analysis shows that the p32 protein belongs to the family of short chain alcohol dehydrogenases, and exhibits 11-cis retinol dehydrogenase activity, the enzyme which catalyzes conversion of 11-cis-retinol into 11-cis retinaldehyde.
    Type: Grant
    Filed: October 11, 1996
    Date of Patent: August 28, 2001
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Ulf Eriksson, Andras Simon, Anna Romert
  • Isolated nucleic acid molecule which codes for a 32 kDa protein having 11-cis retinol dehydrogenase activity, and which associates with P63, a portion of a retinol binding protein receptor
    Patent number: 5972646
    Abstract: In accordance with this invention, an RPE cell membrane associated protein which has a molecular weight of about 32 kd, as determined by SDS-PAGE, has been discovered. This protein, referred to an "p32," forms an oligomeric protein complex with the previously characterized p63 protein, a component of the membrane receptor for RBP. A nucleic acid molecule which codes for the p32 protein has also been isolated and sequence analysis shows that the p32 protein belongs to the family of short chain alcohol dehydrogenases, and exhibits 11-cis retinol dehydrogenase activity, the enzyme which catalyzes conversion of 11-cis-retinol into 11-cis retinaldehyde.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: October 26, 1999
    Assignee: Ludwig Institute for Cancer Research
    Inventors: Ulf Eriksson, Andras Simon, Anna Romert