Abstract: The present invention refers to compositions comprising a LH-RH-analogue and/or pharmaceutically acceptable salts thereof in a low-dose and a degradation-resistant polylactide suitable for the preparation of subcutaneous implants. Sterilization of the polylactide via gamma-radiation as well as temperature stress result in a negligible decomposition of less than 1000 Dalton.

Abstract: The present invention refers to compositions comprising a LH-RH-analogue and/or pharmaceutically acceptable salts thereof in a low-dose and a degradation-resistant polylactide suitable for the preparation of subcutaneous implants. Sterilisation of the polylactide via gamma-radiation as well as temperature stress result in a negligible decomposition of less than 1000 Dalton.

Abstract: The invention relates to a matrix-controlled transdermal therapeutic system comprising (i) an active-ingredient-impermeable cover layer, (ii) a self-adhesive matrix layer, or a plurality of matrix layers of which at least the matrix layer exposed while applying the system is self-adhesive, or one or more matrix layers whose surface remote from the cover layer and intended for adhesion at the application site is coated with an adhesive, the matrix layers comprising at least one ACE inhibitor (angiotensin converting enzyme inhibitor), the metabolite of which is a dicarboxylic acid and which is selected from the following group:

Abstract: The invention relates to a patch for transdermal application of pergolid and its pharmaceutically acceptable salts.

Abstract: The invention relates to a transdermal system containing at least one angiotensin-converting enzyme inhibitor.

Abstract: The object of the present invention is an oral drug preparation containing the .gamma.-cyclodextrin complex of diclofenac or pharmaceutically acceptable salts thereof, especially the sodium salt prepared by known methods, and by which the gastro-intestinal irritancy of diclofenac, at the same or improved bioavailability, can be considerably decreased.

Abstract: The invention relates to a plaster for transdermal application with an outer covering or backing layer, a self-adhesive matrix or a reservoir and a removable protective liner or release layer, the matrix or the reservoir containing tacrine and selegiline (optionally in the form of their pharmaceutically compatible salts) as active substance.

Abstract: A transdermal system in the form of a patch that comprises a tamoxifen derivative and an absorption-promoting additive for systemic administration.