Patents by Inventor Annalisa Bonfanti

Annalisa Bonfanti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
    Patent number: 9012435
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Grant
    Filed: July 19, 2013
    Date of Patent: April 21, 2015
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
    Publication number: 20130303499
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Application
    Filed: July 19, 2013
    Publication date: November 14, 2013
    Inventors: Francesca BENEDINI, Annalisa BONFANTI, Valerio CHIROLI, Rebecca STEELE, Ennio ONGINI, Stefano BIONDI
  • Glucocorticoids attached to nitrate esters via an aromatic linker in position 21 and their use in ophthalmology
    Patent number: 8518920
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: August 27, 2013
    Assignee: Nicox S.A.
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • GLUCOCORTICOIDS ATTACHED TO NITRATE ESTERS VIA AN AROMATIC LINKER IN POSITION 21 AND THEIR USE IN OPHTHALMOLOGY
    Publication number: 20110144073
    Abstract: The invention relates to nitrooxy derivatives of fluocinolone acetonide, triamcinolone acetonide, betamethasone and beclomethasone, methods for their preparation, pharmaceutical compositions containing these compounds, and methods of using these compounds and compositions for treating diabetic macular edema, diabetic retinopathy, macular degeneration, age-related macular degeneration and other diseases of retina and macula lutea.
    Type: Application
    Filed: July 7, 2009
    Publication date: June 16, 2011
    Inventors: Francesca Benedini, Annalisa Bonfanti, Valerio Chiroli, Rebecca Steele, Ennio Ongini, Stefano Biondi
  • CRYSTALLINE FORMS OF ATORVASTATIN 4-(NITROOXY) BUTYL ESTER
    Publication number: 20100152274
    Abstract: The present invention relates to two crystalline forms designated as form A and form B, of (?R,?R)-2(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbon-yl]-1H-pyrrole-1-heptanoic acid 4-(nitrooxy)butyl ester (atorvastatin 4-(nitrooxy)butyl ester), represented by the formula (I), The invention also relates to processes for the preparation of the forms A and B, to pharmaceutical compositions comprising the two forms, and to their use for treating and/or preventing acute coronary syndromes, stroke, neurodegenerative disorders, such as Alzheimer's and Parkinson's disease as well as autoimmune diseases, such as multiple sclerosis.
    Type: Application
    Filed: March 19, 2008
    Publication date: June 17, 2010
    Applicant: Nicox S.A.
    Inventors: Francesca Benedini, Stefano Biondi, Annalisa Bonfanti, Fabio Nicoli