Patents by Inventor Annapurna Karicherla
Annapurna Karicherla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8287458Abstract: Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.Type: GrantFiled: April 25, 2008Date of Patent: October 16, 2012Assignee: Pacesetter, Inc.Inventors: Guy Vanney, Scott Salys, Thao Ngo, Elizabeth Nee, Annapurna Karicherla, Ravisankar Gurusamy, Gene A. Bornzin
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Publication number: 20120197141Abstract: Systems, devices and methods of monitoring blood flow velocity are disclosed herein. For example, one method of monitoring blood flow velocity includes: locating a blood flow velocity sensor near the ostium in the coronary sinus; and sensing towards a portion of the aorta. A second example method includes: locating a blood flow velocity sensor in a vein; and sensing towards an adjacent artery. A third example method includes: locating a blood flow velocity sensor near the tricuspid valve; and sensing towards a tricuspid valve annulus. A fourth example method includes: locating a blood flow velocity sensor right ventricular outflow tract; and sensing towards a portion of the aorta. A fifth example method includes: locating a blood flow velocity sensor in the great cardiac vein; and sensing towards a left anterior descending artery. A sixth example method includes: locating a blood flow velocity sensor in the right atrial appendage; and sensing towards a portion of the aorta.Type: ApplicationFiled: January 28, 2011Publication date: August 2, 2012Applicant: PACESETTER, INC.Inventors: Guy Vanney, Thao Ngo, Scott Sjoquist, Dorab N. Sethna, Annapurna Karicherla, George K. Lewis, Dan E. Gutfinger, Gene A. Bornzin
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Patent number: 8209031Abstract: An implantable lead includes a lead body, having a distal end and a proximal end, configured to be implanted in a patient, and a connector provided at the proximal end. A load detection assembly is provided on the lead body, wherein the load detection assembly includes a housing that holds a sensor and a load transfer element. The load transfer element engages the sensor and conveys a force induced on the load transfer element to the sensor. Optionally, the housing may isolate the sensor from lateral forces and the load transfer element may only convey, to the sensor, longitudinal forces that are directed in a predetermined single direction. For example, the load transfer element may only convey, to the sensor, longitudinal forces that are directed perpendicular to a surface of the sensor.Type: GrantFiled: April 5, 2007Date of Patent: June 26, 2012Assignee: Pacesetter, Inc.Inventors: Rodolfo Rodriguez, Annapurna Karicherla
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Publication number: 20110137364Abstract: Tachyarrhythmia is treated by applying anti-tachycardia pacing through at least one multi-site electrode set located on, in or around the heart. The electrode set is arranged and located such that an electrical activation pattern having a wave-front between substantially flat and concave is generated through a reentrant circuit associated with the tachyarrhythmia. The electrode set may be one of a plurality of predefined, multi-site electrode sets located on, in or around the atria.Type: ApplicationFiled: February 16, 2011Publication date: June 9, 2011Applicant: PACESETTER, INC.Inventors: Kyungmoo Ryu, Jong Gill, Xiaoyi Min, Annapurna Karicherla, Gene A. Bornzin
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Patent number: 7917216Abstract: Tachyarrhythmia is treated by applying anti-tachycardia pacing through at least one multi-site electrode set located on, in or around the heart. The electrode set is arranged and located such that an electrical activation pattern having a wave-front between substantially flat and concave is generated through a reentrant circuit associated with the tachyarrhythmia. The electrode set may be one of a plurality of predefined, multi-site electrode sets located on, in or around the atria. Alternatively, the electrode set may be formed using at least two selectable electrodes located on, in or around the atria.Type: GrantFiled: July 19, 2006Date of Patent: March 29, 2011Assignee: Pacesetter, Inc.Inventors: Kyungmoo Ryu, Jong Gill, Xiaoyi Min, Annapurna Karicherla, Gene A. Bornzin
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Patent number: 7917214Abstract: Methods and systems of identifying an electrode or combination of electrodes of a multi-electrode device for pacing include selecting a first electrode or electrode combination as a first candidate; delivering a pacing pulse through the first candidate and determining a measurement based on sensed cardiac electrical activity resulting from the first candidate pacing; selecting a second candidate; delivering a pacing pulse through the second candidate and determining a measurement based on sensed cardiac electrical activity resulting from the second candidate pacing; comparing the measurement for the first and second candidates; and identifying the first or second candidate for pacing based on the comparison. The measurement may be one or more of activation time ?Tact, activation recovery interval (ARI), a fractioned electrogram width, and a standard deviation of a fractioned electrogram feature.Type: GrantFiled: September 6, 2007Date of Patent: March 29, 2011Assignee: Pacesetter, Inc.Inventors: Jong Gill, Annapurna Karicherla, Kyungmoo Ryu, Gene A. Bornzin
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Patent number: 7908017Abstract: A method of delivering a myocardial infarction patch to a surface of a heart is disclosed herein. In one embodiment, the method includes deploying the patch from an intra pericardial lead.Type: GrantFiled: August 28, 2006Date of Patent: March 15, 2011Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Kevin L. Morgan
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Patent number: 7632235Abstract: The implantable device is capable of performing thermal dilution analysis of the cardiac output of a patient using power delivered from an external source. By using power from an external source, the implantable device conserves its power resources for other purposes, such as for pacing or defibrillation therapy. In one example, an external programmer or bedside monitor provides power through a hand-held power delivery wand via electromagnetic induction, with the power routed from a subcutaneous coil to a heating element implanted in the right atrium, which heats blood as it passes through the right atrium. In another example, the heating element is formed of a material that generates heat in response to a beam of ultrasound provided by the wand. In either case, a downstream blood temperature profile is detected using a thermistor implanted in the pulmonary artery and cardiac output is then estimated by analyzing the temperature profile.Type: GrantFiled: April 5, 2005Date of Patent: December 15, 2009Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Xiaoyi Min, Peter Boileau, Jong Gill, Gene A. Bornzin
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Patent number: 7627366Abstract: An exemplary method includes providing a first value indicative of electrode polarization, delivering a cardiac stimulus and determining a second value indicative of electrode polarization associated with the cardiac stimulus, comparing the second value to the first value to determine whether a change in cardiac condition has occurred and, based at least in part on the comparing, deciding whether to adjust a cardiac stimulation therapy.Type: GrantFiled: May 6, 2005Date of Patent: December 1, 2009Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Xiaoyi Min, Xiaozheng Zhang, Jong Gill
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Publication number: 20090270741Abstract: Disclose herein is a method of measuring pressures in a coronary sinus. In one embodiment, the method includes: introducing a distal portion of a lead or tool into the coronary sinus, wherein the distal portion includes first and second pressure sensors and at least one selectably expandable member; expanding the at least one expandable member such that the first and second sensors are isolated from each other within the coronary sinus; and taking pressure measurements with the first and second sensors when isolated from each other.Type: ApplicationFiled: April 25, 2008Publication date: October 29, 2009Inventors: Guy Vanney, Scott Salys, Elizabeth Nee, Thao Thu Nguyen, Annapurna Karicherla, Ravisankar Gurusamy
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Patent number: 7610089Abstract: Embodiments include strain sensor devices for detecting movement, morphological changes or other physical parameters within a patient's body tissue. Some embodiments are directed specifically to measuring parameters within a patient's heart and may also be configured to communicate with an implantable stimulation device and associated external programming device.Type: GrantFiled: February 21, 2007Date of Patent: October 27, 2009Assignee: Pacesetter, Inc.Inventors: Rodolfo Rodriguez, Annapurna Karicherla
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Publication number: 20090249617Abstract: A method of fabricating an implantable medical device having a receptacle adapted to receive a connector assembly attached to a proximal end of an implantable lead. A distal end portion of the implantable lead carries at least one electrode electrically connected with a terminal contact on the connector assembly. The receptacle contains at least one internal insulative sealing surface. An anti-static coating comprising carbon nanotubes is applied to the at least one internal insulative sealing surface.Type: ApplicationFiled: May 15, 2009Publication date: October 8, 2009Applicant: PACESETTER, INC.Inventors: Annapurna Karicherla, Buehl E. Truex, Sheldon Williams
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Patent number: 7551967Abstract: An implantable medical lead for transmitting electrical signals between an implantable medical device and selected body tissue comprises a lead body having a distal end portion, a proximal end and an electrically insulating, elongated housing connecting the distal end portion and the proximal end. The proximal end of the lead body carries an electrical connector assembly adapted to be electrically connected to the implantable medical device and the distal end portion of the lead body carries at least one electrode electrically coupled to a terminal contact on the connector assembly. The lead comprises at least one surface susceptible during use of the lead to the accumulation of electrostatic charges, the at least one surface having a coating comprising carbon nanotubes.Type: GrantFiled: May 19, 2005Date of Patent: June 23, 2009Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Buehl E. Truex, Sheldon Williams
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Patent number: 7448999Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.Type: GrantFiled: February 7, 2005Date of Patent: November 11, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
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Patent number: 7450999Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.Type: GrantFiled: February 7, 2005Date of Patent: November 11, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
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Patent number: 7418868Abstract: A body fluid pressure sensor module according to the invention comprises a housing having a first end and a second end and enclosing a pressure sensor. The pressure sensor is electrically coupled to a plurality of electrical conductors extending into the housing through a feedthrough disposed within, and hermetically sealing, the first end of the housing. The housing defines a chamber disposed between the feedthrough and the second end of the housing. The chamber contains a material in communication with the pressure sensor, the material being capable of transmitting pressure variations to the pressure sensor. The plurality of electrical conductors have ends within the housing, and the pressure sensor is mounted on the end of at least one of the conductors. Also disclosed are medical leads incorporating the pressure sensor module, and methods for fabricating the modules.Type: GrantFiled: February 21, 2006Date of Patent: September 2, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Sheldon Williams, Gene A. Bornzin, John W. Poore, Dion F. Davis
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Patent number: 7389134Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.Type: GrantFiled: February 7, 2005Date of Patent: June 17, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams
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Patent number: 7347826Abstract: According to this technique of packaging a sensor device implantable in a living body so as to provide protection of the sensor device and to the living body itself, an electrical conductor of the sensor device is sealed in an insulating substrate extending between proximal and distal ends. The distal end of the electrical conductor is externally connected to an external sensor on the sensor device and the proximal end of the electrical conductor is externally connected to a distal end of a lead wire extending proximally to a pulse generator and these connections are embedded in an insulative sheath. The external sensor, substrate, and insulative sheath are encapsulated in a thin film of hermetic material without interference with the lead wire. In another embodiment, a layer of insulating material may underlie the hermetic material to encapsulate the external sensor and the substrate.Type: GrantFiled: October 16, 2003Date of Patent: March 25, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, John W. Poore
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Patent number: 7338436Abstract: An elastic framework configured to be positioned around a portion of the heart has a plurality of first regions and a plurality of second regions positioned relative to the first regions. The framework allows for the positioning of the first regions and second regions adjacent the outer surface of the heart and is structured so that the regions experience different movement effects in response to expansion and contraction of the heart. A sensor network having at least one motion sensor system associated with one of the first regions and second regions is associated with the framework. The motion sensor system outputs data responsive to the relative movement effects of the first and second regions. A communications system in communication with the sensor network provides for the transmission of motion data to a location remote from the framework.Type: GrantFiled: June 27, 2005Date of Patent: March 4, 2008Assignee: Pacesetter, Inc.Inventors: Jeffery D. Snell, Annapurna Karicherla
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Patent number: 7340288Abstract: An apparatus for and method of measuring pressure through a septum in a patient's heart is disclosed. A lead inserted into the right side of a heart is routed through the septum to gain access to the left side of the heart. The lead includes an attachment structure that secures the lead to one or both of the septal walls. The attachment structure may include at least one protruding tine, membrane, inflatable balloon, involuted spiral or J-lead that engage one or more sides of the septum. The lead also includes one or more sensors for measuring cardiac pressure on the left side of the heart and, as necessary, the right side of the heart.Type: GrantFiled: February 7, 2005Date of Patent: March 4, 2008Assignee: Pacesetter, Inc.Inventors: Annapurna Karicherla, Kevin L. Morgan, Gene A. Bornzin, Sheldon Williams