Patents by Inventor Annaliesa S. Anderson

Annaliesa S. Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides for inducing a protective immune response against
    Patent number: 8124108
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF1319e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: February 28, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook, III, William L. McClements, Donna L. Montgomery
  • Antigen-Binding Proteins Targeting S. Aureus Orf0657n
    Publication number: 20110091480
    Abstract: The present invention features antigen binding protein that bind an ORF0657n target region (SEQ ID NO: 1). ORF0657n is an S. aureus protein. ORF0657n target regions are provided by the mAb 1G3.BD4, mAb 2H2.BE11, mAb 13C7.BC1, and mAb 13G11.BF3 binding sites. In a lethal model challenge, mAb 2H2.BE11 and mAb 13C7.BC1 provided for increased survival against S. aureus infection. There was also protection demonstrated in an ex vivo model with either the IgG1 or the IgG2b form of mAb 2H2; and in a passive immunization murine indwelling catheter model using mAb 2H2.BE11.
    Type: Application
    Filed: January 23, 2007
    Publication date: April 21, 2011
    Inventors: Martha J. Brown, Annaliesa S. Anderson, Leslie D. Cope, Kathrin Ute Jansen, Tessie McNeely, Barrett R. Harvey, Eberhard Durr, Robin Ernst
  • POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS AUREUS
    Publication number: 20100247561
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1, uses of such polypeptides, and expression systems for producing such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full length S. aureus polypeptide. The full-length polypeptide is referred to herein as full-length “ORF0657n”. Polypeptides containing the amino acid sequence of SEQ ID NO: 1 were found to produce a protective immune response against S. aureus.
    Type: Application
    Filed: April 30, 2010
    Publication date: September 30, 2010
    Inventors: Annaliesa S. Anderson, Kathrin Ute Jansen, Rosemarie Kelly, Loren D. Schultz, Donna L. Montgomery, William L. McClements
  • ANTIGEN-BINDING PROTEINS TARGETING S. AUREUS ORF0657n
    Publication number: 20100166772
    Abstract: The present invention features antigen binding proteins that bind to a region found to have an epitope that can be targeted to provide protection against S. aureus infection. The region is designated herein as the “CS-D7” target region. The CS-D7 target region provides an S. aureus ORF0657n epitope that can be targeted to reduce the likelihood or severity of an S. aureus infection.
    Type: Application
    Filed: May 29, 2008
    Publication date: July 1, 2010
    Inventors: Annaliesa S. Anderson, Desmond J. Clark, Zhiqiang An, Fubao Wang, Susan L. Secore, Eberhard Durr, Leslie D. Cope, Tessie McNeely
  • POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS EPIDERMIDIS
    Publication number: 20100143390
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF1319e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Application
    Filed: January 18, 2008
    Publication date: June 10, 2010
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook, III, William L. McClements, Donna L. Montgomery
  • POLYPEPTIDES FOR INDUCING A PROTECTIVE IMMUNE RESPONSE AGAINST STAPHYLOCOCCUS EPIDERMIDIS
    Publication number: 20100104591
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF2695e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 29, 2010
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook III, William L. McClements, Donna L. Montgomery