Patents by Inventor Annapurna Karicherla

Annapurna Karicherla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8287458
    Abstract: Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: October 16, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Guy Vanney, Scott Salys, Thao Ngo, Elizabeth Nee, Annapurna Karicherla, Ravisankar Gurusamy, Gene A. Bornzin
  • Publication number: 20120197141
    Abstract: Systems, devices and methods of monitoring blood flow velocity are disclosed herein. For example, one method of monitoring blood flow velocity includes: locating a blood flow velocity sensor near the ostium in the coronary sinus; and sensing towards a portion of the aorta. A second example method includes: locating a blood flow velocity sensor in a vein; and sensing towards an adjacent artery. A third example method includes: locating a blood flow velocity sensor near the tricuspid valve; and sensing towards a tricuspid valve annulus. A fourth example method includes: locating a blood flow velocity sensor right ventricular outflow tract; and sensing towards a portion of the aorta. A fifth example method includes: locating a blood flow velocity sensor in the great cardiac vein; and sensing towards a left anterior descending artery. A sixth example method includes: locating a blood flow velocity sensor in the right atrial appendage; and sensing towards a portion of the aorta.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 2, 2012
    Applicant: PACESETTER, INC.
    Inventors: Guy Vanney, Thao Ngo, Scott Sjoquist, Dorab N. Sethna, Annapurna Karicherla, George K. Lewis, Dan E. Gutfinger, Gene A. Bornzin
  • Patent number: 8209031
    Abstract: An implantable lead includes a lead body, having a distal end and a proximal end, configured to be implanted in a patient, and a connector provided at the proximal end. A load detection assembly is provided on the lead body, wherein the load detection assembly includes a housing that holds a sensor and a load transfer element. The load transfer element engages the sensor and conveys a force induced on the load transfer element to the sensor. Optionally, the housing may isolate the sensor from lateral forces and the load transfer element may only convey, to the sensor, longitudinal forces that are directed in a predetermined single direction. For example, the load transfer element may only convey, to the sensor, longitudinal forces that are directed perpendicular to a surface of the sensor.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: June 26, 2012
    Assignee: Pacesetter, Inc.
    Inventors: Rodolfo Rodriguez, Annapurna Karicherla
  • Publication number: 20110137364
    Abstract: Tachyarrhythmia is treated by applying anti-tachycardia pacing through at least one multi-site electrode set located on, in or around the heart. The electrode set is arranged and located such that an electrical activation pattern having a wave-front between substantially flat and concave is generated through a reentrant circuit associated with the tachyarrhythmia. The electrode set may be one of a plurality of predefined, multi-site electrode sets located on, in or around the atria.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 9, 2011
    Applicant: PACESETTER, INC.
    Inventors: Kyungmoo Ryu, Jong Gill, Xiaoyi Min, Annapurna Karicherla, Gene A. Bornzin
  • Patent number: 7917216
    Abstract: Tachyarrhythmia is treated by applying anti-tachycardia pacing through at least one multi-site electrode set located on, in or around the heart. The electrode set is arranged and located such that an electrical activation pattern having a wave-front between substantially flat and concave is generated through a reentrant circuit associated with the tachyarrhythmia. The electrode set may be one of a plurality of predefined, multi-site electrode sets located on, in or around the atria. Alternatively, the electrode set may be formed using at least two selectable electrodes located on, in or around the atria.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: March 29, 2011
    Assignee: Pacesetter, Inc.
    Inventors: Kyungmoo Ryu, Jong Gill, Xiaoyi Min, Annapurna Karicherla, Gene A. Bornzin
  • Patent number: 7917214
    Abstract: Methods and systems of identifying an electrode or combination of electrodes of a multi-electrode device for pacing include selecting a first electrode or electrode combination as a first candidate; delivering a pacing pulse through the first candidate and determining a measurement based on sensed cardiac electrical activity resulting from the first candidate pacing; selecting a second candidate; delivering a pacing pulse through the second candidate and determining a measurement based on sensed cardiac electrical activity resulting from the second candidate pacing; comparing the measurement for the first and second candidates; and identifying the first or second candidate for pacing based on the comparison. The measurement may be one or more of activation time ?Tact, activation recovery interval (ARI), a fractioned electrogram width, and a standard deviation of a fractioned electrogram feature.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: March 29, 2011
    Assignee: Pacesetter, Inc.
    Inventors: Jong Gill, Annapurna Karicherla, Kyungmoo Ryu, Gene A. Bornzin
  • Patent number: 7908017
    Abstract: A method of delivering a myocardial infarction patch to a surface of a heart is disclosed herein. In one embodiment, the method includes deploying the patch from an intra pericardial lead.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: March 15, 2011
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Kevin L. Morgan
  • Patent number: 7632235
    Abstract: The implantable device is capable of performing thermal dilution analysis of the cardiac output of a patient using power delivered from an external source. By using power from an external source, the implantable device conserves its power resources for other purposes, such as for pacing or defibrillation therapy. In one example, an external programmer or bedside monitor provides power through a hand-held power delivery wand via electromagnetic induction, with the power routed from a subcutaneous coil to a heating element implanted in the right atrium, which heats blood as it passes through the right atrium. In another example, the heating element is formed of a material that generates heat in response to a beam of ultrasound provided by the wand. In either case, a downstream blood temperature profile is detected using a thermistor implanted in the pulmonary artery and cardiac output is then estimated by analyzing the temperature profile.
    Type: Grant
    Filed: April 5, 2005
    Date of Patent: December 15, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Xiaoyi Min, Peter Boileau, Jong Gill, Gene A. Bornzin
  • Patent number: 7627366
    Abstract: An exemplary method includes providing a first value indicative of electrode polarization, delivering a cardiac stimulus and determining a second value indicative of electrode polarization associated with the cardiac stimulus, comparing the second value to the first value to determine whether a change in cardiac condition has occurred and, based at least in part on the comparing, deciding whether to adjust a cardiac stimulation therapy.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: December 1, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Xiaoyi Min, Xiaozheng Zhang, Jong Gill
  • Publication number: 20090270741
    Abstract: Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.
    Type: Application
    Filed: April 25, 2008
    Publication date: October 29, 2009
    Inventors: Guy Vanney, Scott Salys, Elizabeth Nee, Thao Thu Nguyen, Annapurna Karicherla, Ravisankar Gurusamy
  • Patent number: 7610089
    Abstract: Embodiments include strain sensor devices for detecting movement, morphological changes or other physical parameters within a patient's body tissue. Some embodiments are directed specifically to measuring parameters within a patient's heart and may also be configured to communicate with an implantable stimulation device and associated external programming device.
    Type: Grant
    Filed: February 21, 2007
    Date of Patent: October 27, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Rodolfo Rodriguez, Annapurna Karicherla
  • Publication number: 20090249617
    Abstract: A method of fabricating an implantable medical device having a receptacle adapted to receive a connector assembly attached to a proximal end of an implantable lead. A distal end portion of the implantable lead carries at least one electrode electrically connected with a terminal contact on the connector assembly. The receptacle contains at least one internal insulative sealing surface. An anti-static coating comprising carbon nanotubes is applied to the at least one internal insulative sealing surface.
    Type: Application
    Filed: May 15, 2009
    Publication date: October 8, 2009
    Applicant: PACESETTER, INC.
    Inventors: Annapurna Karicherla, Buehl E. Truex, Sheldon Williams
  • Patent number: 7551967
    Abstract: An implantable medical lead for transmitting electrical signals between an implantable medical device and selected body tissue comprises a lead body having a distal end portion, a proximal end and an electrically insulating, elongated housing connecting the distal end portion and the proximal end. The proximal end of the lead body carries an electrical connector assembly adapted to be electrically connected to the implantable medical device and the distal end portion of the lead body carries at least one electrode electrically coupled to a terminal contact on the connector assembly. The lead comprises at least one surface susceptible during use of the lead to the accumulation of electrostatic charges, the at least one surface having a coating comprising carbon nanotubes.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: June 23, 2009
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Buehl E. Truex, Sheldon Williams
  • Patent number: 7450999
    Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: November 11, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
  • Patent number: 7448999
    Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: November 11, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
  • Patent number: 7418868
    Abstract: A body fluid pressure sensor module according to the invention comprises a housing having a first end and a second end and enclosing a pressure sensor. The pressure sensor is electrically coupled to a plurality of electrical conductors extending into the housing through a feedthrough disposed within, and hermetically sealing, the first end of the housing. The housing defines a chamber disposed between the feedthrough and the second end of the housing. The chamber contains a material in communication with the pressure sensor, the material being capable of transmitting pressure variations to the pressure sensor. The plurality of electrical conductors have ends within the housing, and the pressure sensor is mounted on the end of at least one of the conductors. Also disclosed are medical leads incorporating the pressure sensor module, and methods for fabricating the modules.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: September 2, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Sheldon Williams, Gene A. Bornzin, John W. Poore, Dion F. Davis
  • Patent number: 7389134
    Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: June 17, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
  • Patent number: 7347826
    Abstract: According to this technique of packaging a sensor device implantable in a living body so as to provide protection of the sensor device and to the living body itself, an electrical conductor of the sensor device is sealed in an insulating substrate extending between proximal and distal ends. The distal end of the electrical conductor is externally connected to an external sensor on the sensor device and the proximal end of the electrical conductor is externally connected to a distal end of a lead wire extending proximally to a pulse generator and these connections are embedded in an insulative sheath. The external sensor, substrate, and insulative sheath are encapsulated in a thin film of hermetic material without interference with the lead wire. In another embodiment, a layer of insulating material may underlie the hermetic material to encapsulate the external sensor and the substrate.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: March 25, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, John W. Poore
  • Patent number: 7338436
    Abstract: An elastic framework configured to be positioned around a portion of the heart has a plurality of first regions and a plurality of second regions positioned relative to the first regions. The framework allows for the positioning of the first regions and second regions adjacent the outer surface of the heart and is structured so that the regions experience different movement effects in response to expansion and contraction of the heart. A sensor network having at least one motion sensor system associated with one of the first regions and second regions is associated with the framework. The motion sensor system outputs data responsive to the relative movement effects of the first and second regions. A communications system in communication with the sensor network provides for the transmission of motion data to a location remote from the framework.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: March 4, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Jeffery D. Snell, Annapurna Karicherla
  • Patent number: 7340288
    Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: March 4, 2008
    Assignee: Pacesetter, Inc.
    Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams