Patents by Inventor Anna SHEVCHENKO

Anna SHEVCHENKO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT FORMS OF A 4H-PYRAN-4-ONE STRUCTURED CYP11 A1 INHIBITOR
    Publication number: 20250257054
    Abstract: The present invention relates to novel salts, particularly crystalline salts, of 5-((1-(methylsulfonyl)piperidin-4-yl)methoxy)-2-((5-(trifluoromethyl)isoindolin-2-yl)methyl)-4H-pyran-4-one (I) which are particularly suitable for use in the manufacture of pharmaceutical compositions. Furthermore, the invention relates to pharmaceutical compositions comprising such novel salts. Compound (I) is a selective inhibitor of CYP11A1 enzyme and is useful in the treatment of hormonally regulated cancers, such as prostate cancer and breast cancer.
    Type: Application
    Filed: October 27, 2022
    Publication date: August 14, 2025
    Inventors: David DIN BELLE, Oskari KARJALAINEN, Miika KARJOMAA, Mihaela POP, Petteri RUMMAKKO, Anna SHEVCHENKO, Kai SINERVO
  • NOVEL SALT FORMS OF A 4H-PYRAN-4-ONE STRUCTURED CYP11A1 INHIBITOR
    Publication number: 20240158377
    Abstract: The present invention relates to novel salts, particularly crystalline salts, of 2-(isoindolin-2-ylmethyl)-5-((1-(methyl sulfonyl)piperidin-4-yl)methoxy)-4H-pyran-4-one (I) which are particularly suitable for use in the manufacture of pharmaceutical 5 compositions. Furthermore, the invention relates to pharmaceutical compositions comprising such novel salts. Compound (I) is a selective inhibitor of CYP11A1 enzyme and is useful in the treatment of hormonally regulated cancers, such as prostate cancer and breast cancer.
    Type: Application
    Filed: February 28, 2022
    Publication date: May 16, 2024
    Applicant: Orion Corporation
    Inventors: Oskari Karjalainen, Mikko Mäkelä, Mihaela Pop, Petteri Rummakko, Anna Shevchenko, Kai Sinervo, Eija Tiainen
  • SOLID FORMS OF A 4H-PYRAN-4-ONE STRUCTURED CYP11A1 INHIBITOR
    Publication number: 20240158378
    Abstract: The present invention relates to novel solid forms, particularly crystalline forms, of 2-(isoindolin-2-ylmethyl)-5-((1-(methylsulfonyl)piperidin-4-yl)methoxy)-4H-pyran-4-one (I). Compound (I) is a selective inhibitor of CYP11A1 enzyme and is useful in the treatment of hormonally regulated cancers, such as prostate cancer and breast cancer.
    Type: Application
    Filed: February 28, 2022
    Publication date: May 16, 2024
    Applicant: Orion Corporation
    Inventors: Oskari Karjalainen, Mikko Mäkelä, Mihaela Pop, Anna Shevchenko, Eija Tiainen
  • PHARMACEUTICAL COMPOSITIONS OF A KINASE INHIBITOR
    Publication number: 20230119355
    Abstract: The present invention relates to pharmaceutical compositions comprising hydrochloride salt of N-(2?,4?-difluoro-5-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)-[1,1?-biphenyl]-3-yl)cyclopropanesulfonamide (I) as an active ingredient and copovidone as an excipient. Compound (I) is a selective inhibitor of FGFR/VEGFR kinase families and is useful in the treatment of cancer.
    Type: Application
    Filed: March 5, 2021
    Publication date: April 20, 2023
    Applicant: AURIGENE DISCOVERY TECHNOLOGIES LIMITED
    Inventors: Frederic DARGELAS, Piritta KOISTINEN, Laura LEIMU, Laura MATILAINEN, Henri METSALA, Anna SHEVCHENKO