Patents by Inventor Anna Z. Wec

Anna Z. Wec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibodies and cocktails for treatment of Ebola infections
    Patent number: 11407817
    Abstract: Described herein are compositions and methods for the prevention and treatment of ebolavirus infection. In certain embodiments of the present invention, monoclonal antibodies substantially similar to those described herein, as well as affinity matured variants thereof, alone or in combination, provide therapeutic efficacy in a patient against multiple species of ebolavirus.
    Type: Grant
    Filed: June 9, 2020
    Date of Patent: August 9, 2022
    Assignees: MAPP BIOPHARMACEUTICAL, INC., ALBERT EINSTEIN COLLEGE OF MEDICINE, ADIMAB, LLC
    Inventors: Zachary A. Bornholdt, Larry Zeitlin, Kartik Chandran, Anna Z. Wec, Laura Walker
  • Methods of treating filovirus infections utilizing bispecific antibodies and fusion proteins that bind EBOV and NPC1
    Patent number: 11149080
    Abstract: Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick C1 (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: October 19, 2021
    Assignee: Albert Einstein College of Medicine
    Inventors: Kartik Chandran, Anna Z. Wec, Elisabeth K. Nyakatura, Jonathan R. Lai
  • ANTIBODY THERAPEUTICS AGAINST FILOVIRUS INFECTIONS AND USES THEREOF
    Publication number: 20200199202
    Abstract: Disclosed are bispecific antibodies and bispecific fission constructs that bind to Niemann-Pick C1 (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.
    Type: Application
    Filed: June 19, 2019
    Publication date: June 25, 2020
    Applicant: ALBERT EINSTEIN COLLGE OF MEDICINE
    Inventors: Kartik Chandran, III, Anna Z. Wec, Elisabeth K. Nyakatura, Jonathan R. Lai
  • Bispecific antibodies and fusion proteins that bind to EBOV and NPC1
    Patent number: 10377815
    Abstract: Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick CI (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.
    Type: Grant
    Filed: May 4, 2016
    Date of Patent: August 13, 2019
    Assignee: Albert Einstein College of Medicine
    Inventors: Kartik Chandran, Anna Z. Wec, Elisabeth K. Nyakatura, Jonathan R. Lai
  • ANTIBODY THERAPEUTICS AGAINST FILOVIRUS INFECTIONS AND USES THEREOF
    Publication number: 20180141999
    Abstract: Disclosed are bispecific antibodies and bispecific fusion constructs that bind to Niemann-Pick CI (NPC1) receptor for treating or preventing filovirus infections, pharmaceutical compositions comprising the bispecific antibodies, and therapeutic methods using the bispecific antibodies.
    Type: Application
    Filed: May 4, 2016
    Publication date: May 24, 2018
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Kartik Chandran, Anna Z. Wec, Elisabeth K. Nyakatura, Jonathan R. Lai