Patents by Inventor Anna Zumsteg

Anna Zumsteg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20230079407
    Abstract: Provided herein are antibodies and antigen-binding fragments that bind MSR1 and methods of use thereof. According to certain embodiments, the antibodies bind human MSR1 with high affinity. In certain embodiments, the antibodies bind MSR1 without blocking, or blocking less than 90%, of modified LDL binding to MSR1. In some embodiments, the antibodies bind cell surface expressed-MSR1 and are internalized. The antibodies of the invention may be fully human antibodies. The invention includes anti-MSR1 antibodies, or antigen-binding fragments thereof, conjugated to drugs or therapeutic compounds.
    Type: Application
    Filed: April 22, 2022
    Publication date: March 16, 2023
    Inventors: Jesper GROMADA, Viktoria GUSAROVA, Amy HAN, Sokol HAXHINASTO, Christos KYRATSOUS, Andrew J. MURPHY, Thomas NITTOLI, William OLSON, Matthew SLEEMAN, Anna ZUMSTEG
  • Anti-MSR1 antibodies and methods of use thereof
    Patent number: 11377502
    Abstract: Provided herein are antibodies and antigen-binding fragments that bind MSR1 and methods of use thereof. According to certain embodiments, the antibodies bind human MSR1 with high affinity. In certain embodiments, the antibodies bind MSR1 without blocking, or blocking less than 90%, of modified LDL binding to MSR1. In some embodiments, the antibodies bind cell surface expressed-MSR1 and are internalized. The antibodies of the invention may be fully human antibodies. The invention includes anti-MSR1 antibodies, or antigen-binding fragments thereof, conjugated to drugs or therapeutic compounds.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: July 5, 2022
    Assignee: REGENERON PHARMACEUTICALS, INC.
    Inventors: Jesper Gromada, Viktoria Gusarova, Amy Han, Sokol Haxhinasto, Christos Kyratsous, Andrew J. Murphy, Thomas Nittoli, William Olson, Matthew Sleeman, Anna Zumsteg
  • ANTI-STAPHYLOCOCCUS ANTIBODIES AND USES THEREOF
    Publication number: 20200157193
    Abstract: Speciated antibodies or antigen-binding fragments that bind staphylococcal antigens are provided, where the antibodies and antigen-binding fragments have attenuated Fc binding to Protein A or homologous protein. Compositions comprising the antibodies and methods of use are also provided. The antibodies and compositions are useful for treating staphylococcal infection, reducing serum or kidney bacterial titers, and treating symptoms associated with staphylococcal infection. The antibodies may also prevent the severity and/or duration of the primary disease.
    Type: Application
    Filed: November 20, 2019
    Publication date: May 21, 2020
    Inventors: Anna Zumsteg, Christos Kyratsous, Brinda Prasad, Alida Coppi
  • ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF
    Publication number: 20190367631
    Abstract: Provided herein are antibodies and antigen-binding fragments that bind MSR1 and methods of use thereof. According to certain embodiments, the antibodies bind human MSR1 with high affinity. In certain embodiments, the antibodies bind MSR1 without blocking, or blocking less than 90%, of modified LDL binding to MSR1. In some embodiments, the antibodies bind cell surface expressed-MSR1 and are internalized. The antibodies of the invention may be fully human antibodies. The invention includes anti-MSR1 antibodies, or antigen-binding fragments thereof, conjugated to drugs or therapeutic compounds.
    Type: Application
    Filed: May 8, 2019
    Publication date: December 5, 2019
    Inventors: Jesper Gromada, Viktoria Gusarova, Amy Han, Sokol Haxhinasto, Christos Kyratsous, Andrew J. Murphy, Thomas Nittoli, William Olson, Matthew Sleeman, Anna Zumsteg