Patents by Inventor Annapurna Sachan

Annapurna Sachan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946078
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Grant
    Filed: April 22, 2021
    Date of Patent: April 2, 2024
    Assignee: Danisco US Inc.
    Inventors: Neeraj Pandey, Sina Pricelius, Annapurna Sachan, Stepan Shipovskov, Richard Bott, Ajit Kumar Satapathy
  • Publication number: 20210309983
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: April 22, 2021
    Publication date: October 7, 2021
    Inventors: NEERAJ PANDEY, SINA PRICELIUS, ANNAPURNA SACHAN, STEPAN SHIPOVSKOV, RICHARD BOTT, AJIT KUMAR SATAPATHY
  • Publication number: 20180362946
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, hav endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: December 16, 2016
    Publication date: December 20, 2018
    Inventors: Neeraj Pandey, Richard R. Bott, Sina Pricelius, Annapurna Sachan, Stepan Shipovskov, Ajit Satapathy
  • Patent number: 9273336
    Abstract: Methods are provided to obtain recombinant microbial cells having at least one genetic modification that increase the buoyant density of a recombinant microbial cell or the buoyant density of inclusion bodies produced within a recombinant microbial cell. Exemplified are genetic modifications that increase the buoyant density of a recombinant microbial cell expressing heterologous peptides and polypeptides. Increasing expression of the genes ysaB, glyQ, glyS or a combination thereof within the recombinant microbial cell produces cells or inclusion bodies having higher buoyant density. A similar effect was achieved by decreasing or disrupting expression of the endogenous gltA gene. Increases in buoyant density render peptide production more efficient with respect to time and costs.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: March 1, 2016
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Ritu Bhalla, Qi Chen, Qiong Cheng, Neeraj Pandey, Pierre E. Rouviere, Kristin Ruebling-Jass, Annapurna Sachan
  • Publication number: 20120214202
    Abstract: Methods are provided to obtain recombinant microbial cells having at least one genetic modification that increase the buoyant density of a recombinant microbial cell or the buoyant density of inclusion bodies produced within a recombinant microbial cell. Exemplified are genetic modifications that increase the buoyant density of a recombinant microbial cell expressing heterologous peptides and polypeptides. Increasing expression of the genes ysaB, glyQ, glyS or a combination thereof within the recombinant microbial cell produces cells or inclusion bodies having higher buoyant density. A similar effect was achieved by decreasing or disrupting expression of the endogenous gltA gene. Increases in buoyant density render peptide production more efficient with respect to time and costs.
    Type: Application
    Filed: June 21, 2011
    Publication date: August 23, 2012
    Applicant: E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Ritu Bhalla, Qi Chen, Qiong Cheng, Neeraj Pandey, Pierre E. Rouviere, Kristin Ruebling-Jass, Annapurna Sachan