Patents by Inventor Anna Shifrina

Anna Shifrina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20230404954
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: April 28, 2023
    Publication date: December 21, 2023
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20230121825
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: June 7, 2022
    Publication date: April 20, 2023
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20200375930
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: April 14, 2020
    Publication date: December 3, 2020
    Inventors: Thuy-Anh TRAN, Weichao CHEN, Bryan A. KRAMER, Abu J.M. SADEQUE, Anna SHIFRINA, Young-Jun SHIN, Pureza VALLAR, Ning ZOU
  • Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
    Patent number: 10668033
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: June 2, 2020
    Assignee: ARENA PHARMACEUTICALS, INC.
    Inventors: Thuy-Anh Tran, Weichao Chen, Bryan A. Kramer, Abu J. M. Sadeque, Anna Shifrina, Young-Jun Shin, Pureza Vallar, Ning Zou
  • Modified-release dosage forms of 5-HTagonists useful for weight management
    Patent number: 10463676
    Abstract: The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: November 5, 2019
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Zezhi Jesse Shao, Anthony C. Blackburn, Andrew J. Grottick, Michael E. Morgan, Jaimie Karyn Rueter, Anna Shifrina, Scott Stirn, Libo Yang, Woo Hyun Yoon
  • Modified-Release Dosage Forms of 5-Ht2c Agonists Useful for Weight Management
    Publication number: 20190275055
    Abstract: The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them.
    Type: Application
    Filed: January 7, 2019
    Publication date: September 12, 2019
    Inventors: Zezhi Jesse Shao, Anthony C. Blackburn, Andrew J. Grottick, Michael E. Morgan, Jaimie Karyn Rueter, Anna Shifrina, Scott Stirn, Libo Yang, Woo Hyun Yoon
  • Modified-release dosage forms of 5-HTagonists useful for weight management
    Patent number: 10226471
    Abstract: The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: March 12, 2019
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Zezhi Jesse Shao, Anthony C. Blackburn, Andrew J. Grottick, Michael E. Morgan, Jaimie Karyn Rueter, Anna Shifrina, Scott Stirn, Libo Yang, Woo Hyun Yoon
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20170360730
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: March 2, 2017
    Publication date: December 21, 2017
    Inventors: Thuy-Anh Tran, Weichao Chen, Bryan A. Kramer, Abu J.M. Sadeque, Anna Shifrina, Young-Jun Shin, Pureza Vallar, Ning Zou
  • MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT
    Publication number: 20170246179
    Abstract: The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them.
    Type: Application
    Filed: February 10, 2017
    Publication date: August 31, 2017
    Inventors: Zezhi Jesse Shao, Anthony C. Blackburn, Andrew J. Grottick, Michael E. Morgan, Jaimie Karyn Rueter, Anna Shifrina, Scott Stirn, Libo Yang, Woo Hyun Yoon
  • NON-HYGROSCOPIC SALTS OF 5-HT2C AGONISTS
    Publication number: 20170096398
    Abstract: Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management.
    Type: Application
    Filed: May 10, 2016
    Publication date: April 6, 2017
    Inventors: Anthony C. Blackburn, Yun Shan, Anna Shifrina, Scott Stirn
  • Non-hygroscopic salts of 5-HTagonists
    Patent number: 9365521
    Abstract: Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: June 14, 2016
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Anthony C. Blackburn, Yun Shan, Anna Shifrina, Scott Stirn
  • SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS
    Publication number: 20160151381
    Abstract: Salts of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with optically active acids, and pharmaceutical compositions comprising them that are useful for, inter alia, weight management.
    Type: Application
    Filed: July 29, 2015
    Publication date: June 2, 2016
    Inventors: Anthony C. Blackburn, William Lucas Betts, III, Jaimie Karyn Rueter, Yun Shan, Anna Shifrina, Scott Stirn
  • Salts of lorcaserin with optically active acids
    Patent number: 9248133
    Abstract: Salts of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with optically active acids, and pharmaceutical compositions comprising them that are useful for, inter alia, weight management.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: February 2, 2016
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Anthony C. Blackburn, William Lucas Betts, III, Jaimie Karyn Rueter, Yun Shan, Anna Shifrina, Scott Stirn
  • Processes for the preparation of 5-HTreceptor agonists
    Patent number: 9045431
    Abstract: Processes and intermediates for preparing salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and pharmaceutically acceptable solvates and hydrates thereof, that are useful for, inter alia, weight management.
    Type: Grant
    Filed: June 1, 2011
    Date of Patent: June 2, 2015
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Anthony C. Blackburn, Anna Shifrina
  • MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO
    Publication number: 20150126527
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Application
    Filed: October 9, 2014
    Publication date: May 7, 2015
    Inventors: Thuy-Anh Tran, Weichao Chen, Bryan A. Kramer, Abu J.M. Sadeque, Anna Shifrina, Young-Jun Shin, Pureza Vallar, Ning Zou
  • Modulators of the prostacyclin (PGI2) receptor useful for the treatment of disorders related thereto
    Patent number: 8895776
    Abstract: The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor.
    Type: Grant
    Filed: March 17, 2009
    Date of Patent: November 25, 2014
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Thuy-Anh Tran, Weichao Chen, Bryan A. Kramer, Abu J. M. Sadeque, Anna Shifrina, Young-Jun Shin, Pureza Vallar, Ning Zou
  • FAST-DISSOLVE DOSAGE FORMS OF 5-HT2C AGONISTS
    Publication number: 20140148442
    Abstract: Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management.
    Type: Application
    Filed: August 31, 2011
    Publication date: May 29, 2014
    Inventors: Anthony C. Blackburn, Scott Stirn, Yun Shan, Anna Shifrina
  • MODIFIED-RELEASE DOSAGE FORMS OF 5-HT2C AGONISTS USEFUL FOR WEIGHT MANAGEMENT
    Publication number: 20130315994
    Abstract: The present invention relates to methods for weight management that utilize modified-release dosage forms comprising (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts and crystalline forms thereof. The present invention further relates to (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine salts, crystalline forms thereof and modified-release dosage forms comprising them.
    Type: Application
    Filed: August 31, 2011
    Publication date: November 28, 2013
    Inventors: Zezhi Jesse Shao, Anthony C. Blackburn, Andrew J. Grottick, Michael Morgan, Jaimie Karyn Rueter, Anna Shifrina, Scott Stirn, Libo Yang, Woo Hyun Yoon
  • NON-HYGROSCOPIC SALTS OF 5-HT2C AGONISTS
    Publication number: 20130317005
    Abstract: Salts of the 5-HT2C-receptor agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, and dosage forms comprising them that are useful for, inter alia, weight management.
    Type: Application
    Filed: August 31, 2011
    Publication date: November 28, 2013
    Inventors: Anthony C. Blackburn, Yun Shan, Anna Shifrina, Scott Stirn
  • SALTS OF LORCASERIN WITH OPTICALLY ACTIVE ACIDS
    Publication number: 20130310369
    Abstract: Salts of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine with optically active acids, and pharmaceutical compositions comprising them that are useful for, inter alia, weight management.
    Type: Application
    Filed: August 31, 2011
    Publication date: November 21, 2013
    Inventors: Anthony C. Blackburn, William Lucas Betts, III, Jaimie Karyn Rueter, Yun Shan, Anna Shifrina, Scott Stim