Patents by Inventor Anna Voronova

Anna Voronova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to identify immunomodulators using cognate interaction of PKC-theta
    Patent number: 6054286
    Abstract: Compounds having immunomodulating activity are identified using a methodology which employs TER14687, TER10311 and/or TER17210 as standards. The effect candidate compounds have on PKC-theta interaction with cognate binding proteins is measured and compared with the standards. The interaction can be measured by a variety of techniques, including assessing translocation of said PKC-theta or fragment. Kits containing the TER14687, TER10311 and/or TER17210 standards are disclosed. TER14687, TER10311 and/or TER17210 are useful in modulating the immune system in a subject by reducing T-cell activity. TER14687, TER10311, TER17210 are used as leads to develop other compounds having immunomodulating activity.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: April 25, 2000
    Assignee: Telik, Inc.
    Inventors: Hugo O. Villar, John Patterson, Anna Voronova, Dorit Ron, Lawrence Kauvar, Gene Napolitano, Nicki Vasquez
  • Methods for identifying agents which block the interaction of fyn with PKC-theta, and uses thereof
    Patent number: 5776716
    Abstract: The present invention discloses that the fyn protein binds to the PKC-theta protein. Based on this observation, the present invention provides methods of identifying agents which can be used to modulate immune system activity by blocking fyn/PKC-theta binding and therapeutic methods using such agents.
    Type: Grant
    Filed: January 31, 1996
    Date of Patent: July 7, 1998
    Assignee: Terrapin Technologies, Inc.
    Inventors: Dorit Ron, Eugene W. Napolitano, Anna Voronova